1.
Curr Rev Pain
; 3(6): 458-472, 1999.
Artigo
em Inglês
| MEDLINE
| ID: mdl-10998705
RESUMO
An overview of the spinal administration of ketamine is presented. Ketamine acts as a noncompetitive antagonist of the NMDA receptor Ca(++ channel pore. This effect provides interesting possibilities in pain therapy. However, there are still contrasting results that seem to be due to a lack of comparative controlled studies. The presence of systemic and neurotoxic effects presently limits clinical use).