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1.
IEEE Trans Pattern Anal Mach Intell ; 45(6): 7308-7318, 2023 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-37015371

RESUMO

Graph Neural Networks (GNNs) have established themselves as state-of-the-art for many machine learning applications such as the analysis of social and medical networks. Several among these datasets contain privacy-sensitive data. Machine learning with differential privacy is a promising technique to allow deriving insight from sensitive data while offering formal guarantees of privacy protection. However, the differentially private training of GNNs has so far remained under-explored due to the challenges presented by the intrinsic structural connectivity of graphs. In this work, we introduce a framework for differential private graph-level classification. Our method is applicable to graph deep learning on multi-graph datasets and relies on differentially private stochastic gradient descent (DP-SGD). We show results on a variety of datasets and evaluate the impact of different GNN architectures and training hyperparameters on model performance for differentially private graph classification, as well as the scalability of the method on a large medical dataset. Our experiments show that DP-SGD can be applied to graph classification tasks with reasonable utility losses. Furthermore, we apply explainability techniques to assess whether similar representations are learned in the private and non-private settings. Our results can also function as robust baselines for future work in this area.

2.
Sci Rep ; 11(1): 13524, 2021 06 29.
Artigo em Inglês | MEDLINE | ID: mdl-34188157

RESUMO

The successful training of deep learning models for diagnostic deployment in medical imaging applications requires large volumes of data. Such data cannot be procured without consideration for patient privacy, mandated both by legal regulations and ethical requirements of the medical profession. Differential privacy (DP) enables the provision of information-theoretic privacy guarantees to patients and can be implemented in the setting of deep neural network training through the differentially private stochastic gradient descent (DP-SGD) algorithm. We here present deepee, a free-and-open-source framework for differentially private deep learning for use with the PyTorch deep learning framework. Our framework is based on parallelised execution of neural network operations to obtain and modify the per-sample gradients. The process is efficiently abstracted via a data structure maintaining shared memory references to neural network weights to maintain memory efficiency. We furthermore offer specialised data loading procedures and privacy budget accounting based on the Gaussian Differential Privacy framework, as well as automated modification of the user-supplied neural network architectures to ensure DP-conformity of its layers. We benchmark our framework's computational performance against other open-source DP frameworks and evaluate its application on the paediatric pneumonia dataset, an image classification task and on the Medical Segmentation Decathlon Liver dataset in the task of medical image segmentation. We find that neural network training with rigorous privacy guarantees is possible while maintaining acceptable classification performance and excellent segmentation performance. Our framework compares favourably to related work with respect to memory consumption and computational performance. Our work presents an open-source software framework for differentially private deep learning, which we demonstrate in medical imaging analysis tasks. It serves to further the utilisation of privacy-enhancing techniques in medicine and beyond in order to assist researchers and practitioners in addressing the numerous outstanding challenges towards their widespread implementation.

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