Detalhe da pesquisa
1.
Designed Ankyrin Repeat Proteins provide insights into the structure and function of CagI and are potent inhibitors of CagA translocation by the Helicobacter pylori type IV secretion system.
PLoS Pathog
; 19(5): e1011368, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37155700
2.
Determination of the substrate repertoire of ADAMTS2, 3, and 14 significantly broadens their functions and identifies extracellular matrix organization and TGF-ß signaling as primary targets.
FASEB J
; 30(5): 1741-56, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26740262
3.
Proteolytic control of TGF-ß co-receptor activity by BMP-1/tolloid-like proteases revealed by quantitative iTRAQ proteomics.
Cell Mol Life Sci
; 72(5): 1009-27, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25260970
4.
Procollagen C-proteinase enhancer grasps the stalk of the C-propeptide trimer to boost collagen precursor maturation.
Proc Natl Acad Sci U S A
; 110(16): 6394-9, 2013 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-23550162
5.
Metalloproteases meprin α and meprin ß are C- and N-procollagen proteinases important for collagen assembly and tensile strength.
Proc Natl Acad Sci U S A
; 110(35): 14219-24, 2013 Aug 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-23940311
6.
Mono- and bi-specific nanobodies targeting the CUB domains of PCPE-1 reduce the proteolytic processing of fibrillar procollagens.
J Mol Biol
; : 168667, 2024 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38901640
7.
Sizzled is unique among secreted frizzled-related proteins for its ability to specifically inhibit bone morphogenetic protein-1 (BMP-1)/tolloid-like proteinases.
J Biol Chem
; 287(40): 33581-93, 2012 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-22825851
8.
Identification of PCPE-2 as the endogenous specific inhibitor of human BMP-1/tolloid-like proteinases.
Nat Commun
; 14(1): 8020, 2023 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38049428
9.
Procollagen C-proteinase enhancer stimulates procollagen processing by binding to the C-propeptide region only.
J Biol Chem
; 286(45): 38932-8, 2011 Nov 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-21940633
10.
Dynamics of the secreted frizzled related protein Sizzled and potential implications for binding to bone morphogenetic protein-1 (BMP-1).
Sci Rep
; 12(1): 14850, 2022 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36050373
11.
Role of the netrin-like domain of procollagen C-proteinase enhancer-1 in the control of metalloproteinase activity.
J Biol Chem
; 285(21): 15950-9, 2010 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-20207734
12.
Procollagen C-proteinase enhancer-1 (PCPE-1), a potential biomarker and therapeutic target for fibrosis.
Matrix Biol Plus
; 11: 100062, 2021 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-34435180
13.
Strong cooperativity and loose geometry between CUB domains are the basis for procollagen c-proteinase enhancer activity.
J Biol Chem
; 284(48): 33437-46, 2009 Nov 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-19801683
14.
Inhibitors of BMP-1/tolloid-like proteinases: efficacy, selectivity and cellular toxicity.
FEBS Open Bio
; 8(12): 2011-2021, 2018 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-30524951
15.
Structural Basis for the Acceleration of Procollagen Processing by Procollagen C-Proteinase Enhancer-1.
Structure
; 26(10): 1384-1392.e3, 2018 10 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30078642
16.
Structural basis of homo- and heterotrimerization of collagen I.
Nat Commun
; 8: 14671, 2017 03 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28281531
17.
Interaction of Complement Defence Collagens C1q and Mannose-Binding Lectin with BMP-1/Tolloid-like Proteinases.
Sci Rep
; 7(1): 16958, 2017 12 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29209066
18.
BMP-1/tolloid-like proteinases synchronize matrix assembly with growth factor activation to promote morphogenesis and tissue remodeling.
Matrix Biol
; 44-46: 14-23, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25701650
19.
Processing of procollagen III by meprins: new players in extracellular matrix assembly?
J Invest Dermatol
; 130(12): 2727-35, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-20631730