Detalhe da pesquisa
1.
Ketone Supplementation Dampens Subjective and Objective Responses to Alcohol: Evidence From a Preclinical Rat Study and a Randomized, Cross-Over Trial in Healthy Volunteers.
Int J Neuropsychopharmacol
; 27(2)2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38315678
2.
PCSK9 inhibition attenuates alcohol-associated neuronal oxidative stress and cellular injury.
Brain Behav Immun
; 119: 494-506, 2024 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38657842
3.
Heroin- and Fentanyl-Induced Respiratory Depression in a Rat Plethysmography Model: Potency, Tolerance, and Sex Differences.
J Pharmacol Exp Ther
; 385(2): 117-134, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36828628
4.
Initial Pharmacological Characterization of a Major Hydroxy Metabolite of PF-5190457: Inverse Agonist Activity of PF-6870961 at the Ghrelin Receptor.
J Pharmacol Exp Ther
; 386(2): 117-128, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36631279
5.
Spironolactone as a potential new pharmacotherapy for alcohol use disorder: convergent evidence from rodent and human studies.
Mol Psychiatry
; 27(11): 4642-4652, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-36123420
6.
Corticosteroid sensitization drives opioid addiction.
Mol Psychiatry
; 27(5): 2492-2501, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35296810
7.
Alcohol dependence and withdrawal increase sensitivity of central amygdalar GABAergic synapses to the glucocorticoid receptor antagonist mifepristone in male rats.
Neurobiol Dis
; 164: 105610, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34995754
8.
Oxytocin blocks enhanced motivation for alcohol in alcohol dependence and blocks alcohol effects on GABAergic transmission in the central amygdala.
PLoS Biol
; 17(4): e2006421, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30990816
9.
A closer look at alcohol-induced changes in the ghrelin system: novel insights from preclinical and clinical data.
Addict Biol
; 27(1): e13033, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33908131
10.
Alcohol and Pain: A Translational Review of Preclinical and Clinical Findings to Inform Future Treatment Strategies.
Alcohol Clin Exp Res
; 44(2): 368-383, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31840821
11.
Mechanisms of Alcohol Addiction: Bridging Human and Animal Studies.
Alcohol Alcohol
; 55(6): 603-607, 2020 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32781467
12.
Detecting neuroinflammation in the brain following chronic alcohol exposure in rats: A comparison between in vivo and in vitro TSPO radioligand binding.
Eur J Neurosci
; 50(1): 1831-1842, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30803059
13.
Probenecid Reduces Alcohol Drinking in Rodents. Is Pannexin1 a Novel Therapeutic Target for Alcohol Use Disorder?
Alcohol Alcohol
; 54(5): 497-502, 2019 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31535696
14.
Genetic and Pharmacologic Manipulation of TLR4 Has Minimal Impact on Ethanol Consumption in Rodents.
J Neurosci
; 37(5): 1139-1155, 2017 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27986929
15.
Systemic Delivery of a Brain-Penetrant TrkB Antagonist Reduces Cocaine Self-Administration and Normalizes TrkB Signaling in the Nucleus Accumbens and Prefrontal Cortex.
J Neurosci
; 36(31): 8149-59, 2016 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27488635
16.
Recruitment of a Neuronal Ensemble in the Central Nucleus of the Amygdala Is Required for Alcohol Dependence.
J Neurosci
; 36(36): 9446-53, 2016 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27605618
17.
Chronic nicotine activates stress/reward-related brain regions and facilitates the transition to compulsive alcohol drinking.
J Neurosci
; 35(15): 6241-53, 2015 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25878294
18.
κ Opioid receptors in the nucleus accumbens shell mediate escalation of methamphetamine intake.
J Neurosci
; 35(10): 4296-305, 2015 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-25762676
19.
DNA methylation in the medial prefrontal cortex regulates alcohol-induced behavior and plasticity.
J Neurosci
; 35(15): 6153-64, 2015 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25878287
20.
Dynamic vaccine blocks relapse to compulsive intake of heroin.
Proc Natl Acad Sci U S A
; 110(22): 9036-41, 2013 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-23650354