RESUMO
A strain that produces new lipopeptide antibiotics is a new species of the genus Actinoplanes for which we propose the name Actinoplanes friuliensis (type strain: HAG 010964). The strain is an actinoplanete actinomycete having cell wall II composition and forming sporangia. Comparisons with Actinoplanes spp. which have similarities with our isolate, including fatty acid analysis, showed that the isolate belongs to a new species. Taxonomic studies and fermentation are presented.
Assuntos
Actinomycetales/classificação , Actinomycetales/metabolismo , Antibacterianos/farmacologia , Inibidores da Síntese de Proteínas/farmacologia , Actinomycetales/fisiologia , Antibacterianos/metabolismo , Avaliação Pré-Clínica de Medicamentos/métodos , Ácidos Graxos/metabolismo , Fermentação , Testes de Sensibilidade Microbiana , Peptidoglicano/biossíntese , Peptidoglicano/efeitos dos fármacos , Inibidores da Síntese de Proteínas/metabolismoRESUMO
Morphological characteristics, respiratory quinones, biochemical activities, cell wall ultrastructure and DNA base composition of Mycobacterium flavum 301 were studied. On the basis of the composition of its cell wall, its respiratory quinone and ubiquinone, the organism was associated with gram-negative bacteria. The strain appears to represent a group of bacteria hitherto not described.