Detalhe da pesquisa
1.
Discriminating cyclic from linear nucleotides - CRISPR/Cas-related cyclic hexaadenosine monophosphate as a case study.
Anal Biochem
; 567: 21-26, 2019 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30502320
2.
Identification of nicotinamide aminonaphthyridine compounds as potent RET kinase inhibitors and antitumor activities against RET rearranged lung adenocarcinoma.
Bioorg Chem
; 90: 103052, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31226468
3.
ENPP1, an Old Enzyme with New Functions, and Small Molecule Inhibitors-A STING in the Tale of ENPP1.
Molecules
; 24(22)2019 Nov 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31752288
4.
Development of an Iridium(III) Complex as a G-Quadruplex Probe and Its Application for the G-Quadruplex-Based Luminescent Detection of Picomolar Insulin.
Anal Chem
; 88(1): 981-7, 2016 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26607385
5.
Discovery of a small-molecule inhibitor of STAT3 by ligand-based pharmacophore screening.
Methods
; 71: 38-43, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25160651
6.
Detection of 3'â5' exonuclease activity using a metal-based luminescent switch-on probe.
Methods
; 64(3): 218-23, 2013 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23973810
7.
A parallel G-quadruplex-selective luminescent probe for the detection of nanomolar calcium(II) ion.
Methods
; 64(3): 212-7, 2013 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23876936
8.
A label-free G-quadruplex-based luminescent switch-on assay for the selective detection of histidine.
Methods
; 64(3): 205-11, 2013 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23891801
9.
Chloride Homeostasis Regulates cGAS-STING Signaling.
bioRxiv
; 2024 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38645072
10.
Proteomic and phosphoproteomic analyses of Jurkat T-cell treated with 2'3' cGAMP reveals various signaling axes impacted by cyclic dinucleotides.
J Proteomics
; 279: 104869, 2023 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36889538
11.
c-di-GMP Induces COX-2 Expression in Macrophages in a STING-Independent Manner.
ACS Chem Biol
; 16(9): 1663-1670, 2021 09 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34478263
12.
HSD1787, a Tetrahydro-3H-Pyrazolo[4,3-f]Quinoline Compound Synthesized via Povarov Reaction, Potently Inhibits Proliferation of Cancer Cell Lines at Nanomolar Concentrations.
ACS Omega
; 5(37): 23799-23807, 2020 Sep 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32984700
13.
Global Proteomic Analyses of STING-Positive and -Negative Macrophages Reveal STING and Non-STING Differentially Regulated Cellular and Molecular Pathways.
Proteomics Clin Appl
; 14(3): e1900109, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32065729
14.
Interrupting cyclic dinucleotide-cGAS-STING axis with small molecules.
Medchemcomm
; 10(12): 1999-2023, 2019 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32206239
15.
Inhibitors of Intracellular Gram-Positive Bacterial Growth Synthesized via Povarov-Doebner Reactions.
ACS Infect Dis
; 5(11): 1820-1830, 2019 11 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31512848
16.
Amino alkynylisoquinoline and alkynylnaphthyridine compounds potently inhibit acute myeloid leukemia proliferation in mice.
EBioMedicine
; 40: 231-239, 2019 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-30686755
17.
Suramin potently inhibits cGAMP synthase, cGAS, in THP1 cells to modulate IFN-ß levels.
Future Med Chem
; 10(11): 1301-1317, 2018 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29558821
18.
Rhodium complexes as therapeutic agents.
Dalton Trans
; 45(7): 2762-71, 2016 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26743935
19.
A novel dinuclear iridium(III) complex as a G-quadruplex-selective probe for the luminescent switch-on detection of transcription factor HIF-1α.
Sci Rep
; 6: 22458, 2016 Mar 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26932240
20.
A long lifetime switch-on iridium(III) chemosensor for the visualization of cysteine in live zebrafish.
Chem Commun (Camb)
; 52(24): 4450-3, 2016 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26899271