Pesquisa | BVS Violência e Saúde

1.

Anthracyclines induce cardiotoxicity through a shared gene expression response signature.

Matthews, E Renee; Johnson, Omar D; Horn, Kandace J; Gutiérrez, José A; Powell, Simon R; Ward, Michelle C.

PLoS Genet ; 20(2): e1011164, 2024 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-38416769

2.

Impact of regulatory variation across human iPSCs and differentiated cells.

Banovich, Nicholas E; Li, Yang I; Raj, Anil; Ward, Michelle C; Greenside, Peyton; Calderon, Diego; Tung, Po Yuan; Burnett, Jonathan E; Myrthil, Marsha; Thomas, Samantha M; Burrows, Courtney K; Romero, Irene Gallego; Pavlovic, Bryan J; Kundaje, Anshul; Pritchard, Jonathan K; Gilad, Yoav.

Genome Res ; 28(1): 122-131, 2018 01.

Artigo em Inglês | MEDLINE | ID: mdl-29208628

3.

Latent regulatory potential of human-specific repetitive elements.

Ward, Michelle C; Wilson, Michael D; Barbosa-Morais, Nuno L; Schmidt, Dominic; Stark, Rory; Pan, Qun; Schwalie, Petra C; Menon, Suraj; Lukk, Margus; Watt, Stephen; Thybert, David; Kutter, Claudia; Kirschner, Kristina; Flicek, Paul; Blencowe, Benjamin J; Odom, Duncan T.

Mol Cell ; 49(2): 262-72, 2013 Jan 24.

Artigo em Inglês | MEDLINE | ID: mdl-23246434

4.

Human genomics: Cracking the regulatory code.

Ward, Michelle C; Gilad, Yoav.

Nature ; 550(7675): 190-191, 2017 10 11.

Artigo em Inglês | MEDLINE | ID: mdl-29022577

5.

Insights into hominid evolution from the gorilla genome sequence.

Scally, Aylwyn; Dutheil, Julien Y; Hillier, LaDeana W; Jordan, Gregory E; Goodhead, Ian; Herrero, Javier; Hobolth, Asger; Lappalainen, Tuuli; Mailund, Thomas; Marques-Bonet, Tomas; McCarthy, Shane; Montgomery, Stephen H; Schwalie, Petra C; Tang, Y Amy; Ward, Michelle C; Xue, Yali; Yngvadottir, Bryndis; Alkan, Can; Andersen, Lars N; Ayub, Qasim; Ball, Edward V; Beal, Kathryn; Bradley, Brenda J; Chen, Yuan; Clee, Chris M; Fitzgerald, Stephen; Graves, Tina A; Gu, Yong; Heath, Paul; Heger, Andreas; Karakoc, Emre; Kolb-Kokocinski, Anja; Laird, Gavin K; Lunter, Gerton; Meader, Stephen; Mort, Matthew; Mullikin, James C; Munch, Kasper; O'Connor, Timothy D; Phillips, Andrew D; Prado-Martinez, Javier; Rogers, Anthony S; Sajjadian, Saba; Schmidt, Dominic; Shaw, Katy; Simpson, Jared T; Stenson, Peter D; Turner, Daniel J; Vigilant, Linda; Vilella, Albert J.

Nature ; 483(7388): 169-75, 2012 Mar 07.

Artigo em Inglês | MEDLINE | ID: mdl-22398555

6.

Deregulated LAP2α expression in cervical cancer associates with aberrant E2F and p53 activities.

Ward, Michelle C; van der Watt, Pauline J; Tzoneva, Gannie; Leaner, Virna D.

IUBMB Life ; 63(11): 1018-26, 2011 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-21990273

7.

Dynamic effects of genetic variation on gene expression revealed following hypoxic stress in cardiomyocytes.

Ward, Michelle C; Banovich, Nicholas E; Sarkar, Abhishek; Stephens, Matthew; Gilad, Yoav.

Elife ; 102021 02 08.

Artigo em Inglês | MEDLINE | ID: mdl-33554857

8.

Functional dynamic genetic effects on gene regulation are specific to particular cell types and environmental conditions.

Findley, Anthony S; Monziani, Alan; Richards, Allison L; Rhodes, Katherine; Ward, Michelle C; Kalita, Cynthia A; Alazizi, Adnan; Pazokitoroudi, Ali; Sankararaman, Sriram; Wen, Xiaoquan; Lanfear, David E; Pique-Regi, Roger; Gilad, Yoav; Luca, Francesca.

Elife ; 102021 05 14.

Artigo em Inglês | MEDLINE | ID: mdl-33988505

9.

A generally conserved response to hypoxia in iPSC-derived cardiomyocytes from humans and chimpanzees.

Ward, Michelle C; Gilad, Yoav.

Elife ; 82019 04 08.

Artigo em Inglês | MEDLINE | ID: mdl-30958265

10.

Association of Human iPSC Gene Signatures and X Chromosome Dosage with Two Distinct Cardiac Differentiation Trajectories.

D'Antonio-Chronowska, Agnieszka; Donovan, Margaret K R; Young Greenwald, William W; Nguyen, Jennifer Phuong; Fujita, Kyohei; Hashem, Sherin; Matsui, Hiroko; Soncin, Francesca; Parast, Mana; Ward, Michelle C; Coulet, Florence; Smith, Erin N; Adler, Eric; D'Antonio, Matteo; Frazer, Kelly A.

Stem Cell Reports ; 13(5): 924-938, 2019 11 12.

Artigo em Inglês | MEDLINE | ID: mdl-31668852

11.

Silencing of transposable elements may not be a major driver of regulatory evolution in primate iPSCs.

Ward, Michelle C; Zhao, Siming; Luo, Kaixuan; Pavlovic, Bryan J; Karimi, Mohammad M; Stephens, Matthew; Gilad, Yoav.

Elife ; 72018 04 12.

Artigo em Inglês | MEDLINE | ID: mdl-29648536

12.

Successful transmission and transcriptional deployment of a human chromosome via mouse male meiosis.

Ernst, Christina; Pike, Jeremy; Aitken, Sarah J; Long, Hannah K; Eling, Nils; Stojic, Lovorka; Ward, Michelle C; Connor, Frances; Rayner, Timothy F; Lukk, Margus; Klose, Robert J; Kutter, Claudia; Odom, Duncan T.

Elife ; 52016 11 18.

Artigo em Inglês | MEDLINE | ID: mdl-27855777

13.

A panel of induced pluripotent stem cells from chimpanzees: a resource for comparative functional genomics.

Gallego Romero, Irene; Pavlovic, Bryan J; Hernando-Herraez, Irene; Zhou, Xiang; Ward, Michelle C; Banovich, Nicholas E; Kagan, Courtney L; Burnett, Jonathan E; Huang, Constance H; Mitrano, Amy; Chavarria, Claudia I; Friedrich Ben-Nun, Inbar; Li, Yingchun; Sabatini, Karen; Leonardo, Trevor R; Parast, Mana; Marques-Bonet, Tomas; Laurent, Louise C; Loring, Jeanne F; Gilad, Yoav.

Elife ; 4: e07103, 2015 Jun 23.

Artigo em Inglês | MEDLINE | ID: mdl-26102527

14.

Co-binding by YY1 identifies the transcriptionally active, highly conserved set of CTCF-bound regions in primate genomes.

Schwalie, Petra C; Ward, Michelle C; Cain, Carolyn E; Faure, Andre J; Gilad, Yoav; Odom, Duncan T; Flicek, Paul.

Genome Biol ; 14(12): R148, 2013 Dec 31.

Artigo em Inglês | MEDLINE | ID: mdl-24380390

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