1.
2.
CMAJ
; 195(22): E786, 2023 06 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37277131
3.
Open Forum Infect Dis
; 8(7): ofab253, 2021 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34250191
RESUMO
Disseminated Mycobacterium avium complex (dMAC) is typically seen in individuals with impaired cell-mediated immunity and is best described in those with HIV. Recently, cases have been described in otherwise healthy individuals with neutralizing antibodies to interferon-gamma (nIFNγ-autoAb), especially in patients of Southeast Asian descent. Treatment is often refractory to mycobacterial therapies, and the use of rituximab and other immunomodulatory agents has been explored. We report 3 cases of dMAC with nIFN-γ-autoAb and review the available literature on treatment strategies to provide a framework for the management of patients with refractory infections in the context of neutralizing antibodies to interferon-gamma.
4.
CJEM
; 25(11): 858-861, 2023 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37580641
5.