Pesquisa | BVS Violência e Saúde

1.

A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds.

Bruna, Alejandra; Rueda, Oscar M; Greenwood, Wendy; Batra, Ankita Sati; Callari, Maurizio; Batra, Rajbir Nath; Pogrebniak, Katherine; Sandoval, Jose; Cassidy, John W; Tufegdzic-Vidakovic, Ana; Sammut, Stephen-John; Jones, Linda; Provenzano, Elena; Baird, Richard; Eirew, Peter; Hadfield, James; Eldridge, Matthew; McLaren-Douglas, Anne; Barthorpe, Andrew; Lightfoot, Howard; O'Connor, Mark J; Gray, Joe; Cortes, Javier; Baselga, Jose; Marangoni, Elisabetta; Welm, Alana L; Aparicio, Samuel; Serra, Violeta; Garnett, Mathew J; Caldas, Carlos.

Cell ; 167(1): 260-274.e22, 2016 09 22.

Artigo em Inglês | MEDLINE | ID: mdl-27641504

2.

Tumoural activation of TLR3-SLIT2 axis in endothelium drives metastasis.

Tavora, Bernardo; Mederer, Tobias; Wessel, Kai J; Ruffing, Simon; Sadjadi, Mahan; Missmahl, Marc; Ostendorf, Benjamin N; Liu, Xuhang; Kim, Ji-Young; Olsen, Olav; Welm, Alana L; Goodarzi, Hani; Tavazoie, Sohail F.

Nature ; 586(7828): 299-304, 2020 10.

Artigo em Inglês | MEDLINE | ID: mdl-32999457

3.

Research autopsy programmes in oncology: shared experience from 14 centres across the world.

Geukens, Tatjana; Maetens, Marion; Hooper, Jody E; Oesterreich, Steffi; Lee, Adrian V; Miller, Lori; Atkinson, Jenny M; Rosenzweig, Margaret; Puhalla, Shannon; Thorne, Heather; Devereux, Lisa; Bowtell, David; Loi, Sherene; Bacon, Eliza R; Ihle, Kena; Song, Mihae; Rodriguez-Rodriguez, Lorna; Welm, Alana L; Gauchay, Lisa; Murali, Rajmohan; Chanda, Pharto; Karacay, Ali; Naceur-Lombardelli, Cristina; Bridger, Hayley; Swanton, Charles; Jamal-Hanjani, Mariam; Kollath, Lori; True, Lawrence; Morrissey, Colm; Chambers, Meagan; Chinnaiyan, Arul M; Wilson, Allecia; Mehra, Rohit; Reichert, Zachery; Carey, Lisa A; Perou, Charles M; Kelly, Erin; Maeda, Daichi; Goto, Akiteru; Kulka, Janina; Székely, Borbála; Szasz, A Marcell; Tokés, Anna-Mária; Van Den Bogaert, Wouter; Floris, Giuseppe; Desmedt, Christine.

J Pathol ; 263(2): 150-165, 2024 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-38551513

4.

TGFbeta primes breast tumor cells for metastasis.

Welm, Alana L.

Cell ; 133(1): 27-8, 2008 Apr 04.

Artigo em Inglês | MEDLINE | ID: mdl-18394984

5.

An immune-humanized patient-derived xenograft model of estrogen-independent, hormone receptor positive metastatic breast cancer.

Scherer, Sandra D; Riggio, Alessandra I; Haroun, Fadi; DeRose, Yoko S; Ekiz, H Atakan; Fujita, Maihi; Toner, Jennifer; Zhao, Ling; Li, Zheqi; Oesterreich, Steffi; Samatar, Ahmed A; Welm, Alana L.

Breast Cancer Res ; 23(1): 100, 2021 10 30.

Artigo em Inglês | MEDLINE | ID: mdl-34717714

6.

Evaluation of FGFR targeting in breast cancer through interrogation of patient-derived models.

Chew, Nicole J; Lim Kam Sian, Terry C C; Nguyen, Elizabeth V; Shin, Sung-Young; Yang, Jessica; Hui, Mun N; Deng, Niantao; McLean, Catriona A; Welm, Alana L; Lim, Elgene; Gregory, Peter; Nottle, Tim; Lang, Tali; Vereker, Melissa; Richardson, Gary; Kerr, Genevieve; Micati, Diana; Jardé, Thierry; Abud, Helen E; Lee, Rachel S; Swarbrick, Alex; Daly, Roger J.

Breast Cancer Res ; 23(1): 82, 2021 08 03.

Artigo em Inglês | MEDLINE | ID: mdl-34344433

7.

The lingering mysteries of metastatic recurrence in breast cancer.

Riggio, Alessandra I; Varley, Katherine E; Welm, Alana L.

Br J Cancer ; 124(1): 13-26, 2021 01.

Artigo em Inglês | MEDLINE | ID: mdl-33239679

8.

RON signalling promotes therapeutic resistance in ESR1 mutant breast cancer.

Dustin, Derek; Gu, Guowei; Beyer, Amanda R; Herzog, Sarah K; Edwards, David G; Lin, Hangqing; Gonzalez, Thomas L; Grimm, Sandra L; Coarfa, Cristian; Chan, Doug W; Kim, Beom-Jun; De La O, Jean-Paul; Ellis, Matthew J; Liu, Dan; Li, Shunqiang; Welm, Alana L; Fuqua, Suzanne A W.

Br J Cancer ; 124(1): 191-206, 2021 01.

Artigo em Inglês | MEDLINE | ID: mdl-33257837

9.

Enrichment of Collagen Fragments Using Dimeric Collagen Hybridizing Peptide for Urinary Collagenomics.

Kessler, Julian L; Li, Yang; Fornetti, Jaime; Welm, Alana L; Yu, S Michael.

J Proteome Res ; 19(8): 2926-2932, 2020 08 07.

Artigo em Inglês | MEDLINE | ID: mdl-32500704

10.

Navitoclax enhances the effectiveness of EGFR-targeted antibody-drug conjugates in PDX models of EGFR-expressing triple-negative breast cancer.

Zoeller, Jason J; Vagodny, Aleksandr; Daniels, Veerle W; Taneja, Krishan; Tan, Benjamin Y; DeRose, Yoko S; Fujita, Maihi; Welm, Alana L; Letai, Anthony; Leverson, Joel D; Blot, Vincent; Bronson, Roderick T; Dillon, Deborah A; Brugge, Joan S.

Breast Cancer Res ; 22(1): 132, 2020 11 30.

Artigo em Inglês | MEDLINE | ID: mdl-33256808

11.

Epigenetic silencing of TGFBI confers resistance to trastuzumab in human breast cancer.

Palomeras, Sònia; Diaz-Lagares, Ángel; Viñas, Gemma; Setien, Fernando; Ferreira, Humberto J; Oliveras, Glòria; Crujeiras, Ana B; Hernández, Alejandro; Lum, David H; Welm, Alana L; Esteller, Manel; Puig, Teresa.

Breast Cancer Res ; 21(1): 79, 2019 07 05.

Artigo em Inglês | MEDLINE | ID: mdl-31277676

12.

Metabolic reprogramming in triple-negative breast cancer through Myc suppression of TXNIP.

Shen, Liangliang; O'Shea, John M; Kaadige, Mohan R; Cunha, Stéphanie; Wilde, Blake R; Cohen, Adam L; Welm, Alana L; Ayer, Donald E.

Proc Natl Acad Sci U S A ; 112(17): 5425-30, 2015 Apr 28.

Artigo em Inglês | MEDLINE | ID: mdl-25870263

13.

Plasma exosome microRNAs are indicative of breast cancer.

Hannafon, Bethany N; Trigoso, Yvonne D; Calloway, Cameron L; Zhao, Y Daniel; Lum, David H; Welm, Alana L; Zhao, Zhizhuang J; Blick, Kenneth E; Dooley, William C; Ding, W Q.

Breast Cancer Res ; 18(1): 90, 2016 09 08.

Artigo em Inglês | MEDLINE | ID: mdl-27608715

14.

On the shoulders of giants: a historical perspective of unique experimental methods in mammary gland research.

Smith, Brittni A; Welm, Alana L; Welm, Bryan E.

Semin Cell Dev Biol ; 23(5): 583-90, 2012 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-22425744

15.

Breast Cancer Immunity: It is TIME for the Next Chapter.

Quail, Daniela F; Park, Morag; Welm, Alana L; Ekiz, H Atakan.

Cold Spring Harb Perspect Med ; 14(2)2024 Feb 01.

Artigo em Inglês | MEDLINE | ID: mdl-37188526

16.

Immune evasion of dormant disseminated tumor cells is due to their scarcity and can be overcome by T cell immunotherapies.

Goddard, Erica T; Linde, Miles H; Srivastava, Shivani; Klug, Grant; Shabaneh, Tamer B; Iannone, Santino; Grzelak, Candice A; Marsh, Sydney; Riggio, Alessandra I; Shor, Ryann E; Linde, Ian L; Guerrero, Marissa; Veatch, Joshua R; Snyder, Annelise G; Welm, Alana L; Riddell, Stanley R; Ghajar, Cyrus M.

Cancer Cell ; 42(1): 119-134.e12, 2024 01 08.

Artigo em Inglês | MEDLINE | ID: mdl-38194912

17.

Assessment of Patient-Derived Xenograft Growth and Antitumor Activity: The NCI PDXNet Consensus Recommendations.

Meric-Bernstam, Funda; Lloyd, Michael W; Koc, Soner; Evrard, Yvonne A; McShane, Lisa Meier; Lewis, Michael T; Evans, Kurt W; Li, Dali; Rubinstein, Lawrence V; Welm, Alana L; Dean, Dennis A; Srivastava, Anuj; Grover, Jeffrey W; Ha, Min Jin; Chen, Huiqin; Huang, Xuelin; Varadarajan, Kaushik; Wang, Jing; Roth, Jack A; Welm, Bryan E; Govindan, Ramaswamy; Ding, Li; Kaochar, Salma; Mitsiades, Nicholas; Carvajal-Carmona, Luis G; Herlyn, Meenhard; Davies, Michael A; Shapiro, Geoffrey I; Fields, Ryan C; Trevino, Jose G; Harrell, J Chuck; Doroshow, James H; Chuang, Jeffrey H; Moscow, Jeffrey A.

Mol Cancer Ther ; 2024 Apr 20.

Artigo em Inglês | MEDLINE | ID: mdl-38641411

18.

Survivin promotion of melanoma metastasis requires upregulation of α5 integrin.

McKenzie, Jodi A; Liu, Tong; Jung, Jae Y; Jones, Benjamin B; Ekiz, Huseyin A; Welm, Alana L; Grossman, Douglas.

Carcinogenesis ; 34(9): 2137-44, 2013 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-23640047

19.

Mouse models of breast cancer metastasis to bone.

Kretschmann, Kelsi L; Welm, Alana L.

Cancer Metastasis Rev ; 31(3-4): 579-83, 2012 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-22706780

20.

Netrin-4 activates endothelial integrin {alpha}6{beta}1.

Larrieu-Lahargue, Frederic; Welm, Alana L; Thomas, Kirk R; Li, Dean Y.

Circ Res ; 109(7): 770-4, 2011 Sep 16.

Artigo em Inglês | MEDLINE | ID: mdl-21799154

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