Pesquisa | BVS Violência e Saúde

1.

The Oncogenic Action of NRF2 Depends on De-glycation by Fructosamine-3-Kinase.

Sanghvi, Viraj R; Leibold, Josef; Mina, Marco; Mohan, Prathibha; Berishaj, Marjan; Li, Zhuoning; Miele, Matthew M; Lailler, Nathalie; Zhao, Chunying; de Stanchina, Elisa; Viale, Agnes; Akkari, Leila; Lowe, Scott W; Ciriello, Giovanni; Hendrickson, Ronald C; Wendel, Hans-Guido.

Cell ; 178(4): 807-819.e21, 2019 08 08.

Artigo em Inglês | MEDLINE | ID: mdl-31398338

2.

Loss of the HVEM Tumor Suppressor in Lymphoma and Restoration by Modified CAR-T Cells.

Boice, Michael; Salloum, Darin; Mourcin, Frederic; Sanghvi, Viraj; Amin, Rada; Oricchio, Elisa; Jiang, Man; Mottok, Anja; Denis-Lagache, Nicolas; Ciriello, Giovanni; Tam, Wayne; Teruya-Feldstein, Julie; de Stanchina, Elisa; Chan, Wing C; Malek, Sami N; Ennishi, Daisuke; Brentjens, Renier J; Gascoyne, Randy D; Cogné, Michel; Tarte, Karin; Wendel, Hans-Guido.

Cell ; 167(2): 405-418.e13, 2016 Oct 06.

Artigo em Inglês | MEDLINE | ID: mdl-27693350

3.

The Eph-receptor A7 is a soluble tumor suppressor for follicular lymphoma.

Oricchio, Elisa; Nanjangud, Gouri; Wolfe, Andrew L; Schatz, Jonathan H; Mavrakis, Konstantinos J; Jiang, Man; Liu, Xiaoping; Bruno, Joanne; Heguy, Adriana; Olshen, Adam B; Socci, Nicholas D; Teruya-Feldstein, Julie; Weis-Garcia, Frances; Tam, Wayne; Shaknovich, Rita; Melnick, Ari; Himanen, Juha P; Chaganti, R S K; Wendel, Hans-Guido.

Cell ; 147(3): 554-64, 2011 Oct 28.

Artigo em Inglês | MEDLINE | ID: mdl-22036564

4.

A Rapid Translational Immune Response Program in CD8 Memory T Lymphocytes.

Salloum, Darin; Singh, Kamini; Davidson, Natalie R; Cao, Linlin; Kuo, David; Sanghvi, Viraj R; Jiang, Man; Lafoz, Maria Tello; Viale, Agnes; Ratsch, Gunnar; Wendel, Hans-Guido.

J Immunol ; 209(6): 1189-1199, 2022 09 15.

Artigo em Inglês | MEDLINE | ID: mdl-36002234

5.

Comparing the Effects of Rocaglates on Energy Metabolism and Immune Modulation on Cells of the Human Immune System.

Schiffmann, Susanne; Henke, Marina; Seifert, Michelle; Ulshöfer, Thomas; Roser, Luise A; Magari, Francesca; Wendel, Hans-Guido; Grünweller, Arnold; Parnham, Michael J.

Int J Mol Sci ; 24(6)2023 Mar 20.

Artigo em Inglês | MEDLINE | ID: mdl-36982945

6.

NOXA genetic amplification or pharmacologic induction primes lymphoma cells to BCL2 inhibitor-induced cell death.

Liu, Yuxuan; Mondello, Patrizia; Erazo, Tatiana; Tannan, Neeta Bala; Asgari, Zahra; de Stanchina, Elisa; Nanjangud, Gouri; Seshan, Venkatraman E; Wang, Shenqiu; Wendel, Hans-Guido; Younes, Anas.

Proc Natl Acad Sci U S A ; 115(47): 12034-12039, 2018 11 20.

Artigo em Inglês | MEDLINE | ID: mdl-30404918

7.

The cat-and-mouse game of BTK inhibition.

Portelinha, Ana; Wendel, Hans-Guido.

Blood ; 141(13): 1502-1503, 2023 03 30.

Artigo em Inglês | MEDLINE | ID: mdl-36995705

8.

RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer.

Wolfe, Andrew L; Singh, Kamini; Zhong, Yi; Drewe, Philipp; Rajasekhar, Vinagolu K; Sanghvi, Viraj R; Mavrakis, Konstantinos J; Jiang, Man; Roderick, Justine E; Van der Meulen, Joni; Schatz, Jonathan H; Rodrigo, Christina M; Zhao, Chunying; Rondou, Pieter; de Stanchina, Elisa; Teruya-Feldstein, Julie; Kelliher, Michelle A; Speleman, Frank; Porco, John A; Pelletier, Jerry; Rätsch, Gunnar; Wendel, Hans-Guido.

Nature ; 513(7516): 65-70, 2014 Sep 04.

Artigo em Inglês | MEDLINE | ID: mdl-25079319

9.

Targeted PET imaging strategy to differentiate malignant from inflamed lymph nodes in diffuse large B-cell lymphoma.

Tang, Jun; Salloum, Darin; Carney, Brandon; Brand, Christian; Kossatz, Susanne; Sadique, Ahmad; Lewis, Jason S; Weber, Wolfgang A; Wendel, Hans-Guido; Reiner, Thomas.

Proc Natl Acad Sci U S A ; 114(36): E7441-E7449, 2017 09 05.

Artigo em Inglês | MEDLINE | ID: mdl-28827325

10.

RiboDiff: detecting changes of mRNA translation efficiency from ribosome footprints.

Zhong, Yi; Karaletsos, Theofanis; Drewe, Philipp; Sreedharan, Vipin T; Kuo, David; Singh, Kamini; Wendel, Hans-Guido; Rätsch, Gunnar.

Bioinformatics ; 33(1): 139-141, 2017 01 01.

Artigo em Inglês | MEDLINE | ID: mdl-27634950

11.

The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia.

Van der Meulen, Joni; Sanghvi, Viraj; Mavrakis, Konstantinos; Durinck, Kaat; Fang, Fang; Matthijssens, Filip; Rondou, Pieter; Rosen, Monica; Pieters, Tim; Vandenberghe, Peter; Delabesse, Eric; Lammens, Tim; De Moerloose, Barbara; Menten, Björn; Van Roy, Nadine; Verhasselt, Bruno; Poppe, Bruce; Benoit, Yves; Taghon, Tom; Melnick, Ari M; Speleman, Frank; Wendel, Hans-Guido; Van Vlierberghe, Pieter.

Blood ; 125(1): 13-21, 2015 Jan 01.

Artigo em Inglês | MEDLINE | ID: mdl-25320243

12.

Forward genetic screens in mice uncover mediators and suppressors of metastatic reactivation.

Gao, Hua; Chakraborty, Goutam; Lee-Lim, Ai Ping; Mavrakis, Konstantinos J; Wendel, Hans-Guido; Giancotti, Filippo G.

Proc Natl Acad Sci U S A ; 111(46): 16532-7, 2014 Nov 18.

Artigo em Inglês | MEDLINE | ID: mdl-25378704

13.

Emerging therapeutic targets in follicular lymphoma.

Wendel, Hans-Guido.

Clin Adv Hematol Oncol ; 18(1): 32-34, 2020 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-32511220

14.

Generation and characterization of a single-chain anti-EphA2 antibody.

Goldgur, Yehuda; Susi, Petri; Karelehto, Eveliina; Sanmark, Hanna; Lamminmäki, Urpo; Oricchio, Elisa; Wendel, Hans-Guido; Nikolov, Dimitar B; Himanen, Juha P.

Growth Factors ; 32(6): 214-22, 2014 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-25494541

15.

MicroRNA-128-3p is a novel oncomiR targeting PHF6 in T-cell acute lymphoblastic leukemia.

Mets, Evelien; Van Peer, Gert; Van der Meulen, Joni; Boice, Michael; Taghon, Tom; Goossens, Steven; Mestdagh, Pieter; Benoit, Yves; De Moerloose, Barbara; Van Roy, Nadine; Poppe, Bruce; Vandesompele, Jo; Wendel, Hans-Guido; Van Vlierberghe, Pieter; Speleman, Frank; Rondou, Pieter.

Haematologica ; 99(8): 1326-33, 2014 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-24895337

16.

eIF4A controls translation of estrogen receptor alpha and is a therapeutic target in advanced breast cancer.

Boyer, Jacob A; Sharma, Malvika; Dorso, Madeline A; Mai, Nicholas; Amor, Corina; Reiter, Jason M; Kannan, Ram; Gadal, Sunyana; Xu, Jianing; Miele, Matthew; Li, Zhuoning; Chen, Xiaoping; Chang, Qing; Pareja, Fresia; Worland, Stephan; Warner, Douglas; Sperry, Sam; Chiang, Gary G; Thompson, Peggy A; Yang, Guangli; Ouerfelli, Ouathek; de Stanchina, Elisa; Wendel, Hans-Guido; Rosen, Ezra Y; Chandarlapaty, Sarat; Rosen, Neal.

bioRxiv ; 2024 May 11.

Artigo em Inglês | MEDLINE | ID: mdl-38766126

17.

Synthetic lethality of drug-induced polyploidy and BCL-2 inhibition in lymphoma.

Portelinha, Ana; da Silva Ferreira, Mariana; Erazo, Tatiana; Jiang, Man; Asgari, Zahra; de Stanchina, Elisa; Younes, Anas; Wendel, Hans-Guido.

Nat Commun ; 14(1): 1522, 2023 03 18.

Artigo em Inglês | MEDLINE | ID: mdl-36934096

18.

Rapamycin-Induced Feedback Activation of eIF4E-EIF4A Dependent mRNA Translation in Pancreatic Cancer.

Nguyen, Trang Uyen; Hector, Harrison; Pederson, Eric Nels; Lin, Jianan; Ouyang, Zhengqing; Wendel, Hans-Guido; Singh, Kamini.

Cancers (Basel) ; 15(5)2023 Feb 24.

Artigo em Inglês | MEDLINE | ID: mdl-36900235

19.

Frequent 4EBP1 Amplification Induces Synthetic Dependence on FGFR Signaling in Cancer.

Mohan, Prathibha; Pasion, Joyce; Ciriello, Giovanni; Lailler, Nathalie; de Stanchina, Elisa; Viale, Agnes; van den Berg, Anke; Diepstra, Arjan; Wendel, Hans-Guido; Sanghvi, Viraj R; Singh, Kamini.

Cancers (Basel) ; 14(10)2022 May 13.

Artigo em Inglês | MEDLINE | ID: mdl-35626002

20.

Rocaglates as Antivirals: Comparing the Effects on Viral Resistance, Anti-Coronaviral Activity, RNA-Clamping on eIF4A and Immune Cell Toxicity.

Obermann, Wiebke; Friedrich, Alexandra; Madhugiri, Ramakanth; Klemm, Paul; Mengel, Jan Philipp; Hain, Torsten; Pleschka, Stephan; Wendel, Hans-Guido; Hartmann, Roland K; Schiffmann, Susanne; Ziebuhr, John; Müller, Christin; Grünweller, Arnold.

Viruses ; 14(3)2022 03 03.

Artigo em Inglês | MEDLINE | ID: mdl-35336926

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