Pesquisa | BVS Violência e Saúde

1.

Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization.

Sullivan, William J; Mullen, Peter J; Schmid, Ernst W; Flores, Aimee; Momcilovic, Milica; Sharpley, Mark S; Jelinek, David; Whiteley, Andrew E; Maxwell, Matthew B; Wilde, Blake R; Banerjee, Utpal; Coller, Hilary A; Shackelford, David B; Braas, Daniel; Ayer, Donald E; de Aguiar Vallim, Thomas Q; Lowry, William E; Christofk, Heather R.

Cell ; 175(1): 117-132.e21, 2018 09 20.

Artigo em Inglês | MEDLINE | ID: mdl-30197082

2.

O-Mg! Lactate Drives Mg²⁺ Mobilization.

Wilde, Blake R; Christofk, Heather R.

Mol Cell ; 80(5): 762-763, 2020 12 03.

Artigo em Inglês | MEDLINE | ID: mdl-33275887

3.

TXNIP loss expands Myc-dependent transcriptional programs by increasing Myc genomic binding.

Lim, Tian-Yeh; Wilde, Blake R; Thomas, Mallory L; Murphy, Kristin E; Vahrenkamp, Jeffery M; Conway, Megan E; Varley, Katherine E; Gertz, Jason; Ayer, Donald E.

PLoS Biol ; 21(3): e3001778, 2023 03.

Artigo em Inglês | MEDLINE | ID: mdl-36930677

4.

Fumarate hydratase variant prevalence and manifestations among individuals receiving germline testing.

Lu, Eric; Hatchell, Kathryn E; Nielsen, Sarah M; Esplin, Edward D; Ouyang, Karen; Nykamp, Keith; Zavoshi, Shirin; Li, Shantao; Zhang, Liying; Wilde, Blake R; Christofk, Heather R; Boutros, Paul C; Shuch, Brian.

Cancer ; 128(4): 675-684, 2022 02 15.

Artigo em Inglês | MEDLINE | ID: mdl-34724198

5.

Metabolic reprogramming in triple-negative breast cancer through Myc suppression of TXNIP.

Shen, Liangliang; O'Shea, John M; Kaadige, Mohan R; Cunha, Stéphanie; Wilde, Blake R; Cohen, Adam L; Welm, Alana L; Ayer, Donald E.

Proc Natl Acad Sci U S A ; 112(17): 5425-30, 2015 Apr 28.

Artigo em Inglês | MEDLINE | ID: mdl-25870263

6.

Interactions between Myc and MondoA transcription factors in metabolism and tumourigenesis.

Wilde, Blake R; Ayer, Donald E.

Br J Cancer ; 113(11): 1529-33, 2015 Dec 01.

Artigo em Inglês | MEDLINE | ID: mdl-26469830

7.

FH Variant Pathogenicity Promotes Purine Salvage Pathway Dependence in Kidney Cancer.

Wilde, Blake R; Chakraborty, Nishma; Matulionis, Nedas; Hernandez, Stephanie; Ueno, Daiki; Gee, Michayla E; Esplin, Edward D; Ouyang, Karen; Nykamp, Keith; Shuch, Brian; Christofk, Heather R.

Cancer Discov ; 13(9): 2072-2089, 2023 09 06.

Artigo em Inglês | MEDLINE | ID: mdl-37255402

8.

ZFP36-mediated mRNA decay regulates metabolism.

Cicchetto, Andrew C; Jacobson, Elsie C; Sunshine, Hannah; Wilde, Blake R; Krall, Abigail S; Jarrett, Kelsey E; Sedgeman, Leslie; Turner, Martin; Plath, Kathrin; Iruela-Arispe, M Luisa; de Aguiar Vallim, Thomas Q; Christofk, Heather R.

Cell Rep ; 42(5): 112411, 2023 05 30.

Artigo em Inglês | MEDLINE | ID: mdl-37086408

9.

Protein synthesis inhibitors stimulate MondoA transcriptional activity by driving an accumulation of glucose 6-phosphate.

Wilde, Blake R; Kaadige, Mohan R; Guillen, Katrin P; Butterfield, Andrew; Welm, Bryan E; Ayer, Donald E.

Cancer Metab ; 8(1): 27, 2020 Dec 04.

Artigo em Inglês | MEDLINE | ID: mdl-33292639

10.

Cellular acidosis triggers human MondoA transcriptional activity by driving mitochondrial ATP production.

Wilde, Blake R; Ye, Zhizhou; Lim, Tian-Yeh; Ayer, Donald E.

Elife ; 82019 02 05.

Artigo em Inglês | MEDLINE | ID: mdl-30717828

11.

MondoA-Mlx transcriptional activity is limited by mTOR-MondoA interaction.

Kaadige, Mohan R; Yang, Jingye; Wilde, Blake R; Ayer, Donald E.

Mol Cell Biol ; 35(1): 101-10, 2015 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-25332233

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