Detalhe da pesquisa
1.
Successful therapeutic intervention in new mouse models of frizzled 2-associated congenital malformations.
Development
; 150(3)2023 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36789910
2.
Wnt5a promotes Frizzled-4 signalosome assembly by stabilizing cysteine-rich domain dimerization.
Genes Dev
; 31(9): 916-926, 2017 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28546512
3.
Low-Density Lipoprotein Receptor-Related Proteins in Skeletal Development and Disease.
Physiol Rev
; 97(3): 1211-1228, 2017 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28615463
4.
Endometrial hyperplasia with loss of APC in a novel population of Lyz2-expressing mouse endometrial epithelial cells.
Carcinogenesis
; 44(1): 54-64, 2023 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36548952
5.
Surrogate Wnt agonists that phenocopy canonical Wnt and ß-catenin signalling.
Nature
; 545(7653): 234-237, 2017 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28467818
6.
An osteocalcin-deficient mouse strain without endocrine abnormalities.
PLoS Genet
; 16(5): e1008361, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32463812
7.
Regulation of Wnt receptor activity: Implications for therapeutic development in colon cancer.
J Biol Chem
; 296: 100782, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34000297
8.
Structure and function of the retina of low-density lipoprotein receptor-related protein 5 (Lrp5)-deficient rats.
Exp Eye Res
; 217: 108977, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35139333
9.
LDL receptor-related protein LRP6 senses nutrient levels and regulates Hippo signaling.
EMBO Rep
; 21(9): e50103, 2020 09 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32767654
10.
Structure and function of Norrin in assembly and activation of a Frizzled 4-Lrp5/6 complex.
Genes Dev
; 27(21): 2305-19, 2013 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24186977
11.
Frizzled-4 is required for normal bone acquisition despite compensation by Frizzled-8.
J Cell Physiol
; 235(10): 6673-6683, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31985040
12.
Loss of Lgals3 Protects Against Gonadectomy-Induced Cortical Bone Loss in Mice.
Calcif Tissue Int
; 106(3): 283-293, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31745588
13.
A quest for clarity in bone erosion: The role of sequestosome 1 in Paget's disease of bone.
J Biol Chem
; 293(24): 9542-9543, 2018 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29907733
14.
Sclt1 deficiency causes cystic kidney by activating ERK and STAT3 signaling.
Hum Mol Genet
; 26(15): 2949-2960, 2017 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28486600
15.
Independent validation of experimental results requires timely and unrestricted access to animal models and reagents.
PLoS Genet
; 16(6): e1008940, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32589665
16.
Stroma provides an intestinal stem cell niche in the absence of epithelial Wnts.
Development
; 141(11): 2206-15, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24821987
17.
Vascular smooth muscle LRP6 limits arteriosclerotic calcification in diabetic LDLR-/- mice by restraining noncanonical Wnt signals.
Circ Res
; 117(2): 142-56, 2015 Jul 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26034040
18.
Regulation of angiogenesis by a non-canonical Wnt-Flt1 pathway in myeloid cells.
Nature
; 474(7352): 511-5, 2011 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-21623369
19.
Wnt Signaling in Ewing Sarcoma, Osteosarcoma, and Malignant Peripheral Nerve Sheath Tumors.
Curr Osteoporos Rep
; 15(4): 239-246, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28647886
20.
Cartilage-specific deletion of Mig-6 results in osteoarthritis-like disorder with excessive articular chondrocyte proliferation.
Proc Natl Acad Sci U S A
; 111(7): 2590-5, 2014 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24550287