Pesquisa | BVS Violência e Saúde

1.

Impact of Decalcification, Cold Ischemia, and Deglycosylation on Performance of Programmed Cell Death Ligand-1 Antibodies With Different Binding Epitopes: Comparison of 7 Clones.

Lawson, Nicola L; Scorer, Paul W; Williams, Gareth H; Vandenberghe, Michel E; Ratcliffe, Marianne J; Barker, Craig.

Mod Pathol ; 36(9): 100220, 2023 09.

Artigo em Inglês | MEDLINE | ID: mdl-37230414

2.

Mapping the binding sites of antibodies utilized in programmed cell death ligand-1 predictive immunohistochemical assays for use with immuno-oncology therapies.

Lawson, Nicola L; Dix, Carly I; Scorer, Paul W; Stubbs, Christopher J; Wong, Edmond; Hutchinson, Liam; McCall, Eileen J; Schimpl, Marianne; DeVries, Emma; Walker, Jill; Williams, Gareth H; Hunt, James; Barker, Craig.

Mod Pathol ; 33(4): 518-530, 2020 04.

Artigo em Inglês | MEDLINE | ID: mdl-31558782

3.

Correction: Mapping the binding sites of antibodies utilized in programmed cell death ligand-1 predictive immunohistochemical assays for use with immuno-oncology therapies.

Lawson, Nicola L; Dix, Carly I; Scorer, Paul W; Stubbs, Christopher J; Wong, Edmond; Hutchinson, Liam; McCall, Eileen J; Schimpl, Marianne; DeVries, Emma; Walker, Jill; Williams, Gareth H; Hunt, James; Barker, Craig.

Mod Pathol ; 33(4): 758, 2020 04.

Artigo em Inglês | MEDLINE | ID: mdl-31641230

4.

Immunophenotypic analysis of cell cycle status in acute myeloid leukaemia: relationship to cytogenetics, genotype and clinical outcome.

Sellar, Rob S; Gale, Rosemary E; Khwaja, Asim; Garbowski, Maciej; Loddo, Marco; Stoeber, Kai; Williams, Gareth H; Linch, David C.

Br J Haematol ; 181(4): 486-494, 2018 05.

Artigo em Inglês | MEDLINE | ID: mdl-29676467

5.

Molecular architecture of the DNA replication origin activation checkpoint.

Tudzarova, Slavica; Trotter, Matthew W B; Wollenschlaeger, Alex; Mulvey, Claire; Godovac-Zimmermann, Jasminka; Williams, Gareth H; Stoeber, Kai.

EMBO J ; 29(19): 3381-94, 2010 Oct 06.

Artigo em Inglês | MEDLINE | ID: mdl-20729811

6.

Cell cycle markers in clinical oncology.

Williams, Gareth H; Stoeber, Kai.

Curr Opin Cell Biol ; 19(6): 672-9, 2007 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-18032010

7.

Two ubiquitin ligases, APC/C-Cdh1 and SKP1-CUL1-F (SCF)-beta-TrCP, sequentially regulate glycolysis during the cell cycle.

Tudzarova, Slavica; Colombo, Sergio L; Stoeber, Kai; Carcamo, Saul; Williams, Gareth H; Moncada, Salvador.

Proc Natl Acad Sci U S A ; 108(13): 5278-83, 2011 Mar 29.

Artigo em Inglês | MEDLINE | ID: mdl-21402913

8.

Subcellular proteomics reveals a role for nucleo-cytoplasmic trafficking at the DNA replication origin activation checkpoint.

Mulvey, Claire M; Tudzarova, Slavica; Crawford, Mark; Williams, Gareth H; Stoeber, Kai; Godovac-Zimmermann, Jasminka.

J Proteome Res ; 12(3): 1436-53, 2013 Mar 01.

Artigo em Inglês | MEDLINE | ID: mdl-23320540

9.

The cell cycle and cancer.

Williams, Gareth H; Stoeber, Kai.

J Pathol ; 226(2): 352-64, 2012 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-21990031

10.

Making sense: further studies of living with chronic illness.

Williams, Gareth H; Jones, Ian Rees.

Sociol Health Illn ; 39(5): 653-658, 2017 06.

Artigo em Inglês | MEDLINE | ID: mdl-28627721

11.

Targeting DNA replication before it starts: Cdc7 as a therapeutic target in p53-mutant breast cancers.

Rodriguez-Acebes, Sara; Proctor, Ian; Loddo, Marco; Wollenschlaeger, Alex; Rashid, Mohammed; Falzon, Mary; Prevost, A Toby; Sainsbury, Richard; Stoeber, Kai; Williams, Gareth H.

Am J Pathol ; 177(4): 2034-45, 2010 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-20724597

12.

SARS-CoV-2 testing and sequencing for international arrivals reveals significant cross border transmission of high risk variants into the United Kingdom.

Williams, Gareth H; Llewelyn, Alexander; Brandao, Ruben; Chowdhary, Kaiya; Hardisty, Keeda-Marie; Loddo, Marco.

EClinicalMedicine ; 38: 101021, 2021 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-34278277

13.

Clinical, Radiometabolic and Immunologic Effects of Olaparib in Locally Advanced Triple Negative Breast Cancer: The OLTRE Window of Opportunity Trial.

Schettini, Francesco; Corona, Silvia Paola; Giudici, Fabiola; Strina, Carla; Sirico, Marianna; Bernocchi, Ottavia; Milani, Manuela; Ziglioli, Nicoletta; Aguggini, Sergio; Azzini, Carlo; Barbieri, Giuseppina; Cervoni, Valeria; Cappelletti, Maria Rosa; Molteni, Alfredo; Lazzari, Maria Chiara; Ferrero, Giuseppina; Ungari, Marco; Marasco, Elena; Bruson, Alice; Xumerle, Luciano; Zago, Elisa; Cerra, Davide; Loddo, Marco; Williams, Gareth H; Paris, Ida; Scambia, Giovanni; Generali, Daniele.

Front Oncol ; 11: 686776, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-34262869

14.

Quantitative proteomics reveals a "poised quiescence" cellular state after triggering the DNA replication origin activation checkpoint.

Mulvey, Claire; Tudzarova, Slavica; Crawford, Mark; Williams, Gareth H; Stoeber, Kai; Godovac-Zimmermann, Jasminka.

J Proteome Res ; 9(10): 5445-60, 2010 Oct 01.

Artigo em Inglês | MEDLINE | ID: mdl-20707412

15.

Biomarkers in bladder cancer.

Proctor, Ian; Stoeber, Kai; Williams, Gareth H.

Histopathology ; 57(1): 1-13, 2010 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-20579130

16.

Cdc7 kinase is a predictor of survival and a novel therapeutic target in epithelial ovarian carcinoma.

Kulkarni, Anjana A; Kingsbury, Sarah R; Tudzarova, Slavica; Hong, Hye-Kyung; Loddo, Marco; Rashid, Mohammed; Rodriguez-Acebes, Sara; Prevost, Andrew T; Ledermann, Jonathan A; Stoeber, Kai; Williams, Gareth H.

Clin Cancer Res ; 15(7): 2417-25, 2009 Apr 01.

Artigo em Inglês | MEDLINE | ID: mdl-19318489

17.

Interobserver Reliability of Programmed Cell Death Ligand-1 Scoring Using the VENTANA PD-L1 (SP263) Assay in NSCLC.

Williams, Gareth H; Nicholson, Andrew G; Snead, David R J; Thunnissen, Erik; Lantuejoul, Sylvie; Cane, Paul; Kerr, Keith M; Loddo, Marco; Scott, Marietta L J; Scorer, Paul W; Barker, Craig.

J Thorac Oncol ; 15(4): 550-555, 2020 04.

Artigo em Inglês | MEDLINE | ID: mdl-31778799

18.

Identification of an arginine-rich motif in human papillomavirus type 1 E1;E4 protein necessary for E4-mediated inhibition of cellular DNA synthesis in vitro and in cells.

Roberts, Sally; Kingsbury, Sarah R; Stoeber, Kai; Knight, Gillian L; Gallimore, Phillip H; Williams, Gareth H.

J Virol ; 82(18): 9056-64, 2008 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-18632869

19.

Molecular structure of human geminin.

Okorokov, Andrei L; Orlova, Elena V; Kingsbury, Sarah R; Bagneris, Claire; Gohlke, Ulrich; Williams, Gareth H; Stoeber, Kai.

Nat Struct Mol Biol ; 11(10): 1021-2, 2004 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-15378034

20.

Modular assembly using sequential palladium coupling gives easy access to the SMoC class of cellular transporters.

Rebstock, Anne-Sophie; Visintin, Cristina; Leo, Elisabetta; Garcia Posada, Cristina; Kingsbury, Sarah R; Williams, Gareth H; Stoeber, Kai; Selwood, David L.

Chembiochem ; 9(11): 1787-96, 2008 Jul 21.

Artigo em Inglês | MEDLINE | ID: mdl-18604831

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