Detalhe da pesquisa
1.
A new herbicidal site of action: Cinmethylin binds to acyl-ACP thioesterase and inhibits plant fatty acid biosynthesis.
Pestic Biochem Physiol
; 148: 116-125, 2018 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-29891362
2.
Conformational Aspects in the Design of Inhibitors for Serine Hydroxymethyltransferase (SHMT): Biphenyl, Aryl Sulfonamide, and Aryl Sulfone Motifs.
Chemistry
; 23(57): 14345-14357, 2017 Oct 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28967982
3.
Deorphaning pyrrolopyrazines as potent multi-target antimalarial agents.
Angew Chem Int Ed Engl
; 53(27): 7079-84, 2014 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24895172
4.
Pseudilins: halogenated, allosteric inhibitors of the non-mevalonate pathway enzyme IspD.
Angew Chem Int Ed Engl
; 53(8): 2235-9, 2014 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-24446431
5.
Agrochemical Lessons for Infectious Disease Research: New Resistance Breaking Antifungal Hits against Candida auris.
ACS Med Chem Lett
; 14(2): 136-140, 2023 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36793433
6.
Inhibition profile of trifludimoxazin towards PPO2 target site mutations.
Pest Manag Sci
; 79(2): 507-519, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-36178376
7.
Selective killing of the human gastric pathogen Helicobacter pylori by mitochondrial respiratory complex I inhibitors.
Cell Chem Biol
; 30(5): 499-512.e5, 2023 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37100053
8.
Screening of antifungal azole drugs and agrochemicals with an adapted alamarBlue-based assay demonstrates antibacterial activity of croconazole against Mycobacterium ulcerans.
Antimicrob Agents Chemother
; 56(12): 6410-3, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23006761
9.
Targeting the IspD Enzyme in the MEP Pathway: Identification of a Novel Fragment Class.
ChemMedChem
; 17(5): e202100679, 2022 03 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34918860
10.
Inhibition of acyl-ACP thioesterase as site of action of the commercial herbicides cumyluron, oxaziclomefone, bromobutide, methyldymron and tebutam.
Pest Manag Sci
; 78(8): 3620-3629, 2022 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-35604014
11.
Assessment of the rules related to gaining activity against Gram-negative bacteria.
RSC Med Chem
; 12(4): 593-601, 2021 Apr 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34046630
12.
Search for the Active Ingredients from a 2-Aminothiazole DMSO Stock Solution with Antimalarial Activity.
ChemMedChem
; 16(13): 2089-2093, 2021 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33844432
13.
Design, synthesis and herbicidal activity of new iron chelating motifs for HPPD-inhibitors.
Bioorg Med Chem
; 17(12): 4221-9, 2009 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19028100
14.
Potent Inhibitors of Plasmodial Serine Hydroxymethyltransferase (SHMT) Featuring a Spirocyclic Scaffold.
ChemMedChem
; 13(9): 931-943, 2018 05 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29655285
15.
Targeting the Mycobacterium ulcerans cytochrome bc1:aa3 for the treatment of Buruli ulcer.
Nat Commun
; 9(1): 5370, 2018 12 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30560872
16.
Mechanism of Allosteric Inhibition of the Enzyme IspD by Three Different Classes of Ligands.
ACS Chem Biol
; 12(8): 2132-2138, 2017 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28686408
17.
Antimalarial Inhibitors Targeting Serine Hydroxymethyltransferase (SHMT) with in Vivo Efficacy and Analysis of their Binding Mode Based on X-ray Cocrystal Structures.
J Med Chem
; 60(12): 4840-4860, 2017 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-28537728
18.
Inhibitors of the herbicidal target IspD: allosteric site binding.
Angew Chem Int Ed Engl
; 50(34): 7931-5, 2011 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-21766403
19.
An amphiphilic graft copolymer-based nanoparticle platform for reduction-responsive anticancer and antimalarial drug delivery.
Nanoscale
; 8(31): 14858-69, 2016 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-27452350
20.
Aryl Bis-Sulfonamide Inhibitors of IspF from Arabidopsis thaliana and Plasmodium falciparum.
ChemMedChem
; 10(12): 2090-8, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26435072