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1.
Zhongguo Zhong Yao Za Zhi ; 42(1): 94-99, 2017 Jan.
Artigo em Zh | MEDLINE | ID: mdl-28945031

RESUMO

Using four Uncariae Cum Uncis materials including Uncaria sinensis (HGT), U. hirsutea (MGT), Jianhe U. rhynchophylla (JHGT) and U. rhynchophylla(GT) as the research objects, the correlations between medicinal materials' yield and photosynthetic ecophysiology-factors in the plant exuberant growth period were studied. Results showed that the Uncaria plants net photosynthetic rate (Pn) changed by unimodal curve. There was not "midday depression" phenomenon. There was a different relationship among the photosynthetic ecophysiology-factors and between photosynthetic ecophysiology-factors and medicinal materials' yield. Pn,Tl,Gs had a significant correlation with medicinal materials' yield(M)and were the most important factors of growth.


Assuntos
Fotossíntese , Uncaria/fisiologia , Folhas de Planta/fisiologia , Plantas Medicinais/química , Plantas Medicinais/fisiologia , Uncaria/química
2.
Phytochemistry ; 162: 216-223, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-30953908

RESUMO

Ten previously undescribed bibenzyl derivatives (bletistrins A-J), including 5 that have hydroxyl-substituted chiral centres on the aliphatic bibenzyl bridge, along with twelve known bibenzyl derivatives, were isolated from the rhizomes of Bletilla striata. The structures of bletistrins A-J were primarily elucidated on the basis of their 1D and 2D NMR spectroscopic data. The absolute configurations of bletistrins A, D, F, H and I were determined by electronic circular dichroism (ECD) spectroscopic analysis and optical rotation value. Most of the isolated compounds were evaluated for their antibacterial activities against 3 g-positive bacterial strains and 1 g-negative bacterial strain. Bletistrins F, G, and J, bulbocol, shanciguol and shancigusin B showed inhibitory activities, with MICs of (3-28 µg/mL) against S. aureus ATCC 6538.


Assuntos
Antibacterianos/química , Antibacterianos/farmacologia , Bibenzilas/química , Bibenzilas/farmacologia , Orchidaceae/química , Tubérculos/química , Testes de Sensibilidade Microbiana , Modelos Moleculares , Conformação Molecular , Staphylococcus aureus/efeitos dos fármacos
3.
Fitoterapia ; 138: 104350, 2019 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-31473333

RESUMO

Three new bibenzyl derivatives (bletstrins A-C, 1-3), including two bibenzyls that have hydroxyl-substituted chiral centers on the aliphatic bibenzyl bridge, along with eighteen known stilbenoids (4-21) were isolated from the tubers of Bletilla striata. The structures of new compounds were elucidated by the use of 1D/2D NMR spectroscopic data. The absolute configurations of bletitrins A and B were determined by optical rotation value. Compounds 13-16 were isolated from the Orchidaceae for the first time. Most of the isolated compounds were evaluated for their antibacterial activities against three gram-positive bacterial strains and one gram-negative bacterial strain. Compounds 4, 10, 12, 14, 15, 16 and 18 showed potent inhibitory activities, with MICs of (6-52 µg/mL) against S. aureus ATCC 6538.


Assuntos
Antibacterianos/farmacologia , Orchidaceae/química , Tubérculos/química , Estilbenos/farmacologia , Antibacterianos/isolamento & purificação , Bibenzilas/isolamento & purificação , Bibenzilas/farmacologia , China , Testes de Sensibilidade Microbiana , Estrutura Molecular , Compostos Fitoquímicos/isolamento & purificação , Compostos Fitoquímicos/farmacologia , Staphylococcus aureus/efeitos dos fármacos , Estilbenos/isolamento & purificação
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