Pesquisa | BVS Violência e Saúde

1.

The primordial differentiation of tumor-specific memory CD8⁺ T cells as bona fide responders to PD-1/PD-L1 blockade in draining lymph nodes.

Huang, Qizhao; Wu, Xia; Wang, Zhiming; Chen, Xiangyu; Wang, Lisha; Lu, Yijun; Xiong, Dan; Liu, Qiao; Tian, Yuhan; Lin, Huayu; Guo, Junyi; Wen, Shuqiong; Dong, Wei; Yang, Xiaofan; Yuan, Yuchen; Yue, Zhengliang; Lei, Shun; Wu, Qing; Ran, Ling; Xie, Luoyingzi; Wang, Yifei; Gao, Leiqiong; Tian, Qin; Zhou, Xinyuan; Sun, Beicheng; Xu, Lifan; Tang, Zhonghui; Ye, Lilin.

Cell ; 185(22): 4049-4066.e25, 2022 10 27.

Artigo em Inglês | MEDLINE | ID: mdl-36208623

2.

The kinase complex mTORC2 promotes the longevity of virus-specific memory CD4⁺ T cells by preventing ferroptosis.

Wang, Yifei; Tian, Qin; Hao, Yaxing; Yao, Wei; Lu, Jinjin; Chen, Cheng; Chen, Xiangyu; Lin, Yao; Huang, Qizhao; Xu, Lifan; Hu, Jianjun; Lei, Shun; Wei, Zhengping; Luo, Yuan; Li, Zhirong; Hu, Li; Tang, Jianfang; Wu, Qing; Zhou, Xinyuan; Wu, Yuzhang; Yin, Zhinan; Xu, Jianqing; Ye, Lilin.

Nat Immunol ; 23(2): 303-317, 2022 02.

Artigo em Inglês | MEDLINE | ID: mdl-34949833

3.

The transcription factor TCF-1 initiates the differentiation of T(FH) cells during acute viral infection.

Xu, Lifan; Cao, Yi; Xie, Zhunyi; Huang, Qizhao; Bai, Qiang; Yang, Xia; He, Ran; Hao, Yaxing; Wang, Haoqiang; Zhao, Tingting; Fan, Zhonglei; Qin, Aijian; Ye, Jianqiang; Zhou, Xinyuan; Ye, Lilin; Wu, Yuzhang.

Nat Immunol ; 16(9): 991-9, 2015 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-26214740

4.

The Kinase mTORC1 Promotes the Generation and Suppressive Function of Follicular Regulatory T Cells.

Xu, Lifan; Huang, Qizhao; Wang, Haoqiang; Hao, Yaxing; Bai, Qiang; Hu, Jianjun; Li, Yiding; Wang, Pengcheng; Chen, Xiangyu; He, Ran; Li, Bingshou; Yang, Xia; Zhao, Tingting; Zhang, Yanyan; Wang, Yifei; Ou, Juanjuan; Liang, Houjie; Wu, Yuzhang; Zhou, Xinyuan; Ye, Lilin.

Immunity ; 47(3): 538-551.e5, 2017 09 19.

Artigo em Inglês | MEDLINE | ID: mdl-28930662

5.

Nasal Spray of Neutralizing Monoclonal Antibody 35B5 Confers Potential Prophylaxis Against Severe Acute Respiratory Syndrome Coronavirus 2 Variants of Concern: A Small-Scale Clinical Trial.

Lin, Yao; Yue, Shuai; Yang, Yang; Yang, Sen; Pan, Zhiwei; Yang, Xiaofan; Gao, Leiqiong; Zhou, Jing; Li, Zhirong; Hu, Li; Tang, Jianfang; Wu, Qing; Lei, Shun; Tian, Qin; Wang, Yifei; Hao, Yaxing; Xu, Lifan; Huang, Qizhao; Zhu, Bo; Chen, Yaokai; Chen, Xiangyu; Ye, Lilin.

Clin Infect Dis ; 76(3): e336-e341, 2023 02 08.

Artigo em Inglês | MEDLINE | ID: mdl-35666466

6.

Follicular CXCR5- expressing CD8(+) T cells curtail chronic viral infection.

He, Ran; Hou, Shiyue; Liu, Cheng; Zhang, Anli; Bai, Qiang; Han, Miao; Yang, Yu; Wei, Gang; Shen, Ting; Yang, Xinxin; Xu, Lifan; Chen, Xiangyu; Hao, Yaxing; Wang, Pengcheng; Zhu, Chuhong; Ou, Juanjuan; Liang, Houjie; Ni, Ting; Zhang, Xiaoyan; Zhou, Xinyuan; Deng, Kai; Chen, Yaokai; Luo, Yadong; Xu, Jianqing; Qi, Hai; Wu, Yuzhang; Ye, Lilin.

Nature ; 537(7620): 412-428, 2016 08 02.

Artigo em Inglês | MEDLINE | ID: mdl-27501245

7.

mTOR Promotes Antiviral Humoral Immunity by Differentially Regulating CD4 Helper T Cell and B Cell Responses.

Ye, Lilin; Lee, Junghwa; Xu, Lifan; Mohammed, Ata-Ur-Rasheed; Li, Weiyan; Hale, J Scott; Tan, Wendy G; Wu, Tuoqi; Davis, Carl W; Ahmed, Rafi; Araki, Koichi.

J Virol ; 91(4)2017 02 15.

Artigo em Inglês | MEDLINE | ID: mdl-27974559

8.

Mammalian target of rapamycin complex 1 signalling is essential for germinal centre reaction.

Li, Bingshou; Li, Zhirong; Wang, Pengcheng; Huang, Qizhao; Xu, Lifan; He, Ran; Ye, Lilin; Bai, Qiang.

Immunology ; 152(2): 276-286, 2017 10.

Artigo em Inglês | MEDLINE | ID: mdl-28557002

9.

Erratum: Follicular CXCR5-expressing CD8+ T cells curtail chronic viral infection.

He, Ran; Hou, Shiyue; Liu, Cheng; Zhang, Anli; Bai, Qiang; Han, Miao; Yang, Yu; Wei, Gang; Shen, Ting; Yang, Xinxin; Xu, Lifan; Chen, Xiangyu; Hao, Yaxing; Wang, Pengcheng; Zhu, Chuhong; Ou, Juanjuan; Liang, Houjie; Ni, Ting; Zhang, Xiaoyan; Zhou, Xinyuan; Deng, Kai; Chen, Yaokai; Luo, Yadong; Xu, Jianqing; Qi, Hai; Wu, Yuzhang; Ye, Lilin.

Nature ; 540(7633): 470, 2016 10 19.

Artigo em Inglês | MEDLINE | ID: mdl-27762350

10.

Draining Lymph Node Metastasis Model for Assessing the Dynamics of Antigen-Specific CD8+ T Cells During Tumorigenesis.

Zhang, Yan; Su, Xingxing; Wang, Lisha; Yue, Zhengliang; Liu, Qiao; Ran, Ling; Lei, Shun; Hu, Jianjun; Xu, Lifan; Ye, Lilin; Ji, Ping; Li, Guimei; Huang, Qizhao; Wen, Shuqiong.

J Vis Exp ; (203)2024 Jan 26.

Artigo em Inglês | MEDLINE | ID: mdl-38345257

11.

An oncolytic virus delivering tumor-irrelevant bystander T cell epitopes induces anti-tumor immunity and potentiates cancer immunotherapy.

Chen, Xiangyu; Zhao, Jing; Yue, Shuai; Li, Ziyu; Duan, Xiang; Lin, Yao; Yang, Yang; He, Junjian; Gao, Leiqiong; Pan, Zhiwei; Yang, Xiaofan; Su, Xingxing; Huang, Min; Li, Xiao; Zhao, Ye; Zhang, Xuehui; Li, Zhirong; Hu, Li; Tang, Jianfang; Hao, Yaxing; Tian, Qin; Wang, Yifei; Xu, Lifan; Huang, Qizhao; Cao, Yingjiao; Chen, Yaokai; Zhu, Bo; Li, Yan; Bai, Fan; Zhang, Guozhong; Ye, Lilin.

Nat Cancer ; 2024 Apr 12.

Artigo em Inglês | MEDLINE | ID: mdl-38609488

12.

[Epigenetics in cancer stem cells].

Xu, Li-Fan; Zhang, Ji; Tian, Zhi-Qiang; Wu, Yu-Zhang.

Yi Chuan ; 35(9): 1049-57, 2013 Sep.

Artigo em Zh | MEDLINE | ID: mdl-24400477

13.

PD-1/PD-L1 blockade restores tumor-induced COVID-19 vaccine bluntness.

Chen, Xiangyu; Lin, Yao; Yue, Shuai; Yang, Yang; Yang, Xiaofan; He, Junjian; Gao, Leiqiong; Li, Zhirong; Hu, Li; Tang, Jianfang; Wang, Yifei; Tian, Qin; Hao, Yaxing; Xu, Lifan; Huang, Qizhao; Cao, Yingjiao; Ye, Lilin.

Vaccine ; 41(34): 4986-4995, 2023 07 31.

Artigo em Inglês | MEDLINE | ID: mdl-37400286

14.

A novel strategy to investigate the factors regulating the Treg to Tfr transition during acute viral infection.

Lin, Huayu; Wang, Haoqiang; Liu, Qiao; Wang, Zhiming; Wen, Shuqiong; Wang, Lisha; Guo, Junyi; Ran, Ling; Yue, Zhengliang; Wu, Qing; Tang, Jianfang; Li, Zhirong; Hu, Li; Xu, Lifan; Huang, Qizhao; Ye, Lilin.

J Immunol Methods ; 505: 113266, 2022 06.

Artigo em Inglês | MEDLINE | ID: mdl-35398062

15.

Tumor-Specific CD4⁺ T Cells Restrain Established Metastatic Melanoma by Developing Into Cytotoxic CD4^- T Cells.

Liu, Qiao; Wang, Lisha; Lin, Huayu; Wang, Zhiming; Wu, Jialin; Guo, Junyi; Wen, Shuqiong; Ran, Ling; Yue, Zhengliang; Su, Xingxing; Wu, Qing; Tang, Jianfang; Li, Zhirong; Hu, Li; Xu, Lifan; Ye, Lilin; Huang, Qizhao.

Front Immunol ; 13: 875718, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-35784297

16.

Differential expression of inhibitory receptor NKG2A distinguishes disease-specific exhausted CD8⁺ T cells.

Chen, Xiangyu; Lin, Yao; Yue, Shuai; Yang, Yang; Wang, Xinxin; Pan, Zhiwei; Yang, Xiaofan; Gao, Leiqiong; Zhou, Jing; Li, Zhirong; Hu, Li; Tang, Jianfang; Wu, Qing; Wang, Yifei; Tian, Qin; Hao, Yaxing; Xu, Lifan; Zhu, Bo; Huang, Qizhao; Ye, Lilin.

MedComm (2020) ; 3(1): e111, 2022 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-35281793

17.

A potent human monoclonal antibody with pan-neutralizing activities directly dislocates S trimer of SARS-CoV-2 through binding both up and down forms of RBD.

Wang, Xiaofei; Hu, Ao; Chen, Xiangyu; Zhang, Yixin; Yu, Fei; Yue, Shuai; Li, Arong; Zhang, Junsong; Pan, Zhiwei; Yang, Yang; Lin, Yao; Gao, Leiqiong; Zhou, Jing; Zhao, Jing; Li, Fang; Shi, Yaling; Huang, Feng; Yang, Xiaofan; Peng, Yi; Tu, Luoyang; Zhang, Huan; Zheng, Huanying; He, Jun; Zhang, Hui; Xu, Lifan; Huang, Qizhao; Zhu, Yongqun; Deng, Kai; Ye, Lilin.

Signal Transduct Target Ther ; 7(1): 114, 2022 04 05.

Artigo em Inglês | MEDLINE | ID: mdl-35383141

18.

CD4⁺ T-cell epitope-based heterologous prime-boost vaccination potentiates anti-tumor immunity and PD-1/PD-L1 immunotherapy.

Xiao, Minglu; Xie, Luoyingzi; Cao, Guoshuai; Lei, Shun; Wang, Pengcheng; Wei, Zhengping; Luo, Yuan; Fang, Jingyi; Yang, Xingxing; Huang, Qizhao; Xu, Lifan; Guo, Junyi; Wen, Shuqiong; Wang, Zhiming; Wu, Qing; Tang, Jianfang; Wang, Lisha; Chen, Xiangyu; Chen, Cheng; Zhang, Yanyan; Yao, Wei; Ye, Jianqiang; He, Ran; Huang, Jun; Ye, Lilin.

J Immunother Cancer ; 10(5)2022 05.

Artigo em Inglês | MEDLINE | ID: mdl-35580929

19.

Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice.

Wang, Lisha; Wang, Zhiming; Guo, Junyi; Lin, Huayu; Wen, Shuqiong; Liu, Qiao; Li, Yiding; Wu, Qing; Gao, Leiqiong; Chen, Xiangyu; Xie, Luoyingzi; Tian, Qin; Tang, Jianfang; Li, Zhirong; Hu, Li; Wang, Juan; Xu, Lifan; Huang, Qizhao; Ye, Lilin.

J Vis Exp ; (172)2021 06 12.

Artigo em Inglês | MEDLINE | ID: mdl-34180896

20.

METTL3-dependent m⁶A modification programs T follicular helper cell differentiation.

Yao, Yingpeng; Yang, Ying; Guo, Wenhui; Xu, Lifan; You, Menghao; Zhang, Yi-Chang; Sun, Zhen; Cui, Xiao; Yu, Guotao; Qi, Zhihong; Liu, Jingjing; Wang, Fang; Liu, Juanjuan; Zhao, Tianyan; Ye, Lilin; Yang, Yun-Gui; Yu, Shuyang.

Nat Commun ; 12(1): 1333, 2021 02 26.

Artigo em Inglês | MEDLINE | ID: mdl-33637761

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