Pesquisa | BVS Violência e Saúde

1.

Atlas Drugged.

Chen, Jung-Kuei; Yaffe, Michael B.

Cell ; 177(4): 803-805, 2019 05 02.

Artigo em Inglês | MEDLINE | ID: mdl-31051104

2.

The intrinsic substrate specificity of the human tyrosine kinome.

Yaron-Barir, Tomer M; Joughin, Brian A; Huntsman, Emily M; Kerelsky, Alexander; Cizin, Daniel M; Cohen, Benjamin M; Regev, Amit; Song, Junho; Vasan, Neil; Lin, Ting-Yu; Orozco, Jose M; Schoenherr, Christina; Sagum, Cari; Bedford, Mark T; Wynn, R Max; Tso, Shih-Chia; Chuang, David T; Li, Lei; Li, Shawn S-C; Creixell, Pau; Krismer, Konstantin; Takegami, Mina; Lee, Harin; Zhang, Bin; Lu, Jingyi; Cossentino, Ian; Landry, Sean D; Uduman, Mohamed; Blenis, John; Elemento, Olivier; Frame, Margaret C; Hornbeck, Peter V; Cantley, Lewis C; Turk, Benjamin E; Yaffe, Michael B; Johnson, Jared L.

Nature ; 629(8014): 1174-1181, 2024 May.

Artigo em Inglês | MEDLINE | ID: mdl-38720073

3.

Dihydropyrimidine accumulation is required for the epithelial-mesenchymal transition.

Shaul, Yoav D; Freinkman, Elizaveta; Comb, William C; Cantor, Jason R; Tam, Wai Leong; Thiru, Prathapan; Kim, Dohoon; Kanarek, Naama; Pacold, Michael E; Chen, Walter W; Bierie, Brian; Possemato, Richard; Reinhardt, Ferenc; Weinberg, Robert A; Yaffe, Michael B; Sabatini, David M.

Cell ; 158(5): 1094-1109, 2014 Aug 28.

Artigo em Inglês | MEDLINE | ID: mdl-25171410

4.

An atlas of substrate specificities for the human serine/threonine kinome.

Johnson, Jared L; Yaron, Tomer M; Huntsman, Emily M; Kerelsky, Alexander; Song, Junho; Regev, Amit; Lin, Ting-Yu; Liberatore, Katarina; Cizin, Daniel M; Cohen, Benjamin M; Vasan, Neil; Ma, Yilun; Krismer, Konstantin; Robles, Jaylissa Torres; van de Kooij, Bert; van Vlimmeren, Anne E; Andrée-Busch, Nicole; Käufer, Norbert F; Dorovkov, Maxim V; Ryazanov, Alexey G; Takagi, Yuichiro; Kastenhuber, Edward R; Goncalves, Marcus D; Hopkins, Benjamin D; Elemento, Olivier; Taatjes, Dylan J; Maucuer, Alexandre; Yamashita, Akio; Degterev, Alexei; Uduman, Mohamed; Lu, Jingyi; Landry, Sean D; Zhang, Bin; Cossentino, Ian; Linding, Rune; Blenis, John; Hornbeck, Peter V; Turk, Benjamin E; Yaffe, Michael B; Cantley, Lewis C.

Nature ; 613(7945): 759-766, 2023 01.

Artigo em Inglês | MEDLINE | ID: mdl-36631611

5.

Sequential application of anticancer drugs enhances cell death by rewiring apoptotic signaling networks.

Lee, Michael J; Ye, Albert S; Gardino, Alexandra K; Heijink, Anne Margriet; Sorger, Peter K; MacBeath, Gavin; Yaffe, Michael B.

Cell ; 149(4): 780-94, 2012 May 11.

Artigo em Inglês | MEDLINE | ID: mdl-22579283

6.

Neutrophil interactions with T cells, platelets, endothelial cells, and of course tumor cells.

Segal, Brahm H; Giridharan, Thejaswini; Suzuki, Sora; Khan, Anm Nazmul H; Zsiros, Emese; Emmons, Tiffany R; Yaffe, Michael B; Gankema, Angela A F; Hoogeboom, Mark; Goetschalckx, Ines; Matlung, Hanke L; Kuijpers, Taco W.

Immunol Rev ; 314(1): 13-35, 2023 03.

Artigo em Inglês | MEDLINE | ID: mdl-36527200

7.

The mission to ensure continued funding for excellent basic research.

Lamond, Angus I; Dikic, Ivan; Nussenzweig, Andre; Müller, Christoph W; Thornton, Janet M; Yaffe, Michael B.

EMBO Rep ; 24(7): e57498, 2023 Jul 05.

Artigo em Inglês | MEDLINE | ID: mdl-37227159

8.

Phospho-Ser/Thr-binding domains: navigating the cell cycle and DNA damage response.

Reinhardt, H Christian; Yaffe, Michael B.

Nat Rev Mol Cell Biol ; 14(9): 563-80, 2013 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-23969844

9.

Cytokine-induced signaling networks prioritize dynamic range over signal strength.

Janes, Kevin A; Reinhardt, H Christian; Yaffe, Michael B.

Cell ; 135(2): 343-54, 2008 Oct 17.

Artigo em Inglês | MEDLINE | ID: mdl-18957207

10.

Pyruvate kinase isoform expression alters nucleotide synthesis to impact cell proliferation.

Lunt, Sophia Y; Muralidhar, Vinayak; Hosios, Aaron M; Israelsen, William J; Gui, Dan Y; Newhouse, Lauren; Ogrodzinski, Martin; Hecht, Vivian; Xu, Kali; Acevedo, Paula N Marín; Hollern, Daniel P; Bellinger, Gary; Dayton, Talya L; Christen, Stefan; Elia, Ilaria; Dinh, Anh T; Stephanopoulos, Gregory; Manalis, Scott R; Yaffe, Michael B; Andrechek, Eran R; Fendt, Sarah-Maria; Vander Heiden, Matthew G.

Mol Cell ; 57(1): 95-107, 2015 Jan 08.

Artigo em Inglês | MEDLINE | ID: mdl-25482511

11.

Comprehensive profiling of the STE20 kinase family defines features essential for selective substrate targeting and signaling output.

Miller, Chad J; Lou, Hua Jane; Simpson, Craig; van de Kooij, Bert; Ha, Byung Hak; Fisher, Oriana S; Pirman, Natasha L; Boggon, Titus J; Rinehart, Jesse; Yaffe, Michael B; Linding, Rune; Turk, Benjamin E.

PLoS Biol ; 17(3): e2006540, 2019 03.

Artigo em Inglês | MEDLINE | ID: mdl-30897078

12.

Design and synthesis of a new orthogonally protected glutamic acid analog and its use in the preparation of high affinity polo-like kinase 1 polo-box domain - binding peptide macrocycles.

Hymel, David; Tsuji, Kohei; Grant, Robert A; Chingle, Ramesh M; Kunciw, Dominique L; Yaffe, Michael B; Burke, Terrence R.

Org Biomol Chem ; 19(36): 7843-7854, 2021 09 22.

Artigo em Inglês | MEDLINE | ID: mdl-34346472

13.

MK2 contributes to tumor progression by promoting M2 macrophage polarization and tumor angiogenesis.

Suarez-Lopez, Lucia; Sriram, Ganapathy; Kong, Yi Wen; Morandell, Sandra; Merrick, Karl A; Hernandez, Yuliana; Haigis, Kevin M; Yaffe, Michael B.

Proc Natl Acad Sci U S A ; 115(18): E4236-E4244, 2018 05 01.

Artigo em Inglês | MEDLINE | ID: mdl-29666270

14.

Multiplexed Plasma Immune Mediator Signatures Can Differentiate Sepsis From NonInfective SIRS: American Surgical Association 2020 Annual Meeting Paper.

Cahill, Laura A; Joughin, Brian A; Kwon, Woon Yong; Itagaki, Kiyoshi; Kirk, Charlotte H; Shapiro, Nathan I; Otterbein, Leo E; Yaffe, Michael B; Lederer, James A; Hauser, Carl J.

Ann Surg ; 272(4): 604-610, 2020 10.

Artigo em Inglês | MEDLINE | ID: mdl-32932316

15.

Formyl Peptide Receptor-1 Blockade Prevents Receptor Regulation by Mitochondrial Danger-Associated Molecular Patterns and Preserves Neutrophil Function After Trauma.

Itagaki, Kiyoshi; Kaczmarek, Elzbieta; Kwon, Woon Yong; Chen, Li; Vlková, Barbora; Zhang, Quanzhi; Riça, Ingred; Yaffe, Michael B; Campbell, Yan; Marusich, Michael F; Wang, Ji Ming; Gong, Wang-Hua; Gao, Ji-Liang; Jung, Françoise; Douglas, Garry; Otterbein, Leo E; Hauser, Carl J.

Crit Care Med ; 48(2): e123-e132, 2020 02.

Artigo em Inglês | MEDLINE | ID: mdl-31939811

16.

Influence of Tranexamic Acid on Inflammatory Signaling in Trauma.

Barrett, Christopher D; Kong, Yi Wen; Yaffe, Michael B.

Semin Thromb Hemost ; 46(2): 183-188, 2020 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-32160643

17.

Development of Rapid Response Capabilities in a Large COVID-19 Alternate Care Site Using Failure Modes and Effect Analysis with In Situ Simulation.

Levy, Nadav; Zucco, Liana; Ehrlichman, Richard J; Hirschberg, Ronald E; Hutton Johnson, Stacy; Yaffe, Michael B; Ramachandran, Satya Krishna; Bose, Somnath; Leibowitz, Akiva.

Anesthesiology ; 133(5): 985-996, 2020 11 01.

Artigo em Inglês | MEDLINE | ID: mdl-32773686

18.

Fixin' to divide.

Mohammad, Duaa H; Yaffe, Michael B.

Mol Cell ; 45(3): 273-5, 2012 Feb 10.

Artigo em Inglês | MEDLINE | ID: mdl-22325348

19.

Cytokine Storm.

Gaestel, Matthias; Nebreda, Angel R; Yaffe, Michael B.

N Engl J Med ; 384(16): e59, 2021 Apr 22.

Artigo em Inglês | MEDLINE | ID: mdl-33882214

20.

The bromodomain protein Brd4 insulates chromatin from DNA damage signalling.

Floyd, Scott R; Pacold, Michael E; Huang, Qiuying; Clarke, Scott M; Lam, Fred C; Cannell, Ian G; Bryson, Bryan D; Rameseder, Jonathan; Lee, Michael J; Blake, Emily J; Fydrych, Anna; Ho, Richard; Greenberger, Benjamin A; Chen, Grace C; Maffa, Amanda; Del Rosario, Amanda M; Root, David E; Carpenter, Anne E; Hahn, William C; Sabatini, David M; Chen, Clark C; White, Forest M; Bradner, James E; Yaffe, Michael B.

Nature ; 498(7453): 246-50, 2013 Jun 13.

Artigo em Inglês | MEDLINE | ID: mdl-23728299

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