Pesquisa | BVS Violência e Saúde

1.

Enhanced prime editing systems by manipulating cellular determinants of editing outcomes.

Chen, Peter J; Hussmann, Jeffrey A; Yan, Jun; Knipping, Friederike; Ravisankar, Purnima; Chen, Pin-Fang; Chen, Cidi; Nelson, James W; Newby, Gregory A; Sahin, Mustafa; Osborn, Mark J; Weissman, Jonathan S; Adamson, Britt; Liu, David R.

Cell ; 184(22): 5635-5652.e29, 2021 10 28.

Artigo em Inglês | MEDLINE | ID: mdl-34653350

2.

Mapping the genetic landscape of DNA double-strand break repair.

Hussmann, Jeffrey A; Ling, Jia; Ravisankar, Purnima; Yan, Jun; Cirincione, Ann; Xu, Albert; Simpson, Danny; Yang, Dian; Bothmer, Anne; Cotta-Ramusino, Cecilia; Weissman, Jonathan S; Adamson, Britt.

Cell ; 184(22): 5653-5669.e25, 2021 10 28.

Artigo em Inglês | MEDLINE | ID: mdl-34672952

3.

Inducing trained immunity in pro-metastatic macrophages to control tumor metastasis.

Ding, Chuanlin; Shrestha, Rejeena; Zhu, Xiaojuan; Geller, Anne E; Wu, Shouzhen; Woeste, Matthew R; Li, Wenqian; Wang, Haomin; Yuan, Fang; Xu, Raobo; Chariker, Julia H; Hu, Xiaoling; Li, Hong; Tieri, David; Zhang, Huang-Ge; Rouchka, Eric C; Mitchell, Robert; Siskind, Leah J; Zhang, Xiang; Xu, Xiaoji G; McMasters, Kelly M; Yu, Yan; Yan, Jun.

Nat Immunol ; 24(2): 239-254, 2023 02.

Artigo em Inglês | MEDLINE | ID: mdl-36604547

4.

Publisher Correction: SERPINB1-mediated checkpoint of inflammatory caspase activation.

Choi, Youn Jung; Kim, Stephanie; Choi, Younho; Nielsen, Travis B; Yan, Jun; Lu, Alvin; Ruan, Jianbin; Lee, Hye-Ra; Wu, Hao; Spellberg, Brad; Jung, Jae U.

Nat Immunol ; 20(5): 664, 2019 May.

Artigo em Inglês | MEDLINE | ID: mdl-30846880

5.

SERPINB1-mediated checkpoint of inflammatory caspase activation.

Choi, Youn Jung; Kim, Stephanie; Choi, Younho; Nielsen, Travis B; Yan, Jun; Lu, Alvin; Ruan, Jianbin; Lee, Hye-Ra; Wu, Hao; Spellberg, Brad; Jung, Jae U.

Nat Immunol ; 20(3): 276-287, 2019 03.

Artigo em Inglês | MEDLINE | ID: mdl-30692621

6.

The chemokine CCL1 triggers an AMFR-SPRY1 pathway that promotes differentiation of lung fibroblasts into myofibroblasts and drives pulmonary fibrosis.

Liu, Shan-Shan; Liu, Chang; Lv, Xiao-Xi; Cui, Bing; Yan, Jun; Li, Yun-Xuan; Li, Ke; Hua, Fang; Zhang, Xiao-Wei; Yu, Jiao-Jiao; Yu, Jin-Mei; Wang, Feng; Shang, Shuang; Li, Ping-Ping; Zhou, Zhi-Guang; Xiao, Yang; Hu, Zhuo-Wei.

Immunity ; 54(9): 2042-2056.e8, 2021 09 14.

Artigo em Inglês | MEDLINE | ID: mdl-34407391

7.

Confinement and low adhesion induce fast amoeboid migration of slow mesenchymal cells.

Liu, Yan-Jun; Le Berre, Maël; Lautenschlaeger, Franziska; Maiuri, Paolo; Callan-Jones, Andrew; Heuzé, Mélina; Takaki, Tohru; Voituriez, Raphaël; Piel, Matthieu.

Cell ; 160(4): 659-672, 2015 Feb 12.

Artigo em Inglês | MEDLINE | ID: mdl-25679760

8.

Improving prime editing with an endogenous small RNA-binding protein.

Yan, Jun; Oyler-Castrillo, Paul; Ravisankar, Purnima; Ward, Carl C; Levesque, Sébastien; Jing, Yangwode; Simpson, Danny; Zhao, Anqi; Li, Hui; Yan, Weihao; Goudy, Laine; Schmidt, Ralf; Solley, Sabrina C; Gilbert, Luke A; Chan, Michelle M; Bauer, Daniel E; Marson, Alexander; Parsons, Lance R; Adamson, Britt.

Nature ; 628(8008): 639-647, 2024 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-38570691

9.

R-loop-dependent promoter-proximal termination ensures genome stability.

Xu, Congling; Li, Chengyu; Chen, Jiwei; Xiong, Yan; Qiao, Zhibin; Fan, Pengyu; Li, Conghui; Ma, Shuangyu; Liu, Jin; Song, Aixia; Tao, Bolin; Xu, Tao; Xu, Wei; Chi, Yayun; Xue, Jingyan; Wang, Pu; Ye, Dan; Gu, Hongzhou; Zhang, Peng; Wang, Qiong; Xiao, Ruijing; Cheng, Jingdong; Zheng, Hai; Yu, Xiaoli; Zhang, Zhen; Wu, Jiong; Liang, Kaiwei; Liu, Yan-Jun; Lu, Huasong; Chen, Fei Xavier.

Nature ; 621(7979): 610-619, 2023 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-37557913

10.

Antitumor Î³Î´ T cells need oxygen to function.

Yan, Jun.

Nat Immunol ; 22(3): 268-269, 2021 03.

Artigo em Inglês | MEDLINE | ID: mdl-33574620

11.

Axial Higgs mode detected by quantum pathway interference in RTe₃.

Wang, Yiping; Petrides, Ioannis; McNamara, Grant; Hosen, Md Mofazzel; Lei, Shiming; Wu, Yueh-Chun; Hart, James L; Lv, Hongyan; Yan, Jun; Xiao, Di; Cha, Judy J; Narang, Prineha; Schoop, Leslie M; Burch, Kenneth S.

Nature ; 606(7916): 896-901, 2022 06.

Artigo em Inglês | MEDLINE | ID: mdl-35676485

12.

Prime Editing: Precision Genome Editing by Reverse Transcription.

Yan, Jun; Cirincione, Ann; Adamson, Britt.

Mol Cell ; 77(2): 210-212, 2020 01 16.

Artigo em Inglês | MEDLINE | ID: mdl-31951546

13.

Coding region polyadenylation generates a truncated tRNA synthetase that counters translation repression.

Yao, Peng; Potdar, Alka A; Arif, Abul; Ray, Partho Sarothi; Mukhopadhyay, Rupak; Willard, Belinda; Xu, Yichi; Yan, Jun; Saidel, Gerald M; Fox, Paul L.

Cell ; 149(1): 88-100, 2012 Mar 30.

Artigo em Inglês | MEDLINE | ID: mdl-22386318

14.

DNA nanomachines reveal an adaptive energy mode in confinement-induced amoeboid migration powered by polarized mitochondrial distribution.

Liu, Yixin; Wang, Ya-Jun; Du, Yang; Liu, Wei; Huang, Xuedong; Fan, Zihui; Lu, Jiayin; Yi, Runqiu; Xiang, Xiao-Wei; Xia, Xinwei; Gu, Hongzhou; Liu, Yan-Jun; Liu, Baohong.

Proc Natl Acad Sci U S A ; 121(14): e2317492121, 2024 Apr 02.

Artigo em Inglês | MEDLINE | ID: mdl-38547056

15.

The miR165/166-PHABULOSA module promotes thermotolerance by transcriptionally and posttranslationally regulating HSFA1.

Li, Jie; Cao, Yiming; Zhang, Jiaxin; Zhu, Cuijing; Tang, Guiliang; Yan, Jun.

Plant Cell ; 35(8): 2952-2971, 2023 08 02.

Artigo em Inglês | MEDLINE | ID: mdl-37132478

16.

Myosin 9 and N-glycans jointly regulate human papillomavirus entry.

Zhang, Yang; Liu, Wei; He, Fujie; Liu, Yan-Jun; Jiang, Hao; Hao, Cui; Wang, Wei.

J Biol Chem ; 300(2): 105660, 2024 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-38242322

17.

A plasma membrane-localized transporter remobilizes aleurone layer magnesium for seed germination in rice.

Guan, Liurong; Yin, Li; Liu, Yingna; Yan, Jun; Wang, Bin; Luan, Mingda; Lan, Wenzhi.

Plant J ; 2024 Jun 04.

Artigo em Inglês | MEDLINE | ID: mdl-38837713

18.

A nanopore-based cucumber genome assembly reveals structural variations at two QTLs controlling hypocotyl elongation.

Liu, Bin; Shen, Cheng-Cheng; Xia, Shi-Wei; Song, Shan-Shan; Su, Li-Hong; Li, Yu; Hao, Qian; Liu, Yan-Jun; Guan, Dai-Lu; Wang, Ning; Wang, Wen-Jiao; Zhao, Xiang; Li, Huan-Xiu; Li, Xi-Xiang; Lai, Yun-Song.

Plant Physiol ; 195(2): 970-985, 2024 May 31.

Artigo em Inglês | MEDLINE | ID: mdl-38478469

19.

The chemokine CCL1 triggers an AMFR-SPRY1 pathway that promotes differentiation of lung fibroblasts into myofibroblasts and drives pulmonary fibrosis.

Liu, Shan-Shan; Liu, Chang; Lv, Xiao-Xi; Cui, Bing; Yan, Jun; Li, Yun-Xuan; Li, Ke; Hua, Fang; Zhang, Xiao-Wei; Yu, Jiao-Jiao; Yu, Jin-Mei; Wang, Feng; Shang, Shuang; Li, Ping-Ping; Zhou, Zhi-Guang; Xiao, Yang; Hu, Zhuo-Wei.

Immunity ; 54(10): 2433-2435, 2021 Oct 12.

Artigo em Inglês | MEDLINE | ID: mdl-34644559

20.

PDIA3 orchestrates effector T cell program by serving as a chaperone to facilitate the non-canonical nuclear import of STAT1 and PKM2.

Yang, Chun-Liang; Wang, Fa-Xi; Luo, Jia-Hui; Rong, Shan-Jie; Lu, Wan-Ying; Chen, Qi-Jie; Xiao, Jun; Wang, Ting; Song, Dan-Ni; Liu, Jing; Mo, Qian; Li, Shuo; Chen, Yu; Wang, Ya-Nan; Liu, Yan-Jun; Yan, Tong; Gu, Wei-Kuan; Zhang, Shu; Xiong, Fei; Yu, Qi-Lin; Zhang, Zi-Yun; Yang, Ping; Liu, Shi-Wei; Eizirik, Decio; Dong, Ling-Li; Sun, Fei; Wang, Cong-Yi.

Mol Ther ; 2024 May 30.

Artigo em Inglês | MEDLINE | ID: mdl-38822524

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Enhanced prime editing systems by manipulating cellular determinants of editing outcomes.

Mapping the genetic landscape of DNA double-strand break repair.

Inducing trained immunity in pro-metastatic macrophages to control tumor metastasis.

Publisher Correction: SERPINB1-mediated checkpoint of inflammatory caspase activation.

SERPINB1-mediated checkpoint of inflammatory caspase activation.

The chemokine CCL1 triggers an AMFR-SPRY1 pathway that promotes differentiation of lung fibroblasts into myofibroblasts and drives pulmonary fibrosis.

Confinement and low adhesion induce fast amoeboid migration of slow mesenchymal cells.

Improving prime editing with an endogenous small RNA-binding protein.

R-loop-dependent promoter-proximal termination ensures genome stability.

Antitumor Î³Î´ T cells need oxygen to function.

Axial Higgs mode detected by quantum pathway interference in RTe₃.

Prime Editing: Precision Genome Editing by Reverse Transcription.

Coding region polyadenylation generates a truncated tRNA synthetase that counters translation repression.

DNA nanomachines reveal an adaptive energy mode in confinement-induced amoeboid migration powered by polarized mitochondrial distribution.

The miR165/166-PHABULOSA module promotes thermotolerance by transcriptionally and posttranslationally regulating HSFA1.

Myosin 9 and N-glycans jointly regulate human papillomavirus entry.

A plasma membrane-localized transporter remobilizes aleurone layer magnesium for seed germination in rice.

A nanopore-based cucumber genome assembly reveals structural variations at two QTLs controlling hypocotyl elongation.

The chemokine CCL1 triggers an AMFR-SPRY1 pathway that promotes differentiation of lung fibroblasts into myofibroblasts and drives pulmonary fibrosis.

PDIA3 orchestrates effector T cell program by serving as a chaperone to facilitate the non-canonical nuclear import of STAT1 and PKM2.