Detalhe da pesquisa
1.
Molecular basis for substrate recruitment to the PRMT5 methylosome.
Mol Cell
; 81(17): 3481-3495.e7, 2021 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34358446
2.
Phosphatidylinositol-5-Phosphate 4-Kinases Regulate Cellular Lipid Metabolism By Facilitating Autophagy.
Mol Cell
; 70(3): 531-544.e9, 2018 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29727621
3.
Transforming Growth Factor-ß Blockade in Pancreatic Cancer Enhances Sensitivity to Combination Chemotherapy.
Gastroenterology
; 165(4): 874-890.e10, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37263309
4.
Development and Characterization of Selective FAK Inhibitors and PROTACs with In Vivo Activity.
Chembiochem
; 24(19): e202300141, 2023 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37088717
5.
Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo.
Nat Chem Biol
; 17(9): 954-963, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33972797
6.
Discovery of a selective inhibitor of doublecortin like kinase 1.
Nat Chem Biol
; 16(6): 635-643, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32251410
7.
The dTAG system for immediate and target-specific protein degradation.
Nat Chem Biol
; 14(5): 431-441, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29581585
8.
A Bi-Directional Carrier Sense Collision Avoidance Neighbor Discovery Algorithm in Directional Wireless Ad Hoc Sensor Networks.
Sensors (Basel)
; 19(9)2019 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31067814
9.
Ratiometric determination of copper(II) using dually emitting Mn(II)-doped ZnS quantum dots as a fluorescent probe.
Mikrochim Acta
; 185(11): 511, 2018 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30343449
10.
Trisomy represses Apc(Min)-mediated tumours in mouse models of Down's syndrome.
Nature
; 451(7174): 73-5, 2008 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-18172498
11.
Spatially Resolved Single-Cell Assessment of Pancreatic Cancer Expression Subtypes Reveals Co-expressor Phenotypes and Extensive Intratumoral Heterogeneity.
Cancer Res
; 83(3): 441-455, 2023 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36459568
12.
NCOA4-Mediated Ferritinophagy Is a Pancreatic Cancer Dependency via Maintenance of Iron Bioavailability for Iron-Sulfur Cluster Proteins.
Cancer Discov
; 12(9): 2180-2197, 2022 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35771492
13.
Coordinated Transcriptional and Catabolic Programs Support Iron-Dependent Adaptation to RAS-MAPK Pathway Inhibition in Pancreatic Cancer.
Cancer Discov
; 12(9): 2198-2219, 2022 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35771494
14.
SMAD4 represses FOSL1 expression and pancreatic cancer metastatic colonization.
Cell Rep
; 36(4): 109443, 2021 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34320363
15.
cIAP1/2 antagonism eliminates MHC class I-negative tumors through T cell-dependent reprogramming of mononuclear phagocytes.
Sci Transl Med
; 13(594)2021 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34011631
16.
Structure-Based Design of a Potent and Selective Covalent Inhibitor for SRC Kinase That Targets a P-Loop Cysteine.
J Med Chem
; 63(4): 1624-1641, 2020 02 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31935084
17.
Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q.
Cell Rep
; 33(11): 108493, 2020 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33326793
18.
CDK7 Inhibition Potentiates Genome Instability Triggering Anti-tumor Immunity in Small Cell Lung Cancer.
Cancer Cell
; 37(1): 37-54.e9, 2020 01 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31883968
19.
PTBP1 enhances exon11a skipping in Mena pre-mRNA to promote migration and invasion in lung carcinoma cells.
Biochim Biophys Acta Gene Regul Mech
; 1862(8): 858-869, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31075540
20.
Single and Dual Targeting of Mutant EGFR with an Allosteric Inhibitor.
Cancer Discov
; 9(7): 926-943, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31092401