Deciphering Discord: How Conflicting Information and Political Ideology Shape Public Attitude Toward PFAS Regulation.

Per- and polyfluorinated substances (PFAS) contamination is an emerging environmental and health risk facing the world. This study examines the impact of conflicting information on Americans' attitude toward PFAS regulation and intention to engage in mitigation behaviors through a one-way, between-subjects experiment. Participants were 1,062 U.S. adults recruited from CloudResearch. Results showed that compared to participants exposed to consistent information, those exposed to conflicting information displayed less favorable attitude toward existing regulation, which led to lower intention to support related policies and to engage in mitigation behaviors. Political ideology moderated these relationships, with stronger experimental effects among conservatives. These findings underscore the importance of conveying consistent risk messages, especially when multiple stakeholders are involved.

Conflicted and Relevant: Systematic Processing of Information on PFAS Contamination.

Per- and polyfluoroalkyl substances (PFAS) contamination is an emerging environmental and public health crisis. Thus, it is crucial to understand public risk perception and communication behaviors surrounding this issue. Guided by the heuristic-systematic model of information processing, this study explores the impact of conflicting information and personal relevance on information insufficiency and information processing. Through an online experiment, 1,062 U.S. adults were randomly assigned to one of four conditions as part of a 2 (information type: conflicting vs. consistent) × 2 (personal relevance: high vs. low) between-subjects factorial design. Both main effect and interaction effect were detected. Specifically, information insufficiency was highest among participants in the high personal relevance and consistent information condition. Personal relevance also had a main effect on information processing. Conflicting information indirectly elevated information processing through increased information insufficiency, but only when personal relevance was low. These findings suggest the importance of providing consistent and personally relevant information related to the risk of PFAS contamination.

Comparative risk perception of the monkeypox outbreak and the monkeypox vaccine.

Based on survey data collected from a nationally representative sample (N = 1,000), this study applies the psychometric paradigm to demonstrate that the American public perceived the monkeypox outbreak as a more dreaded risk than the monkeypox vaccine, but they also viewed the monkeypox vaccine as a more unknown risk. These perceptions influenced their overall risk judgment toward the monkeypox outbreak, support for public health responses and government assistance measures, and likelihood to get vaccinated. Contributing to research on risk perception, these findings indicate that the dread and unknown dimensions offer a more intricate assessment of risk perception beyond perceived susceptibility and perceived severity. Guiding risk communication practice, these results suggest that it is important to highlight to the public that the monkeypox vaccine is a mature technology and getting vaccinated before exposure provides the best protection for high-risk populations.

It Takes Two to Tango: How Ability and Morality Shape Consumers' Willingness to Refill and Reuse.

The waste problem in the U.S. has only intensified in recent years, first due to China's National Sword Policy and then to the COVID-19 pandemic. One solution to this problem is to encourage people to adopt pro-environmental behaviors such as opting for reusables and products with plastic-free alternate packaging. In this study, we employ the value-belief-norm theory to examine whether its proposed causal chain predicts consumers' willingness to use reusables and products with plastic-free alternate packaging. We also explore the moderating role of perceived behavior control, one of the strongest predictors of environmental behaviors. Our research provides support to the value-belief-norm theory in predicting behavioral willingness. The moderating role of perceived behavior control provides additional insight into the theoretical model and furnishes practical implications for strategic communication designed to encourage the adoption of reusables and alternative packaging.

Communicating Per- and Polyfluoroalkyl Substances (PFAS) Contamination to the Public Through Personal Relevance.

It is important to understand people's risk perception to identify effective pathways for risk communication about per- and polyfluoroalkyl substances (PFAS) because they present emerging environmental health risks. Guided by dual-process theories of information processing, this study focuses on personal relevance as a key variable that influences risk perception, systematic processing, and information seeking intention. Through an experimental survey, we found that participants in the high personal relevance condition (n = 497) were more likely to process information systematically compared to those in the low personal relevance condition (n = 486). Results also revealed that personal relevance influenced systematic processing through risk judgment and emotional response. Message-specific systematic processing was positively associated with information seeking intention. Lastly, trust in government and trust in science had different relationships with systematic processing, demonstrating the importance of distinguishing different types of institutional trust in future research.

PFAS Contamination: Pathway from Communication to Behavioral Outcomes.

ABSTRACTGuided by the risk information seeking and processing model, this study examines social cognitive variables that motivate individuals to actively seek and process information related to per- and polyfluoroalkyl substances (PFAS) contamination. Results indicate that information insufficiency, affective response, and informational subjective norms are positively related to information seeking and systematic processing, which are positively associated with policy support and intention to adopt risk mitigation behaviors. These findings suggest that when communicating the health risks of PFAS contamination to the general public, cognitive, affective, and normative factors are important initial steps to generate public interest in relevant information.

Public Support for COVID-19 Responses: Cultural Cognition, Risk Perception, and Emotions.

As one of the biggest challenges facing mankind in recent history, the COVID-19 pandemic has had profound impact on the United States. However, government responses ranging from stay-at-home orders to temporary closing of nonessential businesses are not palatable for everyone. This study examines how cultural cognition, risk perception, and discrete emotions influence Americans' support for COVID-19 responses. We found that compared to communitarians and egalitarians, individualists and hierarchists were less likely to support COVID-19 responses. In addition, fear and anger mediated the relationship between risk perception and public support in the opposite direction. The highlight of this study is the moderating role of cultural cognition. Specifically, individualistic worldviews significantly moderated anger's mediation effect on the relationship between risk perception and support for COVID-19 responses.

It's the Thoughts That Count: How Psychological Distance and Affect Heuristic Influence Support for Aid Response Measures During the COVID-19 Pandemic.

Guided by construal level-theory, this research seeks to understand the effect of perceived psychological distance on emotions and risk perception associated with the COVID-19 pandemic in its early stage. Survey data were collected from a nationally representative U.S. adult sample (N = 1009) in April 2020. Results reveal that social distance was negatively related to emotions and risk perception. However, hypothetical distance was not significantly related to these variables. Emotions and risk perception also mediated the relationship between social distance and support for aid response measures; theoretically, we demonstrate that people evaluate risks contingent on their emotions when making decisions. This research contributes to extant literature on psychological distance and its utility in communication messaging design during public health crises.

Narrative persuasion and psychological distance: Analyzing the effectiveness of distance-framed narratives in communicating ocean plastic pollution.

Narratives have been identified as an effective tool to communicate seemingly abstract and uncertain risks. This study integrates the construal level theory of psychological distance and narrative persuasion to examine how distance-framed narratives influence young adults' attitude, behavioral intention, and policy support related to ocean plastic pollution. Results from an experimental survey (N = 889) indicate that the narrative featuring socially close characters and spatially close location is least effective in producing persuasive effects. Instead, the narrative depicting socially close characters' encounters at a spatially distant location is more persuasive. Within narrative conditions, the findings support the mediating role of identification and transportation in facilitating narrative effects. Serial mediation of identification/transportation and psychological distance perception was also observed. Findings from this study offer meaningful theoretical and practical implications for strategic communication on ocean plastic pollution.

Official sources, news outlets, or search engines? Rumour validation on social media during Hurricanes Harvey and Irma.

This study, based on data collected from a representative sample of adults in the United States, explores the social cognitive variables that motivated Americans to validate rumours on social media about Hurricanes Harvey and Irma, both of which struck in August/September 2017. The results indicate that risk perception and negative emotions are positively related to systematic processing of relevant risk information, and that systematic processing is significantly related to rumour validation through search engines such as Google. In contrast, trust in information about the hurricane is significantly related to validation through official sources, such as FEMA (Federal Emergency Management Agency), and major news outlets such as The New York Times. Trust in information is also significantly related to systematic processing of risk information. The findings of this study suggest that ordinary citizens may be motivated to validate rumours on social media, which is an increasingly important issue in contemporary societies.

Titratable transmembrane residues and a hydrophobic plug are essential for manganese import via the Bacillus anthracis ABC transporter MntBC-A.

All extant life forms require trace transition metals (e.g., Fe2/3+, Cu1/2+, and Mn2+) to survive. However, as these are environmentally scarce, organisms have evolved sophisticated metal uptake machineries. In bacteria, high-affinity import of transition metals is predominantly mediated by ABC transporters. During bacterial infection, sequestration of metal by the host further limits the availability of these ions, and accordingly, bacterial ABC transporters (importers) of metals are key virulence determinants. However, the structure-function relationships of these metal transporters have not been fully elucidated. Here, we used metal-sensitivity assays, advanced structural modeling, and enzymatic assays to study the ABC transporter MntBC-A, a virulence determinant of the bacterial human pathogen Bacillus anthracis. We find that despite its broad metal-recognition profile, MntBC-A imports only manganese, whereas zinc can function as a high-affinity inhibitor of MntBC-A. Computational analysis shows that the transmembrane metal permeation pathway is lined with six titratable residues that can coordinate the positively charged metal, and mutagenesis studies show that they are essential for manganese transport. Modeling suggests that access to these titratable residues is blocked by a ladder of hydrophobic residues, and ATP-driven conformational changes open and close this hydrophobic seal to permit metal binding and release. The conservation of this arrangement of titratable and hydrophobic residues among ABC transporters of transition metals suggests a common mechanism. These findings advance our understanding of transmembrane metal recognition and permeation and may aid the design and development of novel antibacterial agents.

Misinformation, Anticipated Regret, and Vaccine-Related Behaviors.

A national survey (N = 1025) conducted in August 2021 reveals that Americans' belief in misinformation about COVID-19 was negatively associated with vaccine acceptance. Importantly, the more participants believe in misinformation, the less anticipated regret they experience for not getting vaccinated. Reduced anticipated regret is associated with lower levels of vaccination intention and vaccine acceptance. To counteract the negative impact of misinformation, this study reveals the potential of an under-researched emotion in overcoming vaccine hesitancy.

Comparative Risk: Dread and Unknown Characteristics of the COVID-19 Pandemic Versus COVID-19 Vaccines.

This research characterizes risk perceptions of the COVID-19 pandemic and the COVID-19 vaccines based on the dread and unknown dimensions of the psychometric paradigm. We examine if mental risk comparisons of these two risk objects influence risk mitigation behaviors (vaccination intention; vaccine acceptance; preventive behaviors) and emotional responses among unvaccinated and vaccinated Americans. A survey (N = 1532) was conducted based on a nationally representative sample of U.S. adults in May 2021. Results reveal considerable impact of risk comparison, especially along the dread dimension, on the outcomes of interest. In essence, this research reveals critical insights regarding vaccine hesitancy and risk communication about vaccination.

Predicting Recycling Behavior in New York State: an integrated model.

Public participation in proper recycling is a crucial means to deal with the crisis in the U.S. recycling market. In this study, we combine the norm activation model (NAM; Schwartz 1977), the information-motivation-behavioral skills model (IMB; Fisher et al. 2003), and the theory of interpersonal behavior (TIB; Triandis 1977; 1979) to investigate recycling intention and behavior. Based on a longitudinal sample of New York state residents (N = 520), the results show that the integrated model fits the data well. Personal norm, habit, and recycling intention are three direct predictors of recycling behavior. Recycling intention is directly influenced by personal norm and behavioral skills, and indirectly influenced by personal motivation, social motivation, and ascription of responsibility. These findings suggest the importance of the normative approach in environmental campaigns to encourage recycling.

Substrate recognition and ATPase activity of the E. coli cysteine/cystine ABC transporter YecSC-FliY.

Sulfur is essential for biological processes such as amino acid biogenesis, iron-sulfur cluster formation, and redox homeostasis. To acquire sulfur-containing compounds from the environment, bacteria have evolved high-affinity uptake systems, predominant among which is the ABC transporter family. Theses membrane-embedded enzymes use the energy of ATP hydrolysis for transmembrane transport of a wide range of biomolecules against concentration gradients. Three distinct bacterial ABC import systems of sulfur-containing compounds have been identified, but the molecular details of their transport mechanism remain poorly characterized. Here we provide results from a biochemical analysis of the purified Escherichia coli YecSC-FliY cysteine/cystine import system. We found that the substrate-binding protein FliY binds l-cystine, l-cysteine, and d-cysteine with micromolar affinities. However, binding of the l- and d-enantiomers induced different conformational changes of FliY, where the l- enantiomer-substrate-binding protein complex interacted more efficiently with the YecSC transporter. YecSC had low basal ATPase activity that was moderately stimulated by apo FliY, more strongly by d-cysteine-bound FliY, and maximally by l-cysteine- or l-cystine-bound FliY. However, at high FliY concentrations, YecSC reached maximal ATPase rates independent of the presence or nature of the substrate. These results suggest that FliY exists in a conformational equilibrium between an open, unliganded form that does not bind to the YecSC transporter and closed, unliganded and closed, liganded forms that bind this transporter with variable affinities but equally stimulate its ATPase activity. These findings differ from previous observations for similar ABC transporters, highlighting the extent of mechanistic diversity in this large protein family.

Predicting the U.S. Public's Prosocial Responses during the COVID-19 Pandemic.

This research examines three distinct processes that influence Americans' prosocial responses during the COVID-19 pandemic. Employing a nationally representative sample, participants read either a mock-up news article on COVID-19 with a clear responsibility attribution (n = 496) or one without (n = 513) in a survey embedded experiment. Participants exposed to the responsibility attribution condition engaged in less systematic processing; systematic processing and all emotions mediated the relationship between responsibility attribution and support for government response measures. For donation intention, only systematic processing and the two socially oriented emotions were significant mediators. In essence, responsibility attribution in media coverage can exert powerful influence on public perception in an ongoing crisis.

In the Wake of Scandals: How Media Use and Social Trust Influence Risk Perception and Vaccination Intention among Chinese Parents.

Recently, repeated childhood vaccine scandals shook public confidence in vaccine safety in China. This study explores whether media attention, online discussion, and social trust influence Chinese parents' risk perception and vaccination intention. Based on data from a Qualtrics panel (N = 354), results indicate that media attention is positively related to social trust and online discussion is positively related to perceived benefits. Additionally, social trust is negatively associated with perceived risk but positively associated with perceived benefits. Social trust is also positively related to general vaccination intention and intention to get domestic vaccines. Further, social trust mediates the relationship between media attention/online discussion and risk perception. Lastly, parents with higher risk perception are less likely to get domestic vaccines, but more likely to get imported vaccines. Perceived benefits also influence vaccination intention.

Fast and Frugal: Information Processing Related to The Coronavirus Pandemic.

This research focuses on three factors that influence how individuals cognitively process information related to the coronavirus outbreak. Guided by dual-process theories of information processing, we establish how the two different information processing modes (system 1: heuristic processing; system 2: systematic processing) are influenced by individuals' responsibility attribution, discrete negative emotions, and risk perception. In an experiment, participants were exposed to a news article that either blames China (n = 445) or does not blame China (n = 498) for the pandemic. Results reveal that exposure to the responsibility attribution frame led individuals to engage in more heuristic processing, but it did not influence systematic processing. Discrete negative emotions and risk perception mediated the relationship between responsibility attribution and information processing. The indirect relationships suggest a more intricate process underlying heuristic processing and systematic processing. In particular, information processing styles seem to be determined by social judgment surrounding the coronavirus pandemic.

Closer to the Heart, Closer to the Mind: Using Psychological Distance to Communicate a Measles Outbreak.

Psychological distance can influence a variety of risk-related perceptions and behaviors. This study (N = 205) examines the effect of spatial distance manipulation on emotions, risk perception, and behavioral intention following a recent measles outbreak in the United States. Results indicate that experimentally induced spatial distance influences emotional intensity, which affects psychological distance perception. Perceived distance subsequently influences risk perception, while emotions influence information engagement and support for mandatory vaccination.

The Role of Temporal Distance Perception in Narrative vs. Non-Narrative Persuasion Related to E-Cigarettes.

Research has long identified narrative persuasion as an effective health communication strategy. This study explores temporal distance perception, which is the perceived distance of a health threat, as a possible psychological mechanism through which narrative persuasion influences young adults' attitude and behavioral intention related to e-cigarette use. When reading the narrative message featuring negative consequences of nicotine addiction, participants demonstrate a higher level of transportation and subsequently perceive the health threat related to e-cigarette as temporally closer. The shortened temporal distance perception, along with transportation, mediates the relationship between exposure to the narrative message and participants' attitude and behavioral intention. Participants' past experience also plays an important role. In particular, participants who have not used e-cigarette before report more negative attitude after reading the narrative message. Findings of the current study indicate that narrative persuasion may be an effective strategy to deter young adults from using e-cigarettes.