Detalhe da pesquisa
1.
Perinuclear Anchoring of H3K9-Methylated Chromatin Stabilizes Induced Cell Fate in C. elegans Embryos.
Cell
; 163(6): 1333-47, 2015 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26607792
2.
Safety and efficacy of an anti-human APC antibody for prophylaxis of congenital factor deficiencies in preclinical models.
Blood
; 142(12): 1071-1081, 2023 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37294924
3.
Caspase-6-cleaved tau is relevant in Alzheimer's disease and marginal in four-repeat tauopathies: Diagnostic and therapeutic implications.
Neuropathol Appl Neurobiol
; 48(5): e12819, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35508761
4.
Therapeutic Development of Immune Checkpoint Inhibitors.
Adv Exp Med Biol
; 1248: 619-649, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32185726
5.
Selective inhibition of Ezh2 by a small molecule inhibitor blocks tumor cells proliferation.
Proc Natl Acad Sci U S A
; 109(52): 21360-5, 2012 Dec 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-23236167
6.
Ablation of calcineurin Aß reveals hyperlipidemia and signaling cross-talks with phosphodiesterases.
J Biol Chem
; 288(5): 3477-88, 2013 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23258544
7.
Characterization of 405B8H3(D-E), a newly engineered high affinity chimeric LAG-3 antibody with potent antitumor activity.
FEBS Open Bio
; 13(7): 1253-1265, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37302810
8.
High-throughput optofluidic screening of single B cells identifies novel cross-reactive antibodies as inhibitors of uPAR with antibody-dependent effector functions.
MAbs
; 15(1): 2184197, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36859773
9.
Development of a fully human anti-GITR antibody with potent antitumor activity using H2L2 mice.
FEBS Open Bio
; 12(8): 1542-1557, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35674216
10.
Development and characterization of a novel human CD137 agonistic antibody with anti-tumor activity and a good safety profile in non-human primates.
FEBS Open Bio
; 12(12): 2166-2178, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36176235
11.
Developing high-affinity decoy receptors to treat multiple myeloma and diffuse large B cell lymphoma.
J Exp Med
; 219(9)2022 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35881112
12.
Preclinical efficacy and toxicity studies of a highly specific chimeric anti-CD47 antibody.
FEBS Open Bio
; 11(3): 813-825, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33449453
13.
Generation and characterization of a high-affinity chimeric anti-OX40 antibody with potent antitumor activity.
FEBS Lett
; 595(11): 1587-1603, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33792041
14.
Neutralization of PD-L2 is Essential for Overcoming Immune Checkpoint Blockade Resistance in Ovarian Cancer.
Clin Cancer Res
; 27(15): 4435-4448, 2021 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34011561
15.
Requirement of transcription factor NFAT in developing atrial myocardium.
J Cell Biol
; 161(5): 861-74, 2003 Jun 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-12796475
16.
Role of transcription factor NFAT in glucose and insulin homeostasis.
Mol Cell Biol
; 26(20): 7372-87, 2006 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16908540
17.
Study of the interactions of a novel monoclonal antibody, mAb059c, with the hPD-1 receptor.
Sci Rep
; 9(1): 17830, 2019 11 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31780710
18.
Recruitment of the extracellular signal-regulated kinase/ribosomal S6 kinase signaling pathway to the NFATc4 transcription activation complex.
Mol Cell Biol
; 25(3): 907-20, 2005 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-15657420
19.
Phosphorylation of NFATc4 by p38 mitogen-activated protein kinases.
Mol Cell Biol
; 22(11): 3892-904, 2002 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-11997522
20.
Alpha-tocopherol decreases superoxide anion release in human monocytes under hyperglycemic conditions via inhibition of protein kinase C-alpha.
Diabetes
; 51(10): 3049-54, 2002 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-12351446