Pesquisa | BVS Violência e Saúde

1.

Microfluidic Squeezing Enables MHC Class I Antigen Presentation by Diverse Immune Cells to Elicit CD8⁺ T Cell Responses with Antitumor Activity.

Booty, Matthew G; Hlavaty, Kelan A; Stockmann, Adam; Ozay, Emrah Ilker; Smith, Carolyne; Tian, Lina; How, Edylle; Subramanya, Disha; Venkitaraman, Anita; Yee, Christian; Pryor, Olivia; Volk, Kelly; Blagovic, Katarina; Vicente-Suarez, Ildefonso; Yarar, Defne; Myint, Melissa; Merino, Amy; Chow, Jonathan; Abdeljawad, Tarek; An, Harry; Liu, Sophia; Mao, Shirley; Heimann, Megan; Talarico, LeeAnn; Jacques, Miye K; Chong, Eritza; Pomerance, Lucas; Gonzalez, John T; von Andrian, Ulrich H; Jensen, Klavs F; Langer, Robert; Knoetgen, Hendrik; Trumpfheller, Christine; Umaña, Pablo; Bernstein, Howard; Sharei, Armon; Loughhead, Scott M.

J Immunol ; 208(4): 929-940, 2022 02 15.

Artigo em Inglês | MEDLINE | ID: mdl-35091434

2.

SNX9 couples actin assembly to phosphoinositide signals and is required for membrane remodeling during endocytosis.

Yarar, Defne; Waterman-Storer, Clare M; Schmid, Sandra L.

Dev Cell ; 13(1): 43-56, 2007 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-17609109

3.

The type III effector EspF coordinates membrane trafficking by the spatiotemporal activation of two eukaryotic signaling pathways.

Alto, Neal M; Weflen, Andrew W; Rardin, Matthew J; Yarar, Defne; Lazar, Cheri S; Tonikian, Raffi; Koller, Antonius; Taylor, Susan S; Boone, Charles; Sidhu, Sachdev S; Schmid, Sandra L; Hecht, Gail A; Dixon, Jack E.

J Cell Biol ; 178(7): 1265-78, 2007 Sep 24.

Artigo em Inglês | MEDLINE | ID: mdl-17893247

4.

Cargo and dynamin regulate clathrin-coated pit maturation.

Loerke, Dinah; Mettlen, Marcel; Yarar, Defne; Jaqaman, Khuloud; Jaqaman, Henry; Danuser, Gaudenz; Schmid, Sandra L.

PLoS Biol ; 7(3): e57, 2009 Mar 17.

Artigo em Inglês | MEDLINE | ID: mdl-19296720

5.

Engineered red blood cells (activating antigen carriers) drive potent T cell responses and tumor regression in mice.

Blagovic, Katarina; Smith, Carolyne K; Ramakrishnan, Amritha; Moore, Lindsay; Soto, David R; Thompson, Zachary; Stockmann, Adam P; Kruszelnicki, Sonia; Thakkar, Akshi; Murray, Jason; Torres, Sebastian; Wondimagegnhu, Bersabel; Yi, Roslyn; Dadgar, Maisam; Paracha, Abdul M; Page, Claire; Clear, Louise; Chaudhry, Omer A; Myint, Melissa; Bridgen, Devin T; Gilbert, Jonathan B; Seidl, Katherine J; Sharei, Armon; Loughhead, Scott; Bernstein, Howard; Yarar, Defne.

Front Immunol ; 13: 1015585, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-36263022

6.

Event ordering in live-cell imaging determined from temporal cross-correlation asymmetry.

Sisan, Daniel R; Yarar, Defne; Waterman, Clare M; Urbach, Jeffrey S.

Biophys J ; 98(11): 2432-41, 2010 Jun 02.

Artigo em Inglês | MEDLINE | ID: mdl-20513386

7.

Formation of filopodia-like bundles in vitro from a dendritic network.

Vignjevic, Danijela; Yarar, Defne; Welch, Matthew D; Peloquin, John; Svitkina, Tatyana; Borisy, Gary G.

J Cell Biol ; 160(6): 951-62, 2003 Mar 17.

Artigo em Inglês | MEDLINE | ID: mdl-12642617

8.

SNX9 regulates dynamin assembly and is required for efficient clathrin-mediated endocytosis.

Soulet, Fabienne; Yarar, Defne; Leonard, Marilyn; Schmid, Sandra L.

Mol Biol Cell ; 16(4): 2058-67, 2005 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-15703209

9.

A dynamic actin cytoskeleton functions at multiple stages of clathrin-mediated endocytosis.

Yarar, Defne; Waterman-Storer, Clare M; Schmid, Sandra L.

Mol Biol Cell ; 16(2): 964-75, 2005 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-15601897

10.

An assembly-incompetent mutant establishes a requirement for dynamin self-assembly in clathrin-mediated endocytosis in vivo.

Song, Byeong Doo; Yarar, Defne; Schmid, Sandra L.

Mol Biol Cell ; 15(5): 2243-52, 2004 May.

Artigo em Inglês | MEDLINE | ID: mdl-15004222

11.

Motility determinants in WASP family proteins.

Yarar, Defne; D'Alessio, Joseph A; Jeng, Robert L; Welch, Matthew D.

Mol Biol Cell ; 13(11): 4045-59, 2002 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-12429845

12.

Systems biology driving drug development: from design to the clinical testing of the anti-ErbB3 antibody seribantumab (MM-121).

Schoeberl, Birgit; Kudla, Art; Masson, Kristina; Kalra, Ashish; Curley, Michael; Finn, Gregory; Pace, Emily; Harms, Brian; Kim, Jaeyeon; Kearns, Jeff; Fulgham, Aaron; Burenkova, Olga; Grantcharova, Viara; Yarar, Defne; Paragas, Violette; Fitzgerald, Jonathan; Wainszelbaum, Marisa; West, Kip; Mathews, Sara; Nering, Rachel; Adiwijaya, Bambang; Garcia, Gabriela; Kubasek, Bill; Moyo, Victor; Czibere, Akos; Nielsen, Ulrik B; MacBeath, Gavin.

NPJ Syst Biol Appl ; 3: 16034, 2017.

Artigo em Inglês | MEDLINE | ID: mdl-28725482

13.

Heregulin-ErbB3-Driven Tumor Growth Persists in PI3 Kinase Mutant Cancer Cells.

Yarar, Defne; Lahdenranta, Johanna; Kubasek, William; Nielsen, Ulrik B; MacBeath, Gavin.

Mol Cancer Ther ; 14(9): 2072-80, 2015 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-26116360

14.

Kinetochore genes are coordinately up-regulated in human tumors as part of a FoxM1-related cell division program.

Thiru, Prathapan; Kern, David M; McKinley, Kara L; Monda, Julie K; Rago, Florencia; Su, Kuan-Chung; Tsinman, Tonia; Yarar, Defne; Bell, George W; Cheeseman, Iain M.

Mol Biol Cell ; 25(13): 1983-94, 2014 Jul 01.

Artigo em Inglês | MEDLINE | ID: mdl-24829384

15.

Computational modeling of ERBB2-amplified breast cancer identifies combined ErbB2/3 blockade as superior to the combination of MEK and AKT inhibitors.

Kirouac, Daniel C; Du, Jin Y; Lahdenranta, Johanna; Overland, Ryan; Yarar, Defne; Paragas, Violette; Pace, Emily; McDonagh, Charlotte F; Nielsen, Ulrik B; Onsum, Matthew D.

Sci Signal ; 6(288): ra68, 2013 Aug 13.

Artigo em Inglês | MEDLINE | ID: mdl-23943608

16.

Differential requirements for clathrin-dependent endocytosis at sites of cell-substrate adhesion.

Batchelder, Erika M; Yarar, Defne.

Mol Biol Cell ; 21(17): 3070-9, 2010 Sep 01.

Artigo em Inglês | MEDLINE | ID: mdl-20631253

17.

Cargo- and adaptor-specific mechanisms regulate clathrin-mediated endocytosis.

Mettlen, Marcel; Loerke, Dinah; Yarar, Defne; Danuser, Gaudenz; Schmid, Sandra L.

J Cell Biol ; 188(6): 919-33, 2010 Mar 22.

Artigo em Inglês | MEDLINE | ID: mdl-20231386

18.

SNX9 activities are regulated by multiple phosphoinositides through both PX and BAR domains.

Yarar, Defne; Surka, Mark C; Leonard, Marilyn C; Schmid, Sandra L.

Traffic ; 9(1): 133-46, 2008 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-17988218

19.

Cortical patches on the move.

Yarar, Defne.

Cell ; 115(4): 373-5, 2003 Nov 14.

Artigo em Inglês | MEDLINE | ID: mdl-14622592

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