1.
Org Biomol Chem
; 13(17): 4855-8, 2015 May 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25832795
RESUMO
A novel method for the C-C bond cleavage of cyclopropanes was developed by gold-catalyzed cycloisomerization of 2-(1-alkynyl-cyclopropyl)pyridine with nucleophiles, which provides efficient access to structurally diverse indolizines under mild conditions. A series of N-, C- and O-based nucleophiles were involved in this reaction to afford the corresponding indolizines in modest to excellent yields.
2.
Angew Chem Int Ed Engl
; 54(38): 11205-8, 2015 Sep 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26245887
RESUMO
The enantioselective redox annulation of nitroalkynes with indoles is enabled by gold/chiral phosphoric acid dual catalysis. A range of indolin-3-one derivatives bearing quaternary stereocenters at the C2â position were afforded in good yields and excellent enantioselectivities (up to 96 %â ee) from readily available starting materials.