Detalhe da pesquisa
1.
Insulin enhances the biogenesis of nuclear sterol regulatory element-binding protein (SREBP)-1c by posttranscriptional down-regulation of Insig-2A and its dissociation from SREBP cleavage-activating protein (SCAP).SREBP-1c complex.
J Biol Chem
; 284(46): 31726-34, 2009 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-19759400
2.
SREBPs: the crossroads of physiological and pathological lipid homeostasis.
Trends Endocrinol Metab
; 19(2): 65-73, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-18291668
3.
Thiol alkylation inhibits the mitogenic effects of platelet-derived growth factor and renders it proapoptotic via activation of STATs and p53 and induction of expression of caspase1 and p21(waf1/cip1).
Oncogene
; 22(1): 117-30, 2003 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-12527914
4.
Dysregulation of sterol regulatory element binding protein-1c in livers of morbidly obese women is associated with altered suppressor of cytokine signaling-3 and signal transducer and activator of transcription-1 signaling.
Metabolism
; 59(4): 587-98, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19913854
5.
Insulin enhances post-translational processing of nascent SREBP-1c by promoting its phosphorylation and association with COPII vesicles.
J Biol Chem
; 284(12): 7518-32, 2009 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-19158095
6.
Hepatic gene expression in morbidly obese women: implications for disease susceptibility.
Obesity (Silver Spring)
; 17(8): 1563-73, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19265796
7.
Expression of the rat sterol regulatory element-binding protein-1c gene in response to insulin is mediated by increased transactivating capacity of specificity protein 1 (Sp1).
J Biol Chem
; 282(24): 17517-29, 2007 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17449871
8.
Posttranslational processing of SREBP-1 in rat hepatocytes is regulated by insulin and cAMP.
Biochem Biophys Res Commun
; 332(1): 174-80, 2005 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-15896314
9.
Cytosolic phospholipase A2 is an effector of Jak/STAT signaling and is involved in platelet-derived growth factor BB-induced growth in vascular smooth muscle cells.
J Biol Chem
; 278(11): 9986-92, 2003 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-12529382
10.
A requirement for calcium-independent phospholipase A2 in thrombin-induced arachidonic acid release and growth in vascular smooth muscle cells.
J Biol Chem
; 278(44): 43831-7, 2003 Oct 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-12928445
11.
Arachidonic acid activation of translation initiation signaling in vascular smooth muscle cells.
Biochem Biophys Res Commun
; 309(4): 755-61, 2003 Oct 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-13679036
12.
5(S)-hydroxyeicosatetraenoic acid stimulates DNA synthesis in human microvascular endothelial cells via activation of Jak/STAT and phosphatidylinositol 3-kinase/Akt signaling, leading to induction of expression of basic fibroblast growth factor 2.
J Biol Chem
; 277(43): 41213-9, 2002 Oct 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-12193593
13.
N-Ethylmaleimide inhibits platelet-derived growth factor BB-stimulated Akt phosphorylation via activation of protein phosphatase 2A.
J Biol Chem
; 277(42): 40148-55, 2002 Oct 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-12171932
14.
A potential role for nuclear factor of activated T-cells in receptor tyrosine kinase and G-protein-coupled receptor agonist-induced cell proliferation.
Biochem J
; 368(Pt 1): 183-90, 2002 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12188924