Pesquisa | BVS Violência e Saúde

1.

A type I interferon regulatory network for human plasmacytoid dendritic cells based on heparin, membrane-bound and soluble BDCA-2.

Venegas-Solis, Francisco; Staliunaite, Laura; Rudolph, Elisa; Münch, Carina Chan-Song; Yu, Philipp; Freibert, Sven-A; Maeda, Takahiro; Zimmer, Christine L; Möbs, Christian; Keller, Christian; Kaufmann, Andreas; Bauer, Stefan.

Proc Natl Acad Sci U S A ; 121(12): e2312404121, 2024 Mar 19.

Artigo em Inglês | MEDLINE | ID: mdl-38478694

2.

Nucleic acid-sensing Toll-like receptors are essential for the control of endogenous retrovirus viremia and ERV-induced tumors.

Yu, Philipp; Lübben, Wolger; Slomka, Heike; Gebler, Janine; Konert, Madlen; Cai, Chengcong; Neubrandt, Luisa; Prazeres da Costa, Olivia; Paul, Stephanie; Dehnert, Sonja; Döhne, Karolin; Thanisch, Michael; Storsberg, Silke; Wiegand, Lisa; Kaufmann, Andreas; Nain, Marianne; Quintanilla-Martinez, Leticia; Bettio, Sabrina; Schnierle, Barbara; Kolesnikova, Larissa; Becker, Stephan; Schnare, Markus; Bauer, Stefan.

Immunity ; 37(5): 867-79, 2012 Nov 16.

Artigo em Inglês | MEDLINE | ID: mdl-23142781

3.

The potential role of retroviruses in autoimmunity.

Yu, Philipp.

Immunol Rev ; 269(1): 85-99, 2016 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-26683147

4.

The Extracellular Domains of IgG1 and T Cell-Derived IL-4/IL-13 Are Critical for the Polyclonal Memory IgE Response In Vivo.

Turqueti-Neves, Adriana; Otte, Manuel; Schwartz, Christian; Schmitt, Michaela Erika Renate; Lindner, Cornelia; Pabst, Oliver; Yu, Philipp; Voehringer, David.

PLoS Biol ; 13(11): e1002290, 2015.

Artigo em Inglês | MEDLINE | ID: mdl-26523376

5.

Basophil-mediated protection against gastrointestinal helminths requires IgE-induced cytokine secretion.

Schwartz, Christian; Turqueti-Neves, Adriana; Hartmann, Susanne; Yu, Philipp; Nimmerjahn, Falk; Voehringer, David.

Proc Natl Acad Sci U S A ; 111(48): E5169-77, 2014 Dec 02.

Artigo em Inglês | MEDLINE | ID: mdl-25404305

6.

Tumor suppressor role of phospholipase C epsilon in Ras-triggered cancers.

Martins, Marta; McCarthy, Afshan; Baxendale, Rhona; Guichard, Sabrina; Magno, Lorenza; Kessaris, Nicoletta; El-Bahrawy, Mona; Yu, Philipp; Katan, Matilda.

Proc Natl Acad Sci U S A ; 111(11): 4239-44, 2014 Mar 18.

Artigo em Inglês | MEDLINE | ID: mdl-24591640

7.

APOBEC3 enzymes restrict marginal zone B cells.

Beck-Engeser, Gabriele B; Winkelmann, Rebecca; Wheeler, Matthew L; Shansab, Maryam; Yu, Philipp; Wünsche, Sarah; Walchhütter, Anja; Metzner, Mirjam; Vettermann, Christian; Eilat, Dan; DeFranco, Anthony; Jäck, Hans-Martin; Wabl, Matthias.

Eur J Immunol ; 45(3): 695-704, 2015 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-25501566

8.

A hypomorphic IgH-chain allele affects development of B-cell subsets and favours receptor editing.

Brenner, Sven; Drewel, Diana; Steinbart, Thomas; Weisel, Florian; Härtel, Eric; Pötzsch, Sonja; Welzel, Heike; Brandl, Andreas; Yu, Philipp; Mudde, Geert C; Schweizer, Astrid; Nitschke, Lars; Winkler, Thomas H.

EMBO J ; 30(13): 2705-18, 2011 May 27.

Artigo em Inglês | MEDLINE | ID: mdl-21623346

9.

IgE knock-in mice suggest a role for high levels of IgE in basophil-mediated active systemic anaphylaxis.

Lübben, Wolger; Turqueti-Neves, Adriana; Okhrimenko, Anna; Stöberl, Christian; Schmidt, Volker; Pfeffer, Klaus; Dehnert, Sonja; Wünsche, Sarah; Storsberg, Silke; Paul, Stefanie; Bauer, Stefan; Riethmüller, Gert; Voehringer, David; Yu, Philipp.

Eur J Immunol ; 43(5): 1231-42, 2013 May.

Artigo em Inglês | MEDLINE | ID: mdl-23423996

10.

Motor, Cognitive, and Behavioral Impairment in TLR3 and TLR9 Deficient Male Mice: Insights into the Non-Immunological Roles of Toll-Like Receptors.

Vargas-Calderón, Héctor; Ortega-Robles, Emmanuel; Rocha, Luisa; Yu, Philipp; Arias-Carrión, Oscar.

Arch Med Res ; 55(3): 102985, 2024 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-38520880

11.

T-bet⁺ B cells are activated by and control endogenous retroviruses through TLR-dependent mechanisms.

Rauch, Eileen; Amendt, Timm; Lopez Krol, Aleksandra; Lang, Fabian B; Linse, Vincent; Hohmann, Michelle; Keim, Ann-Christin; Kreutzer, Susanne; Kawengian, Kevin; Buchholz, Malte; Duschner, Philipp; Grauer, Saskia; Schnierle, Barbara; Ruhl, Andreas; Burtscher, Ingo; Dehnert, Sonja; Kuria, Chege; Kupke, Alexandra; Paul, Stephanie; Liehr, Thomas; Lechner, Marcus; Schnare, Markus; Kaufmann, Andreas; Huber, Magdalena; Winkler, Thomas H; Bauer, Stefan; Yu, Philipp.

Nat Commun ; 15(1): 1229, 2024 Feb 09.

Artigo em Inglês | MEDLINE | ID: mdl-38336876

12.

TLR7 and IgM: Dangerous Partners in Autoimmunity.

Amendt, Timm; Yu, Philipp.

Antibodies (Basel) ; 12(1)2023 Jan 06.

Artigo em Inglês | MEDLINE | ID: mdl-36648888

13.

A novel N-ethyl-N-nitrosourea-induced mutation in phospholipase CÎ³2 causes inflammatory arthritis, metabolic defects, and male infertility in vitro in a murine model.

Abe, Koichiro; Fuchs, Helmut; Boersma, Auke; Hans, Wolfgang; Yu, Philipp; Kalaydjiev, Svetoslav; Klaften, Matthias; Adler, Thure; Calzada-Wack, Julia; Mossbrugger, Ilona; Rathkolb, Birgit; Rozman, Jan; Prehn, Cornelia; Maraslioglu, Miriam; Kametani, Yoshie; Shimada, Shin; Adamski, Jerzy; Busch, Dirk H; Esposito, Irene; Klingenspor, Martin; Wolf, Eckhard; Wurst, Wolfgang; Gailus-Durner, Valerie; Katan, Matilda; Marschall, Susan; Soewarto, Dian; Wagner, Sibylle; de Angelis, Martin Hrabe.

Arthritis Rheum ; 63(5): 1301-11, 2011 May.

Artigo em Inglês | MEDLINE | ID: mdl-21305534

14.

Characterization of phospholipase C gamma enzymes with gain-of-function mutations.

Everett, Katy L; Bunney, Tom D; Yoon, Youngdae; Rodrigues-Lima, Fernando; Harris, Richard; Driscoll, Paul C; Abe, Koichiro; Fuchs, Helmut; de Angelis, Martin Hrabé; Yu, Philipp; Cho, Wohnwa; Katan, Matilda.

J Biol Chem ; 284(34): 23083-93, 2009 Aug 21.

Artigo em Inglês | MEDLINE | ID: mdl-19531496

15.

An EF hand mutation in Stim1 causes premature platelet activation and bleeding in mice.

Grosse, Johannes; Braun, Attila; Varga-Szabo, David; Beyersdorf, Niklas; Schneider, Boris; Zeitlmann, Lutz; Hanke, Petra; Schropp, Patricia; Mühlstedt, Silke; Zorn, Carolin; Huber, Michael; Schmittwolf, Carolin; Jagla, Wolfgang; Yu, Philipp; Kerkau, Thomas; Schulze, Harald; Nehls, Michael; Nieswandt, Bernhard.

J Clin Invest ; 117(11): 3540-50, 2007 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-17965774

16.

RNA-DNA hybrids and ssDNA differ in intracellular half-life and toll-like receptor 9 activation.

Obermann, Hannah-Lena; Eberhardt, Iris; Yu, Philipp; Kaufmann, Andreas; Bauer, Stefan.

Immunobiology ; 224(6): 843-851, 2019 11.

Artigo em Inglês | MEDLINE | ID: mdl-31521407

17.

Toll-like receptor 9 in murine lupus: more friend than foe!

Yu, Philipp; Musette, Philippe; Peng, Stanford L.

Immunobiology ; 213(2): 151-7, 2008.

Artigo em Inglês | MEDLINE | ID: mdl-18241699

18.

A splenic IgM memory subset with antibacterial specificities is sustained from persistent mucosal responses.

Le Gallou, Simon; Zhou, Zhicheng; Thai, Lan-Huong; Fritzen, Remi; de Los Aires, Alba Verge; Mégret, Jérôme; Yu, Philipp; Kitamura, Daisuke; Bille, Emmanuelle; Tros, Fabiola; Nassif, Xavier; Charbit, Alain; Weller, Sandra; Weill, Jean-Claude; Reynaud, Claude-Agnès.

J Exp Med ; 215(8): 2035-2053, 2018 08 06.

Artigo em Inglês | MEDLINE | ID: mdl-29959173

19.

Immunobiology of toll-like receptors in allergic disease.

Bauer, Stefan; Hangel, Doris; Yu, Philipp.

Immunobiology ; 212(6): 521-33, 2007.

Artigo em Inglês | MEDLINE | ID: mdl-17544836

20.

A Gain-Of-Function Mutation in the Plcg2 Gene Protects Mice from Helicobacter felis-Induced Gastric MALT Lymphoma.

Gossmann, Jennifer; Stolte, Manfred; Lohoff, Michael; Yu, Philipp; Moll, Roland; Finkernagel, Florian; Garn, Holger; Brendel, Cornelia; Bittner, Alwina; Neubauer, Andreas; Huynh, Minh Q.

PLoS One ; 11(3): e0150411, 2016.

Artigo em Inglês | MEDLINE | ID: mdl-26966907

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