Detalhe da pesquisa
1.
mRNA and gene editing: Late breaking therapies in liver diseases.
Hepatology
; 76(3): 869-887, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35243655
2.
AdrA as a Potential Immunomodulatory Candidate for STING-Mediated Antiviral Therapy That Required Both Type I IFN and TNF-α Production.
J Immunol
; 206(2): 376-385, 2021 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33298616
3.
Durable immunogenicity, adaptation to emerging variants, and low-dose efficacy of an AAV-based COVID-19 vaccine platform in macaques.
Mol Ther
; 30(9): 2952-2967, 2022 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35546782
4.
GPR108 Is a Highly Conserved AAV Entry Factor.
Mol Ther
; 28(2): 367-381, 2020 02 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31784416
5.
Successful Repeated Hepatic Gene Delivery in Mice and Non-human Primates Achieved by Sequential Administration of AAV5ch and AAV1.
Mol Ther
; 25(8): 1831-1842, 2017 08 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28596114
6.
Efficient and safe therapeutic use of paired Cas9-nickases for primary hyperoxaluria type 1.
EMBO Mol Med
; 16(1): 112-131, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38182795
7.
Gene therapy for liver diseases - progress and challenges.
Nat Rev Gastroenterol Hepatol
; 20(5): 288-305, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36646909
8.
Correlating physicochemical and biological properties to define critical quality attributes of a rAAV vaccine candidate.
Mol Ther Methods Clin Dev
; 30: 103-121, 2023 Sep 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37746246
9.
Efficient in vivo genome editing prevents hypertrophic cardiomyopathy in mice.
Nat Med
; 29(2): 412-421, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36797483
10.
Immunogenicity of an AAV-Based COVID-19 Vaccine in Murine Models of Obesity and Aging.
Viruses
; 14(4)2022 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35458550
11.
Computed tomography and [18F]-FDG PET imaging provide additional readouts for COVID-19 pathogenesis and therapies evaluation in non-human primates.
iScience
; 25(4): 104101, 2022 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35313622
12.
Ancestral library identifies conserved reprogrammable liver motif on AAV capsid.
Cell Rep Med
; 3(11): 100803, 2022 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36327973
13.
Novel vectors and approaches for gene therapy in liver diseases.
JHEP Rep
; 3(4): 100300, 2021 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-34159305
14.
An AAV-based, room-temperature-stable, single-dose COVID-19 vaccine provides durable immunogenicity and protection in non-human primates.
Cell Host Microbe
; 29(9): 1437-1453.e8, 2021 09 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34428428
15.
Immunogenicity of an AAV-based, room-temperature stable, single dose COVID-19 vaccine in mice and non-human primates.
bioRxiv
; 2021 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33442684
16.
Inhibition of MicroRNA 6937 Delays Photoreceptor and Vision Loss in a Mouse Model of Retinitis Pigmentosa.
Pharmaceutics
; 12(10)2020 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32987664
17.
In Vitro and In Vivo Genetic Disease Modeling via NHEJ-Precise Deletions Using CRISPR-Cas9.
Mol Ther Methods Clin Dev
; 19: 426-437, 2020 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33294491
18.
Genetic-Based Approaches to Inherited Metabolic Liver Diseases.
Hum Gene Ther
; 30(10): 1190-1203, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31347416
19.
Immunoadsorption enables successful rAAV5-mediated repeated hepatic gene delivery in nonhuman primates.
Blood Adv
; 3(17): 2632-2641, 2019 09 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31501158
20.
Tracing the fate of AAV vectors in the body.
Nat Biotechnol
; 2023 Nov 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38012451