RESUMO
In the title mol-ecule, C(21)H(18)N(2)S(2), the C=N-N angle of 117.6â (2)° is significantly smaller than the ideal value of 120° expected for sp(2)-hybridized N atoms. This is probably a consequence of repulsion between the nitro-gen lone pairs and the adjacent N atom, as suggested in Zheng, Qiu, Lin & Liu [Acta Cryst. (2006), E62, o1913-o1914]. The two neighbouring benzene rings form a dihedral angle of 75.95â (3)° with each other, while subtending dihedral angles of 84.18â (3) and 8.44â (2)° with the third ring in the structure.
RESUMO
In the title mol-ecule, C(15)H(12)ClN, the C=N and C=C bond lengths are 1.273â (2) and 1.324â (2)â Å, respectively. The two aromatic rings form a dihedral angle of 3.27â (3)°.
Assuntos
Antígeno de Maturação de Linfócitos B/imunologia , Resistencia a Medicamentos Antineoplásicos , Cadeias Pesadas de Imunoglobulinas/metabolismo , Imunoterapia Adotiva/métodos , Mieloma Múltiplo/terapia , Recidiva Local de Neoplasia/terapia , Anticorpos de Cadeia Única/metabolismo , Humanos , Cadeias Pesadas de Imunoglobulinas/genética , Mieloma Múltiplo/imunologia , Mieloma Múltiplo/patologia , Recidiva Local de Neoplasia/imunologia , Recidiva Local de Neoplasia/patologia , Indução de Remissão , Anticorpos de Cadeia Única/genéticaRESUMO
OBJECTIVE: To investigate the prevalence and distribution characteristics of Cyclospora cayetanensis and Cryptosporidium ssp. infection in diarrhea cases of Yunnan Province. METHODS: To collect fresh faeces from diarrhea cases in 7 counties/cities, examine the specimens by direct smear with iodine staining and modified acid-fast staining. RESULTS: The infection rate of C. cayetanensis and Cryptosporidium ssp. was 3.97% and 5.29%, respectively. The infection rate of the two pathogenic coccidians was as high as 10.64% and 8.51% in preschool children. C. cayetanensis was found in 3 counties and Cryptosporidium in 6 counties. CONCLUSION: Both C. cayetanensis and Cryptosporidium ssp. are prevalent in Yunnan Province with the latter distributed more widely, and the two pathogens are more prevalent in preschool children.