Detalhe da pesquisa
1.
Discovery of deaminase functions by structure-based protein clustering.
Cell
; 186(15): 3182-3195.e14, 2023 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37379837
2.
Off-target RNA mutation induced by DNA base editing and its elimination by mutagenesis.
Nature
; 571(7764): 275-278, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31181567
3.
FokI-RYdCas9 Mediates Nearly PAM-Less and High-Precise Gene Editing in Human Cells.
Curr Issues Mol Biol
; 46(5): 4021-4034, 2024 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38785516
4.
Programmable C-to-U RNA editing using the human APOBEC3A deaminase.
EMBO J
; 39(22): e104741, 2020 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33058229
5.
A rationally engineered cytosine base editor retains high on-target activity while reducing both DNA and RNA off-target effects.
Nat Methods
; 17(6): 600-604, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32424272
6.
Gene editing in a Myo6 semi-dominant mouse model rescues auditory function.
Mol Ther
; 30(1): 105-118, 2022 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34174443
7.
PHF7 is a novel histone H2A E3 ligase prior to histone-to-protamine exchange during spermiogenesis.
Development
; 146(13)2019 07 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31189663
8.
Programmable C-to-U RNA editing using the human APOBEC3A deaminase.
EMBO J
; 40(9): e108209, 2021 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33938012
9.
Anti-silencing factor 1A is associated with genome stability maintenance of mouse preimplantation embryos.
Biol Reprod
; 102(4): 817-827, 2020 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31916576
10.
Correction: PHF7 is a novel histone H2A E3 ligase prior to histone-to-protamine exchange during spermiogenesis.
Development
; 147(8)2020 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32341030
11.
ZPAC is required for normal spermatogenesis in mice.
Mol Reprod Dev
; 82(10): 747-55, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26153379
12.
Development of a universal antibiotic resistance screening system for efficient enrichment of C-to-G and A-to-G base editing.
Int J Biol Macromol
; 268(Pt 2): 131785, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38679258
13.
An ovalbumin fusion strategy to increase recombinant protein secretion in chicken eggs.
J Biol Eng
; 18(1): 5, 2024 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38212799
14.
Chromosome-level genome of Ambrosia trifida provides insights into adaptation and the evolution of pollen allergens.
Int J Biol Macromol
; 259(Pt 2): 129232, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38191104
15.
Undetectable off-target effects induced by FokI catalytic domain in mouse embryos.
Genome Biol
; 25(1): 51, 2024 Feb 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38378658
16.
Deep learning models incorporating endogenous factors beyond DNA sequences improve the prediction accuracy of base editing outcomes.
Cell Discov
; 10(1): 20, 2024 Feb 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38378648
17.
THEMIS is a substrate and allosteric activator of SHP1, playing dual roles during T cell development.
Nat Struct Mol Biol
; 31(1): 54-67, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38177672
18.
EpiCas-DL: Predicting sgRNA activity for CRISPR-mediated epigenome editing by deep learning.
Comput Struct Biotechnol J
; 21: 202-211, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36582444
19.
Treatment of autosomal dominant retinitis pigmentosa caused by RHO-P23H mutation with high-fidelity Cas13X in mice.
Mol Ther Nucleic Acids
; 33: 750-761, 2023 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37621413
20.
Genome-wide CRISPR off-target prediction and optimization using RNA-DNA interaction fingerprints.
Nat Commun
; 14(1): 7521, 2023 11 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37980345