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1.
Eur J Clin Pharmacol ; 69(4): 1025-9, 2013 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-23090698

RESUMO

PURPOSE: Continuation of coumarin therapy is important to prevent thromboembolic events. Continuation of medication, unrelated to the reason for hospital admission, may be at risk due to the patient's psychiatric status and the involvement of several physicians in patient care. METHODS: We performed a retrospective follow-up study of users of orally administered anticoagulants who were admitted to a psychiatric hospital. Information on patient characteristics, anticoagulant use, and International Normalized Ratio (INR) measurements was collected. Discontinuation of anticoagulant care was defined as no anticoagulant dispensing during the first 7 days of hospitalization and/or no INR measurement during hospitalization. Relative risks (RR) of discontinuation, overall and stratified by patient characteristics, was estimated using Cox regression analysis. RESULTS: Of 111 patients, 24.3 % had their anticoagulant care discontinued. For 17.1 %, no anticoagulant was dispensed during the first week, and 13.5 % had no INR measurement during hospitalization. CONCLUSIONS: Admission to a psychiatric hospital leads to discontinuation of anticoagulant care in 24.3 % of patients, with highest risk of discontinuation in patients admitted to nonpsychogeriatric wards. More research is needed to evaluate the clinical impact of this finding.


Assuntos
Anticoagulantes/administração & dosagem , Monitoramento de Medicamentos , Uso de Medicamentos/normas , Hospitalização , Hospitais Psiquiátricos , Anticoagulantes/uso terapêutico , Monitoramento de Medicamentos/métodos , Monitoramento de Medicamentos/normas , Seguimentos , Humanos , Coeficiente Internacional Normatizado , Transtornos Mentais/sangue , Transtornos Mentais/tratamento farmacológico , Qualidade da Assistência à Saúde , Estudos Retrospectivos
2.
Ned Tijdschr Geneeskd ; 141(5): 225-7, 1997 Feb 01.
Artigo em Holandês | MEDLINE | ID: mdl-9064537

RESUMO

In three men, aged 20, 42 and 32 years who suffered from excessive concern with an imaginary physical deviation, body dysmorphic disorder was diagnosed. By co-operation between treating psychiatrist and plastic surgeon the obsession, shame and avoidance behaviour could be alleviated.


Assuntos
Imagem Corporal , Transtorno Obsessivo-Compulsivo/psicologia , Transtornos Fóbicos/psicologia , Adulto , Humanos , Masculino , Transtorno Obsessivo-Compulsivo/terapia , Transtornos Fóbicos/terapia , Psicoterapia/métodos , Psicotrópicos/uso terapêutico
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