Pesquisa | BVS Violência e Saúde

1.

Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system.

Zetsche, Bernd; Gootenberg, Jonathan S; Abudayyeh, Omar O; Slaymaker, Ian M; Makarova, Kira S; Essletzbichler, Patrick; Volz, Sara E; Joung, Julia; van der Oost, John; Regev, Aviv; Koonin, Eugene V; Zhang, Feng.

Cell ; 163(3): 759-71, 2015 Oct 22.

Artigo em Inglês | MEDLINE | ID: mdl-26422227

2.

Compact but mighty: Biology and applications of type III-E CRISPR-Cas systems.

Steens, Jurre A; van der Oost, John; Staals, Raymond H J.

Mol Cell ; 82(23): 4405-4406, 2022 12 01.

Artigo em Inglês | MEDLINE | ID: mdl-36459983

3.

The miniature CRISPR-Cas12m effector binds DNA to block transcription.

Wu, Wen Y; Mohanraju, Prarthana; Liao, Chunyu; Adiego-Pérez, Belén; Creutzburg, Sjoerd C A; Makarova, Kira S; Keessen, Karlijn; Lindeboom, Timon A; Khan, Tahseen S; Prinsen, Stijn; Joosten, Rob; Yan, Winston X; Migur, Anzhela; Laffeber, Charlie; Scott, David A; Lebbink, Joyce H G; Koonin, Eugene V; Beisel, Chase L; van der Oost, John.

Mol Cell ; 82(23): 4487-4502.e7, 2022 12 01.

Artigo em Inglês | MEDLINE | ID: mdl-36427491

4.

Cryo-EM structure of the transposon-associated TnpB enzyme.

Nakagawa, Ryoya; Hirano, Hisato; Omura, Satoshi N; Nety, Suchita; Kannan, Soumya; Altae-Tran, Han; Yao, Xiao; Sakaguchi, Yuriko; Ohira, Takayuki; Wu, Wen Y; Nakayama, Hiroshi; Shuto, Yutaro; Tanaka, Tatsuki; Sano, Fumiya K; Kusakizako, Tsukasa; Kise, Yoshiaki; Itoh, Yuzuru; Dohmae, Naoshi; van der Oost, John; Suzuki, Tsutomu; Zhang, Feng; Nureki, Osamu.

Nature ; 616(7956): 390-397, 2023 04.

Artigo em Inglês | MEDLINE | ID: mdl-37020030

5.

The Ongoing Quest to Crack the Genetic Code for Protein Production.

Nieuwkoop, Thijs; Finger-Bou, Max; van der Oost, John; Claassens, Nico J.

Mol Cell ; 80(2): 193-209, 2020 10 15.

Artigo em Inglês | MEDLINE | ID: mdl-33010203

6.

Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a.

Swarts, Daan C; van der Oost, John; Jinek, Martin.

Mol Cell ; 66(2): 221-233.e4, 2017 Apr 20.

Artigo em Inglês | MEDLINE | ID: mdl-28431230

7.

Autonomous Generation and Loading of DNA Guides by Bacterial Argonaute.

Swarts, Daan C; Szczepaniak, Malwina; Sheng, Gang; Chandradoss, Stanley D; Zhu, Yifan; Timmers, Elizabeth M; Zhang, Yong; Zhao, Hongtu; Lou, Jizhong; Wang, Yanli; Joo, Chirlmin; van der Oost, John.

Mol Cell ; 65(6): 985-998.e6, 2017 Mar 16.

Artigo em Inglês | MEDLINE | ID: mdl-28262506

8.

Revealing determinants of translation efficiency via whole-gene codon randomization and machine learning.

Nieuwkoop, Thijs; Terlouw, Barbara R; Stevens, Katherine G; Scheltema, Richard A; de Ridder, Dick; van der Oost, John; Claassens, Nico J.

Nucleic Acids Res ; 51(5): 2363-2376, 2023 03 21.

Artigo em Inglês | MEDLINE | ID: mdl-36718935

9.

RNAi: prokaryotes get in on the act.

van der Oost, John; Brouns, Stan J J.

Cell ; 139(5): 863-5, 2009 Nov 25.

Artigo em Inglês | MEDLINE | ID: mdl-19945373

10.

Enhancement of CRISPR/Cas12a trans-cleavage activity using hairpin DNA reporters.

Rossetti, Marianna; Merlo, Rosa; Bagheri, Neda; Moscone, Danila; Valenti, Anna; Saha, Aakash; Arantes, Pablo R; Ippodrino, Rudy; Ricci, Francesco; Treglia, Ida; Delibato, Elisabetta; van der Oost, John; Palermo, Giulia; Perugino, Giuseppe; Porchetta, Alessandro.

Nucleic Acids Res ; 50(14): 8377-8391, 2022 08 12.

Artigo em Inglês | MEDLINE | ID: mdl-35822842

11.

Codon Bias as a Means to Fine-Tune Gene Expression.

Quax, Tessa E F; Claassens, Nico J; Söll, Dieter; van der Oost, John.

Mol Cell ; 59(2): 149-61, 2015 Jul 16.

Artigo em Inglês | MEDLINE | ID: mdl-26186290

12.

Streamlined CRISPR genome engineering in wild-type bacteria using SIBR-Cas.

Patinios, Constantinos; Creutzburg, Sjoerd C A; Arifah, Adini Q; Adiego-Pérez, Belén; Gyimah, Evans A; Ingham, Colin J; Kengen, Servé W M; van der Oost, John; Staals, Raymond H J.

Nucleic Acids Res ; 49(19): 11392-11404, 2021 11 08.

Artigo em Inglês | MEDLINE | ID: mdl-34614191

13.

Metabolic engineering of Clostridium autoethanogenum for ethyl acetate production from CO.

Dykstra, James C; van Oort, Jelle; Yazdi, Ali Tafazoli; Vossen, Eric; Patinios, Constantinos; van der Oost, John; Sousa, Diana Z; Kengen, Servé W M.

Microb Cell Fact ; 21(1): 243, 2022 Nov 23.

Artigo em Inglês | MEDLINE | ID: mdl-36419165

14.

Waive CRISPR patents to meet food needs in low-income countries.

van der Oost, John; Fresco, Louise O.

Nature ; 597(7875): 178, 2021 09.

Artigo em Inglês | MEDLINE | ID: mdl-34489579

15.

RNA targeting by the type III-A CRISPR-Cas Csm complex of Thermus thermophilus.

Staals, Raymond H J; Zhu, Yifan; Taylor, David W; Kornfeld, Jack E; Sharma, Kundan; Barendregt, Arjan; Koehorst, Jasper J; Vlot, Marnix; Neupane, Nirajan; Varossieau, Koen; Sakamoto, Keiko; Suzuki, Takehiro; Dohmae, Naoshi; Yokoyama, Shigeyuki; Schaap, Peter J; Urlaub, Henning; Heck, Albert J R; Nogales, Eva; Doudna, Jennifer A; Shinkai, Akeo; van der Oost, John.

Mol Cell ; 56(4): 518-30, 2014 Nov 20.

Artigo em Inglês | MEDLINE | ID: mdl-25457165

16.

Good guide, bad guide: spacer sequence-dependent cleavage efficiency of Cas12a.

Creutzburg, Sjoerd C A; Wu, Wen Y; Mohanraju, Prarthana; Swartjes, Thomas; Alkan, Ferhat; Gorodkin, Jan; Staals, Raymond H J; van der Oost, John.

Nucleic Acids Res ; 48(6): 3228-3243, 2020 04 06.

Artigo em Inglês | MEDLINE | ID: mdl-31989168

17.

Highly specific enrichment of rare nucleic acid fractions using Thermus thermophilus argonaute with applications in cancer diagnostics.

Song, Jinzhao; Hegge, Jorrit W; Mauk, Michael G; Chen, Junman; Till, Jacob E; Bhagwat, Neha; Azink, Lotte T; Peng, Jing; Sen, Moen; Mays, Jazmine; Carpenter, Erica L; van der Oost, John; Bau, Haim H.

Nucleic Acids Res ; 48(4): e19, 2020 02 28.

Artigo em Inglês | MEDLINE | ID: mdl-31828328

18.

High-throughput insertional mutagenesis reveals novel targets for enhancing lipid accumulation in Nannochloropsis oceanica.

Südfeld, Christian; Hubácek, Michal; Figueiredo, Daniel; Naduthodi, Mihris I S; van der Oost, John; Wijffels, René H; Barbosa, Maria J; D'Adamo, Sarah.

Metab Eng ; 66: 239-258, 2021 07.

Artigo em Inglês | MEDLINE | ID: mdl-33971293

19.

Medium-throughput in vitro detection of DNA cleavage by CRISPR-Cas12a.

Creutzburg, Sjoerd C A; Swartjes, Thomas; van der Oost, John.

Methods ; 172: 27-31, 2020 02 01.

Artigo em Inglês | MEDLINE | ID: mdl-31726224

20.

Adaptation and application of a two-plasmid inducible CRISPR-Cas9 system in Clostridium beijerinckii.

Diallo, Mamou; Hocq, Rémi; Collas, Florent; Chartier, Gwladys; Wasels, François; Wijaya, Hani Surya; Werten, Marc W T; Wolbert, Emil J H; Kengen, Servé W M; van der Oost, John; Ferreira, Nicolas Lopes; López-Contreras, Ana M.

Methods ; 172: 51-60, 2020 02 01.

Artigo em Inglês | MEDLINE | ID: mdl-31362039

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