Detalhe da pesquisa
1.
Unraveling the mystery of ocular retinoid turnover: Insights from albino mice and the role of STRA6.
J Biol Chem
; 300(3): 105781, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38395306
2.
Genetic tuning of ß-carotene oxygenase-1 activity rescues cone photoreceptor function in STRA6-deficient mice.
Hum Mol Genet
; 32(5): 798-809, 2023 02 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36150025
3.
Aster proteins mediate carotenoid transport in mammalian cells.
Proc Natl Acad Sci U S A
; 119(15): e2200068119, 2022 04 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35394870
4.
The vitamin A transporter STRA6 adjusts the stoichiometry of chromophore and opsins in visual pigment synthesis and recycling.
Hum Mol Genet
; 31(4): 548-560, 2022 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34508587
5.
Aster la vista: Unraveling the biochemical basis of carotenoid homeostasis in the human retina.
Bioessays
; 44(11): e2200133, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36127289
6.
ASTER-B regulates mitochondrial carotenoid transport and homeostasis.
J Lipid Res
; 64(5): 100369, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37030626
7.
Structural basis for carotenoid cleavage by an archaeal carotenoid dioxygenase.
Proc Natl Acad Sci U S A
; 117(33): 19914-19925, 2020 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32747548
8.
ß-Cryptoxanthin Attenuates Cigarette-Smoke-Induced Lung Lesions in the Absence of Carotenoid Cleavage Enzymes (BCO1/BCO2) in Mice.
Molecules
; 28(3)2023 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36771049
9.
Genetic dissection in mice reveals a dynamic crosstalk between the delivery pathways of vitamin A.
J Lipid Res
; 63(6): 100215, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35452666
10.
LRAT coordinates the negative-feedback regulation of intestinal retinoid biosynthesis from ß-carotene.
J Lipid Res
; 62: 100055, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33631212
11.
The human mitochondrial enzyme BCO2 exhibits catalytic activity toward carotenoids and apocarotenoids.
J Biol Chem
; 295(46): 15553-15565, 2020 11 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32873706
12.
ß-Carotene conversion to vitamin A delays atherosclerosis progression by decreasing hepatic lipid secretion in mice.
J Lipid Res
; 61(11): 1491-1503, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32963037
13.
Evidence for distinct rate-limiting steps in the cleavage of alkenes by carotenoid cleavage dioxygenases.
J Biol Chem
; 294(27): 10596-10606, 2019 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31138651
14.
Mutations in the Spliceosome Component CWC27 Cause Retinal Degeneration with or without Additional Developmental Anomalies.
Am J Hum Genet
; 100(4): 592-604, 2017 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28285769
15.
Overlapping Vitamin A Interventions with Provitamin A Carotenoids and Preformed Vitamin A Cause Excessive Liver Retinol Stores in Male Mongolian Gerbils.
J Nutr
; 150(11): 2912-2923, 2020 11 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32455433
16.
Astaxanthin-Shifted Gut Microbiota Is Associated with Inflammation and Metabolic Homeostasis in Mice.
J Nutr
; 150(10): 2687-2698, 2020 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32810865
17.
Transcription factor ISX mediates the cross talk between diet and immunity.
Proc Natl Acad Sci U S A
; 114(43): 11530-11535, 2017 10 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-29073082
18.
Protective role of carotenoids in the visual cycle.
FASEB J
; : fj201800467R, 2018 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29882710
19.
Preparation and characterization of metal-substituted carotenoid cleavage oxygenases.
J Biol Inorg Chem
; 23(6): 887-901, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29946976
20.
Structure and Spectroscopy of Alkene-Cleaving Dioxygenases Containing an Atypically Coordinated Non-Heme Iron Center.
Biochemistry
; 56(22): 2836-2852, 2017 06 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28493664