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J Anesth ; 37(4): 604-615, 2023 08.
Artigo em Inglês | MEDLINE | ID: mdl-37354352

RESUMO

BACKGROUND: The purpose of this study was to investigate the association between age and chronic postsurgical pain (CPSP) in patients who underwent elective surgery under general anesthesia, with a focus on long-term postsurgical analgesic use. To our knowledge, no previous study has examined this relationship in detail between older and younger patients. METHODS: We conducted a propensity score-matched (PSM) study to compare the rates of long-term (3 or 6 months) postoperative analgesic use between older adult (≥ 65 years) and younger (< 65 years) patients. Multivariate logistic regression was used to assess the use of analgesics as a surrogate indicator of CPSP. RESULTS: The PSM analysis included 62,784 surgical patients (31,392 in each group). Three months after surgery, the rates of analgesic use were significantly higher in the older age group (adjusted odds ratio [aOR], 1.45; 95% confidence interval [CI], 1.41-1.49) as well as for opioid use specifically (aOR, 1.34; 95% CI, 1.29-1.39). Six months after surgery, the rates of analgesic use remained higher in the older age group (aOR, 1.52; 95% CI, 1.47-1.58), and similarly for opioid use specifically (aOR, 1.42; 95% CI, 1.36-1.48). CONCLUSIONS: Our findings suggest that older adults have higher rates of long-term analgesic use for CPSP after elective surgery under general anesthesia. This study highlights the importance of addressing CPSP in older adult patients and considering age-related factors when managing postoperative pain.


Assuntos
Anestesia Geral , Dor Crônica , Dor Pós-Operatória , Idoso , Humanos , Analgésicos/uso terapêutico , Analgésicos Opioides/uso terapêutico , Anestesia Geral/efeitos adversos , Dor Crônica/tratamento farmacológico , Dor Crônica/epidemiologia , Dor Crônica/etiologia , Dor Pós-Operatória/tratamento farmacológico , Dor Pós-Operatória/epidemiologia , Dor Pós-Operatória/etiologia , Procedimentos Cirúrgicos Eletivos , Masculino , Feminino , Pessoa de Meia-Idade , Idoso de 80 Anos ou mais
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