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1.
Muscle Nerve ; 69(6): 691-698, 2024 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-38545741

RESUMO

INTRODUCTION/AIMS: Redundant nerve roots (RNRs) are abnormally elongated and tortuous nerve roots that develop secondary to degenerative spinal stenosis. RNRs have been associated with poorer clinical outcomes after decompression surgery; however, studies on their clinical characteristics are limited. This study aimed to investigate the association between RNRs and denervation potentials, that is, abnormal spontaneous activity (ASA), on electromyography. METHODS: We retrospectively reviewed data of patients who underwent an electrodiagnostic study of the lower extremities between January 2020 and March 2023. Of these, patients with lumbar central spinal stenosis, as seen on magnetic resonance imaging, were included. We analyzed clinical and imaging data, including presence of ASA, and compared them according to the presence of RNRs. Multivariable logistic regression analysis was employed to identify factors associated with development of ASA. RESULTS: Among the 2003 patients screened, 193 were included in the study. RNRs were associated with advanced age (p < .001), longer symptom duration (p = .009), smaller cross-sectional area of the dural sac at the stenotic level (p < .001), and higher frequency of ASA (p < .001). Higher probability of ASA was correlated with greater RNR severity (p < .001). In the multivariable logistic regression analysis, ASA occurrence was associated with smaller cross-sectional area, multiple stenotic sites, and severe-grade RNRs. DISCUSSION: The presence of RNRs, particularly severe-grade RNRs, was identified as a significant risk factor for the development of ASA on electromyography. This finding may aid physicians in estimating the prognosis of patients with central spinal stenosis.


Assuntos
Eletromiografia , Vértebras Lombares , Imageamento por Ressonância Magnética , Raízes Nervosas Espinhais , Estenose Espinal , Humanos , Estenose Espinal/diagnóstico por imagem , Estenose Espinal/cirurgia , Feminino , Masculino , Raízes Nervosas Espinhais/diagnóstico por imagem , Idoso , Pessoa de Meia-Idade , Estudos Retrospectivos , Vértebras Lombares/diagnóstico por imagem , Denervação/métodos , Idoso de 80 Anos ou mais
2.
Eur Spine J ; 33(9): 3443-3451, 2024 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-39017731

RESUMO

PURPOSE: Screwed anterior lumbar interbody fusion (SALIF) alleviates the need for supplemental posterior fixation leading to reduction of perioperative morbidity. Specifically, elderly and multimorbid patients would benefit from shorter operative time and faster recovery but tend to have low bone mineral density (BMD). The current study aimed to compare loosening, defined as increase of ROM and NZ, of SALIF versus transforaminal lumbar interbody fusion (TLIF) under cyclic loading in cadaveric spines with reduced BMD. METHODS: Twelve human spines (L4-S2; 6 male 6 female donors; age 70.6 ± 19.6; trabecular BMD of L5 84.2 ± 24.4 mgHA/cm3, range 51-119 mgHA/cm3) were assigned to two groups. SALIF or TLIF were instrumented at L5/S1. Range of motion (ROM) and neutral zone (NZ) were assessed before and after axial cyclic loading (0-1150 N, 2000 cycles, 0.5 Hz) in flexion-extension (Flex-Ext), lateral bending, (LB), axial rotation (AR). RESULTS: ROM of the SALIF specimens increased significantly in all loading directions (p ≤ 0.041), except for left AR (p = 0.053), whereas for TLIF it increased significantly in left LB (p = 0.033) and Flex (p = 0.015). NZ of SALIF showed increase in Flex-Ext and LB, whereas NZ of TLIF did not increase significantly in any motion direction. CONCLUSIONS: Axial compression loading caused loosening of SALIF in Flex-Ext and LB, but not TLIF at L5/S1 in low BMD specimens. Nevertheless, Post-cyclic ROM and NZ of SALIF is comparable to TLIF. This suggests that, neither construct is optimal for the use in patients with reduced BMD.


Assuntos
Densidade Óssea , Vértebras Lombares , Amplitude de Movimento Articular , Fusão Vertebral , Humanos , Feminino , Masculino , Vértebras Lombares/cirurgia , Vértebras Lombares/diagnóstico por imagem , Fusão Vertebral/métodos , Idoso , Densidade Óssea/fisiologia , Fenômenos Biomecânicos/fisiologia , Pessoa de Meia-Idade , Amplitude de Movimento Articular/fisiologia , Idoso de 80 Anos ou mais , Cadáver , Sacro/cirurgia , Sacro/diagnóstico por imagem , Sacro/fisiologia
3.
Eur Spine J ; 33(7): 2870-2877, 2024 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-38286907

RESUMO

PURPOSE: To report a unique case of incomplete CES following a rebar penetrating injury in perineal region with retro-pulsed fragment, which was treated with anterior approach and discuss suitable surgical approach. METHODS: Incomplete cauda equina syndrome caused by non-missile penetrating injury is extremely rare. A 26-year-old male patient presented incomplete cauda equina syndrome due to a penetrating rebar wound from his perineal region to the lumbosacral spine. Computed tomography demonstrated a bony fragment broken from S1 body compressing into the spinal canal. RESULTS: By anterior approach, we performed partial corpectomy of L5, decompression by retrieving the bony fragment and L5-S1 interbody fusion. The patient had a significant recovery, and no clinical complication was found after over 2-year follow-up. CONCLUSION: It is challenging to determine the optimal strategy of surgical treatment for penetrating spinal injuries with retained foreign bodies, here we suggest an anterior approach situation that has the advantage of being able to effectively perform decompression and prevent iatrogenic damages of thecal sac and nerve rootlets.


Assuntos
Síndrome da Cauda Equina , Vértebras Lombares , Ferimentos Perfurantes , Humanos , Masculino , Adulto , Síndrome da Cauda Equina/cirurgia , Síndrome da Cauda Equina/etiologia , Ferimentos Perfurantes/cirurgia , Ferimentos Perfurantes/complicações , Ferimentos Perfurantes/diagnóstico por imagem , Vértebras Lombares/cirurgia , Vértebras Lombares/lesões , Vértebras Lombares/diagnóstico por imagem , Descompressão Cirúrgica/métodos , Fusão Vertebral/métodos , Traumatismos da Coluna Vertebral/cirurgia , Traumatismos da Coluna Vertebral/complicações , Traumatismos da Coluna Vertebral/diagnóstico por imagem , Resultado do Tratamento , Ferimentos Penetrantes/cirurgia , Ferimentos Penetrantes/diagnóstico por imagem , Ferimentos Penetrantes/complicações
4.
Malays J Med Sci ; 30(2): 111-123, 2023 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-37102046

RESUMO

Background: This paper outlines a summary of examination techniques for the thoracic and lumbosacral spine. It starts with observation, palpation and a range of movements followed by various special tests to identify thoracic and lumbosacral spine pathology. Methods: Bedside instruments used include a measuring tape, scoliometer and back range of motion instrument (BROM II). Discussion: Back flexion-extension, lateral flexion and rotation were assessed with bedside instruments. This would aid in increasing the accuracy and precision of objective measurement while conducting a clinical examination to determine the back range motion. Specific tests were used to localise specific anatomical locations and identify the spine pathology that can help the clinician to diagnose and treat the disease.

5.
Artigo em Inglês, Russo | MEDLINE | ID: mdl-37011328

RESUMO

Currently, there is no information on the combined effect of body mass index (BMI), age, gender, main spinal-pelvic parameters and parameters of adjacent functional spinal unit (FSU) degeneration according to magnetic resonance imaging on development of adjacent segment degenerative disease (ASDd). OBJECTIVE: To evaluate the effect of preoperative biometric and instrumental parameters of adjacent FSU on the risk of ASDd after transforaminal lumbar interbody fusion and determine personalized neurosurgical approach. MATERIAL AND METHODS: We retrospectively studied patients after single-level transforaminal lumbar interbody fusion (group I, n=54), single-level transforaminal lumbar interbody fusion and interspinous stabilization of adjacent level (group II, n=55), preventive rigid fusion of adjacent segment (group III, n=56). Preoperative parameters and long-term clinical outcomes were assessed. RESULTS: Paired correlation analysis established the main predictors of ASDd. Regression analysis determined absolute values of these predictors for each type of surgical intervention. CONCLUSION: Surgical intervention at the level of asymptomatic proximal adjacent segment is recommended as interspinous stabilization for moderate degenerative lesions, BMI <25 kg/m2, difference between pelvic index and lumbar lordosis 10.5-15°, segmental lordosis 6.5-10.5°. In case of severe degenerative lesions, BMI 25.1-31.1 kg/m2, significant deviations of spinal-pelvic parameters (segmental lordosis 5.5-10.5°, difference between pelvic index and lumbar lordosis 15.2-20°), preventive rigid stabilization is indicated.


Assuntos
Lordose , Fusão Vertebral , Humanos , Lordose/diagnóstico por imagem , Lordose/cirurgia , Lordose/etiologia , Estudos Retrospectivos , Vértebras Lombares/diagnóstico por imagem , Vértebras Lombares/cirurgia , Fusão Vertebral/efeitos adversos , Fusão Vertebral/métodos , Fatores de Risco , Resultado do Tratamento
6.
Eur Spine J ; 31(1): 18-27, 2022 01.
Artigo em Inglês | MEDLINE | ID: mdl-34609616

RESUMO

PURPOSE: Surgical treatment of jumper's fractures is a highly demanding situation for the surgeon due to its rareness and frequent association with severe concomitant injuries. There is no current consensus regarding a standard treatment approach, thus reducing quality of care. Our objectives were to describe, apply and assess a novel surgical technic. METHODS: The presented research is an observational retrospective study of patients who underwent the described novel surgical intervention in a level 1 trauma center. We conducted analyses of the patient cohort using patient-related outcome measures at least 1 year after surgery, as well as investigating pain, quality of life and the clinical effectiveness of the procedure. RESULTS: A total of 24 patients (17 male and 7 female) with an average age 47 ± 16.3 years were included. ISS scores ranged from 9 to 66 with a mean ISS of 40 ± 15. Clinical scores exist of 15 out of 24 patients (62.5%). The mean VAS score was 53.7 ± 12.9. The mean EQ-5D index was 0.68 ± 0.22. Significant negative correlation existed between the ISS value and the EQ-5D index (r = - 0.704; p < 0.005) and EQ-5D VAS (r = - 0.809; p < 0.001). Anatomical reduction was achieved in all patients (n = 24). Radiological follow-up was performed in 58%. CONCLUSION: We present one of the largest studies with operatively treated jumper's fractures of the sacrum. The technique is capable of reproducibly restoring the physiological anatomy of the patient and allows pain-adapted mobilization.


Assuntos
Fraturas Ósseas , Sacro , Adulto , Feminino , Fixação Interna de Fraturas/métodos , Humanos , Masculino , Pessoa de Meia-Idade , Qualidade de Vida , Estudos Retrospectivos , Sacro/diagnóstico por imagem , Sacro/lesões , Sacro/cirurgia
7.
Korean J Parasitol ; 59(6): 635-638, 2021 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-34974670

RESUMO

In this study, we intended to describe a human case of lumbosacral canal sparganosis in People's Republic of China (China). A 56-year-old man was admitted to Xiangya Hospital Central South University in Changsha, Hunan province, China after having an experience of perianal pain for a week. An enhancing mass, a tumor clinically suggested, was showed at the S1-S2 level of the lumbosacral spine by the examination of magnetic resonance imaging (MRI) with gadolinium contrast. The patient was received the laminectomy from S1 to S2, and an ivory-white living worm was detected in inferior margin of L5. In ELISA-test with cerebrospinal fluid (CSF) and serum samples, anti-sparganum antibodies were detected. He had a ingesting history of undercooked frog meat in his youth. By the present study, a human case of spinal sparganosis invaded in lumbosacral canal at the S1-S2 level was diagnosed in China. Although the surgical removal of larvae is known to be the best way of treatment for sparganosis, we administered the high-dosage of praziquantel, albendazole and dexamethasone to prevent the occurrence of another remain worms in this study.


Assuntos
Esparganose , Adolescente , Animais , China , Humanos , Imageamento por Ressonância Magnética , Masculino , Pessoa de Meia-Idade , Praziquantel , Esparganose/diagnóstico por imagem , Esparganose/cirurgia , Plerocercoide
8.
Artigo em Russo | MEDLINE | ID: mdl-33560617

RESUMO

Smoking is an obvious risk factor of adverse events in early and long-term postoperative period after spine surgery including lumbar total disk arthroplasty. Objective. To study the effect of smoking on clinical and radiological outcomes after lumbar total disk arthroplasty. MATERIAL AND METHODS: A single-center retrospective observational cohort study was performed. We have analyzed medical records of patients who underwent single-level lumbar total disk arthroplasty for degenerative disease. RESULTS: The study included 57 medical records of respondents. The examined medical records were divided into two groups - smokers (n=26) and non-smokers (n=31). There were no significant between-group differences in clinical outcomes. Incidence of adverse events was similar too. Kaplan-Meier event-free survival was similar in both groups. There were no significant between-group differences in X-ray data. Development of heterotopic ossification after lumbar total disk arthroplasty was more active in smokers. CONCLUSION: Smoking has no significant effect on clinical and radiological outcomes in patients after single-level after lumbar total disk arthroplasty. On the other hand, smoking significantly increases formation of heterotopic ossification after lumbar total disk arthroplasty.


Assuntos
Degeneração do Disco Intervertebral , Ossificação Heterotópica , Substituição Total de Disco , Humanos , Degeneração do Disco Intervertebral/diagnóstico por imagem , Degeneração do Disco Intervertebral/etiologia , Degeneração do Disco Intervertebral/cirurgia , Ossificação Heterotópica/diagnóstico por imagem , Ossificação Heterotópica/epidemiologia , Ossificação Heterotópica/etiologia , Estudos Retrospectivos , Fatores de Risco , Fumar/efeitos adversos , Resultado do Tratamento
9.
Adv Exp Med Biol ; 1176: 47-52, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31054102

RESUMO

Low back pain (LBP) is a major health problem, particularly in the contemporary societies of highly developed countries. This study seeks to define the influence of basic demographic and social factors, such as gender, body mass, physical activity, and the type of work, on the occurrence of lumbosacral spine pain in the early and middle-late adulthood. The study was based on a self-reported survey, using the revised Oswestry Low Back Pain Disability Questionnaire to evaluate pain symptoms, and managing everyday tasks. Physical activity was evaluated on the Minnesota Leisure Time Physical Activity Questionnaire. We found that patients in the early adulthood had a significantly lower level of disability. The older patients had a greater low back pain and motion, sleeping, and social life problems. Neither did gender nor the type of work, leisure time physical activity, or body mass appreciably affect the level of disability due to low back pain in both younger and older patient groups. We conclude that, all else unchanged from the epidemiological standpoint, wear and tear of the spine structure naturally progressing with age seems a major determinant of the appearance of low back pain.


Assuntos
Pessoas com Deficiência , Dor Lombar , Adulto , Pessoas com Deficiência/estatística & dados numéricos , Exercício Físico , Feminino , Humanos , Dor Lombar/epidemiologia , Masculino , Atividade Motora , Fatores de Risco , Inquéritos e Questionários
10.
Artigo em Russo | MEDLINE | ID: mdl-31095127

RESUMO

THE RATIONALE: The differential approach taking into consideration the pathogenetic aspects of the pathological condition of interest with the identification of the principal cause of disorders in the musculo-skeletal system is a topical issue in the development of the measures for the rehabilitative treatment of the affected patients. Despite a great variety of methods and guidelines currently available for the conservative treatment of the musculoskeletal system diseases, further investigations and the development of the approaches and recommendations are needed for the correction and prevention of pathobiomechanical disorders and securing the optimal motor stereotype. AIM: The objective of the present study was to improve the existing methods for the correction of the lumbosacral orthosis in the patients presenting with patellofemoral pain syndrome with the use of physical exercise therapy for the improvement of their locomotor activity. MATERIAL AND METHODS: We have undertaken a randomized controlled clinical study involving 60 outpatients. They were divided into two groups designated as the main and control ones. The inclusion criteria were the age between 18 and 35 years, the feeling of discomfort or pain in the lumbosacral region, and the combined patellofemoral syndrome. All the patients underwent the comprehensive examination of the musculoskeletal system, and evaluation of pain intensity based on the relevant visual-analogue scales, stabilometry before and after the treatment of the patients comprising the main group with the use of the combined correction and of the control patients with the application of the conventional correction methods. RESULTS: The treatment with the use of the proposed original physical exercise therapy of the patients presenting with the pain syndrome in the lumbosacral region resulted in a reduction of its intensity by 27% on the average (p<0.05) and a significant 40% decrease in the frequency of dysfunction of the thoracoabdominal diaphragm. Simultaneously, the frequency of dysfunction of the muscles stabilizing the lumbosacral spine and the lower extremity on the side of the patellofemoral complex decreased by 53.4% and 17.8% on the average, respectively. Parameters of stabilometry evaluated from the results of the 'Mishen' (Target) test and the Romberg test with eyes closed improved by 1.9 times (p<0.05) and 2.5 times (p<0.05) on the average, respectively. CONCLUSION: The study has demonstrated that dysfunction of the sacral bone and muscles in the lumbosacral spine region responsible for the formation of the pain syndrome in the lower part of the back develops in 67% of the patients presenting with the patellofemoral pain syndrome. Physiotherapy including endurance-type exercises and activation of the muscles stabilizing the lumbosacral spine and lower extremities can improve results of rehabilitation.


Assuntos
Terapia por Exercício , Aparelhos Ortopédicos/efeitos adversos , Síndrome da Dor Patelofemoral/terapia , Adolescente , Adulto , Humanos , Região Lombossacral , Síndrome da Dor Patelofemoral/etiologia , Resultado do Tratamento , Adulto Jovem
11.
Eur Spine J ; 27(12): 3025-3033, 2018 12.
Artigo em Inglês | MEDLINE | ID: mdl-29110219

RESUMO

PURPOSE: U-shaped sacral fractures are extremely rare injuries that usually occur as a result of falls from considerable heights. Almost all treatment methods described to date aim solely at stabilizing the fracture but do not contribute to supporting the reduction of such fractures. Using existing implants the purpose of this study is to present a surgical technique that facilitates both the reduction and the stabilization of these injuries. The presented technique was evaluated in a series of three cases. METHODS: Polyaxial pedicle screws were placed through vertebral bodies L4 and L5. Two long pedicle screws were implanted in the posterior iliac spine. The lumbar pedicle screws were held with two longitudinal rods, and the pelvic screws with one transverse connecting rod. The lumbar longitudinal and pelvic transverse rods were connected via two hinge-like connecting elements. First, distraction was performed between lumbar pedicle screws L5 and the sacral transverse rod. Lordosis was then restored via the hinge joint, thereby eliminating kyphosis. After tightening all moving elements, the fracture was reduced and stabilized. RESULTS: Computed tomography documented anatomical reduction and fracture healing was achieved in all cases. Two of three patients could be fully mobilized immediately; mobilization of the third patient was delayed due to multiple injuries. Two patients showed neurological symptoms. In one case, complete remission was achieved within 3 weeks, while in the other patient a clear improvement was observed. In all cases, the implant was removed after 8-12 months. There were no post-operative complications, such as infections, wound-healing disorders, neurological deterioration, implant failure, or premature loosening. CONCLUSIONS: The surgical procedure was successful, since it considerably facilitated reduction, thereby shortening surgery time. The stabilization was sufficient to fully mobilize the patients. The procedure is based on existing implant components and is thus routinely available.


Assuntos
Fixação Interna de Fraturas/métodos , Ílio/cirurgia , Vértebras Lombares/cirurgia , Sacro/lesões , Fraturas da Coluna Vertebral/cirurgia , Acidentes por Quedas , Adulto , Idoso , Feminino , Fixação Interna de Fraturas/instrumentação , Consolidação da Fratura , Humanos , Cifose/cirurgia , Parafusos Pediculares , Ossos Pélvicos/cirurgia , Complicações Pós-Operatórias/cirurgia , Radiografia , Sacro/diagnóstico por imagem , Sacro/cirurgia , Fraturas da Coluna Vertebral/diagnóstico por imagem , Tomografia Computadorizada por Raios X
12.
Proc Natl Acad Sci U S A ; 112(26): 8064-9, 2015 Jun 30.
Artigo em Inglês | MEDLINE | ID: mdl-26077908

RESUMO

Spondylolysis is a fracture in part of the vertebra with a reported prevalence of about 3-6% in the general population. Genetic etiology of this disorder remains unknown. The present study was aimed at identifying genomic mutations in patients with dysplastic spondylolysis as well as the potential pathogenesis of the abnormalities. Whole-exome sequencing and functional analysis were performed for patients with spondylolysis. We identified a novel heterozygous mutation (c.2286A > T; p.D673V) in the sulfate transporter gene SLC26A2 in five affected subjects of a Chinese family. Two additional mutations (e.g., c.1922A > G; p.H641R and g.18654T > C in the intron 1) in the gene were identified by screening a cohort of 30 unrelated patients with the disease. In situ hybridization analysis showed that SLC26A2 is abundantly expressed in the lumbosacral spine of the mouse embryo at day 14.5. Sulfate uptake activities in CHO cells transfected with mutant SLC26A2 were dramatically reduced compared with the wild type, confirming the pathogenicity of the two missense mutations. Further analysis of the gene-disease network revealed a convergent pathogenic network for the development of lumbosacral spine. To our knowledge, our findings provide the first identification of autosomal dominant SLC26A2 mutations in patients with dysplastic spondylolysis, suggesting a new clinical entity in the pathogenesis of chondrodysplasia involving lumbosacral spine. The analysis of the gene-disease network may shed new light on the study of patients with dysplastic spondylolysis and spondylolisthesis as well as high-risk individuals who are asymptomatic.


Assuntos
Proteínas de Transporte de Ânions/genética , Mutação , Espondilólise/genética , Adulto , Idoso , Sequência de Aminoácidos , Animais , Proteínas de Transporte de Ânions/química , Feminino , Humanos , Hibridização In Situ , Masculino , Pessoa de Meia-Idade , Dados de Sequência Molecular , Linhagem , Homologia de Sequência de Aminoácidos , Espondilólise/fisiopatologia , Transportadores de Sulfato
13.
Adv Gerontol ; 30(5): 776-783, 2017.
Artigo em Russo | MEDLINE | ID: mdl-29322748

RESUMO

The aim of the study was a comparative analysis of the clinical and radiographic effectiveness of the use of interbody fusion and open pedicle screw stabilization of simultaneous and new minimally invasive techniques facet fixation system «Facet Wedge¼ in the treatment of degenerative diseases of the lumbar spine in elderly patients. The study included 39 elderly patients (older than 60), which carries out the transforaminal interbody fusion Cage «T-pal¼: open transpedicaular stabilization was used in 1st group (n=23), ipsilateral open transpedicular stabilization with contralateral transfaset installing titanium Cage «facet Wedge¼ -in 2nd group (n=16). We used intraoperative interventions and specific post-operative patient management, clinical data and radiographic outcomes for a comparative analysis of the parameters. Dynamic assessment was made in a period of 8 to 36 months after surgery (median 24 mo.). As a result, it found that the use of the system «facet Wedge¼ allows you to achieve the best clinical outcomes and fewer postoperative complications compared with open transpedicular stabilization in similar radiographic findings of bone block formation. Low traumatic facet fixation makes it possible to use methods for the treatment of elderly patients with degenerative diseases of the lumbosacral spine.


Assuntos
Vértebras Lombares/cirurgia , Parafusos Pediculares , Doenças da Coluna Vertebral/cirurgia , Fusão Vertebral/métodos , Idoso , Humanos , Vértebras Lombares/diagnóstico por imagem , Pessoa de Meia-Idade , Complicações Pós-Operatórias , Doenças da Coluna Vertebral/diagnóstico por imagem , Resultado do Tratamento
14.
J Anat ; 229(1): 82-91, 2016 07.
Artigo em Inglês | MEDLINE | ID: mdl-26916466

RESUMO

Previous work suggests females are evolutionarily adapted to have greater lumbar lordosis than males to aid in pregnancy load-bearing, but no consensus exists. To explore further sex-differences in the lumbar spine, and to understand contradictions in the literature, we conducted a cross-sectional retrospective study of sex-differences in lumbar spine morphology and sacral orientation. In addition, our sample includes data for separate standing and supine samples of males and females to examine potential sex-differences in postural loading on lumbosacral morphology. We measured sagittal lumbosacral morphology on 200 radiographs. Measurements include: lumbar angle (L1-S1), lumbar vertebral body and disc wedging angles, sacral slope and pelvic incidence. Lumbar angle, representative of lordotic curvature between L1 and S1, was 7.3° greater in females than males, when standing. There were no significant sex-differences in lumbar angle when supine. This difference in standing lumbar angle can be explained by greater lordotic wedging of the lumbar vertebrae (L1-L5) in females. Additionally, sacral slope was greater in females than males, when standing. There were no significant sex-differences in pelvic incidence. Our results support that females have greater lumbar lordosis than males when standing, but not when supine - suggesting a potentially greater range of motion in the female spine. Furthermore, sex-differences in the lumbar spine appear to be supported by postural differences in sacral-orientation and morphological differences in the vertebral body wedging. A better understanding of sex-differences in lumbosacral morphology may explain sex-differences in spinal conditions, as well as promote necessary sex-specific treatments.


Assuntos
Vértebras Lombares/anatomia & histologia , Caracteres Sexuais , Adolescente , Adulto , Estudos Transversais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Equilíbrio Postural , Estudos Retrospectivos , Adulto Jovem
15.
Eur Spine J ; 25(11): 3589-3595, 2016 11.
Artigo em Inglês | MEDLINE | ID: mdl-26538158

RESUMO

PURPOSE: Pelvic incidence is a position- and posture-independent parameter used to quantify sagittal balance of the spine, sacrum, pelvis and hips. Its functional consequences have been associated with a number of different pathologies of the spine. However, there exists considerable controversy over which demographic features contribute to the development of pelvic incidence. METHODS: 880 cadaveric skeletons from the Hamann-Todd Osteological Collection were obtained. The innominate bones and sacrum were reconstructed, and pelvic incidence was measured using a previously validated technique. Specimens with obvious fracture, infection, or rheumatologic conditions were excluded from study. Descriptive data of age at the time of death, gender, race and height were collected. RESULTS: The average pelvic incidence was 46.0° ± 11.0°. Pelvic incidence did not change with age (r = 0.026, p = 0.288). There was no difference in pelvic incidence measurements between females and males (47.2° ± 13.8° vs. 45.8° ± 10.4°, respectively; p = 0.257), although this analysis was under-powered. Pelvic incidence was higher in African-Americans compared to Caucasians (48.9° ± 11.0° vs. 44.9° ± 10.8°; p = 0.001). There was no association between height and pelvic incidence (r = -0.042, p = 0.164). CONCLUSIONS: This study represents the largest single cohort of pelvic incidence measurements reported in the literature. Our data suggest that pelvic incidence does not change with age or height, although racial differences do exist. As spine care providers increasingly rely on pelvic incidence as an important means to quantify sagittal balance, the normative data provided herein will provide an essential reference.


Assuntos
Pelve , Postura/fisiologia , Adolescente , Adulto , Negro ou Afro-Americano/estatística & dados numéricos , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Pelve/anatomia & histologia , Pelve/diagnóstico por imagem , Radiografia , População Branca/estatística & dados numéricos , Adulto Jovem
16.
Eur Spine J ; 25(3): 870-6, 2016 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-26342703

RESUMO

PURPOSE: The cortical bone trajectory (CBT) is a novel lumbar pedicle screw trajectory. The aim of this study was to conduct a detailed morphometric measurement of the lumbosacral spine for CBT pedicle screw, using the inferior facet of the cephalad level as a bony landmark. METHODS: The three-dimensional computed tomography (3D-CT) scans of 86 adults who underwent examination of the lumbosacral spine were studied. The distances from the starting point to the inferior, lateral and medial border of the inferior facet of the cephalad level were measured. The angles formed between the screw trajectory and the sagittal plane, the superior endplate of the vertebral body and the posterior margin of the pars interarticularis were defined as the transverse angle (TA), cephalad angle 1 (CA1) and cephalad angle 2 (CA2), respectively. RESULTS: The distances from the inferior border of inferior facet to the starting point from L1 to S1 were 8.9, 6.3, 4.1, 2.9, 1.4 and 0 mm, respectively. The distances from the medial border of the inferior facet to the starting point from L1 to S1 were between 3 and 4 mm. TA from L1 to S1 was 9.0°, 9.6°, 11.3°, 13.5°, 15.5°, and 8.2°, respectively. CA1/CA2 from L1 to S1 was 26.7°/38.7°, 26.0°/38.7°, 26.9°/38.0°, 24.4°/37.2°, 22.9°/35.1° and 18.4°/47.8°, respectively. The maximum screw diameters from L1 to S1 were 4.8, 5.1, 6.1, 6.8, 7.8, and 6.1 mm, respectively. Twenty-five millimeter can serve as a safe maximum length of CBT pedicle screws. CONCLUSIONS: The inferior facet of the cephalad level is an attractive bony landmark for establishing a starting point of CBT for minimally invasive spine surgery.


Assuntos
Vértebras Lombares/diagnóstico por imagem , Parafusos Pediculares , Sacro/diagnóstico por imagem , Fusão Vertebral/métodos , Adulto , Idoso , Idoso de 80 Anos ou mais , Pontos de Referência Anatômicos , Feminino , Humanos , Imageamento Tridimensional , Vértebras Lombares/cirurgia , Masculino , Pessoa de Meia-Idade , Procedimentos Cirúrgicos Minimamente Invasivos/métodos , Sacro/cirurgia , Tomografia Computadorizada por Raios X , Adulto Jovem , Articulação Zigapofisária/diagnóstico por imagem
17.
Eur Spine J ; 24(11): 2520-4, 2015 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-25366230

RESUMO

PURPOSE: The purpose was to investigate the median sacral artery (MSA) anatomical pathway in terms of its relationship to the lumbosacral spine. METHODS: The posterior wall and lumbosacral spine of 54 adult embalmed cadavers were dissected. The MSA emerging point was identified. The distance from its emerging point to the lateral border of the vertebral body was measured bilaterally. The pathway of the MSA from the emerging point to the sacral promontory was described together with the MSA length. All outcomes were independently measured by two observers. Statistics on obtained data were calculated. RESULTS: Most of the MSA emerging points were at the L5 vertebral body (94.4 %). The emerging point from the right and left lateral border of the L5 vertebral body was 3.31 ± 0.54 cm and 2.39 ± 0.51 cm, respectively. The MSA then lay along the middle one-third of the anterior surface of the lumbosacral junction. The mean length between the emerging point and the sacral promontory was 2.73 ± 0.97 cm. CONCLUSIONS: The MSA anatomy is important for prevention of intra-operative bleeding. For anterior lumbosacral surgery, the MSA should be identified and controlled before proceeding with the spinal surgery. For posterior bicortical sacral screw placement, the screw tip should be fluoroscopically checked to avoid inserting the screw tip into the mid sacral promontory. By first approaching the anterior sacral promontory, the surgeon will find the MSA within the middle one-third zone, and 2.47-2.99 cm cephalad to this, the iliac vessels. Knowledge of the MSA helps the surgeon to operate more safely.


Assuntos
Aorta Abdominal/anatomia & histologia , Vértebras Lombares/cirurgia , Sacro/irrigação sanguínea , Adulto , Idoso , Idoso de 80 Anos ou mais , Cadáver , Feminino , Humanos , Região Lombossacral/cirurgia , Masculino , Pessoa de Meia-Idade , Pelve/cirurgia , Sacro/cirurgia
18.
Orthop Res Rev ; 16: 35-42, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38292458

RESUMO

Purpose: The main objective of this study was to provide a description and classification of lumbosacral spine injuries based on the new AOSpine classification system. Methods: A cross-sectional study was conducted on 75 patients with lumbosacral spine trauma who were admitted to Hue University of Medicine and Pharmacy Hospital in Hue, Vietnam, between April 2021 and July 2022. All patients underwent lumbosacral computed tomography, and each injured vertebra was classified according to the AOSpine classification system. The frequency and percentage of subtypes of lumbosacral spine trauma were determined. Results: The mean age of the patients was 50.6 ± 16.1 years, and the male-to-female ratio was 1.5:1. Falls and traffic accidents were found to be the main causes of injuries. Among the patients, 78.7% did not exhibit any neurological symptoms, while 1.3% experienced complete hemiplegia and 20% had incomplete hemiplegia. The most common fracture subtype was A3, accounting for 34.6% of cases. Conclusion: This study provides valuable insights into the demographics, associated injuries, and classification of traumatic lumbosacral spine injuries based on the new AOSpine classification system. The study found that falls and motor vehicle accidents were the main causes of these injuries, with a higher proportion of male patients. The majority of injuries were classified as type A fractures, while type C fractures were the least common. Sacral fractures were relatively infrequent and often associated with pelvic ring fractures. These findings contribute to our understanding of lumbosacral spine trauma and can aid in the development of more effective treatment protocols.

19.
World Neurosurg ; 2024 Sep 07.
Artigo em Inglês | MEDLINE | ID: mdl-39182832

RESUMO

BACKGROUND: The relationship of spinopelvic parameters with spondylolisthesis is widely explored. However, there is scarce evidence on correlation of tuberculosis of lumbar spine with respect to spinopelvic harmony. The current study aims to find the association between functional outcomes and spinopelvic parameters in lumbar spine tuberculosis treatment. METHODS: A total of 47 patients with active tuberculosis confined to lumbar spine were prospectively analyzed and divided into 2 groups according to mode of intervention. Group A included 26 operatively managed patients and group B had 21 conservatively managed cases. Functional parameters comprising Oswestry Disability Index (ODI) and Visual Analog Scale (VAS) along with spinopelvic radiologic parameters (pelvic incidence [PI], pelvic tilt [PT], sacral slope [SS], lumbar lordosis [LL], PI-LL, sagittal vertical axis) in both groups were analyzed at 0 and 6 months of follow-up. RESULTS: Both the groups showed significant improvement from initial presentation to final follow-up in ODI (Group A: 85.4 ± 12.1-12.3 ± 3.2, P = 0.02; Group B: 82.5 ± 10.06-36.8 ± 11.9, P = 0.04) and VAS (Group A: 8.1 ± 1.2-1.4 ± 0.9, P = 0.02; Group B: 8.5 ± 0.09-3.5 ± 1.1, P = 0.02). Statistically significant (P < 0.05) difference was observed in both functional outcome parameters between the 2 groups at 2-month and 6-month follow-up, compared with nonsignificant difference (P > 0.05) at presentation. Better improvements of spinopelvic parameters of PT, SS, LL, PI-LL were observed in Group A and in both groups the difference of these parameters correlated with differences of functional outcome parameters, though PI showed no correlation. CONCLUSIONS: The spinopelvic parameters played significant role in functional outcome. There is better functional outcome when LL is adequately restored. Surgical correction offered betterment of spinopelvic parameters like PT, SS, an sagittal vertical axis, which in turn leads to improvement in functional outcome.

20.
Cureus ; 16(9): e68436, 2024 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-39360075

RESUMO

Conjoined nerve roots (CNRs) are an uncommon condition often overlooked until surgery, posing significant intraoperative risks. This case report discusses a 21-year-old male diagnosed incidentally with a left lumbosacral CNR involving the fifth lumbar (L5) and first sacral (S1) spinal nerve roots following a work-related back injury, emphasizing the importance of preoperative imaging. Accurate early diagnosis of CNRs can prevent surgical complications and guide appropriate management, highlighting the need for careful preoperative planning and patient education.

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