HIV Testing and Treatment among HIV-Positive Men who have Sex with Men (MSM) Living in Russia: Data from Two Waves of the European MSM Internet Survey.

We examined changes in HIV testing and medical care among men who have sex with men (MSM) in Russia. Data come from the 2010 and 2017 waves of the European MSM Internet Survey. From 2010 to 2017 there was an increase in the proportion who had ever received an HIV test (+ 11.2%), had tested for HIV in the last year (+ 2.1%), had ever taken antiretroviral therapy (ART) (+ 31.9), were currently taking ART (+ 31.5%), and had an undetectable viral load (+ 19.4%). These results are encouraging, yet they also reveal that substantial proportions of MSM experience considerable unmet prevention and treatment needs.

RESUMEN: Examinamos los cambios en las pruebas de detección de VIH y la atención médica entre hombres que tienen sexo con hombres (HSH) en Rusia. Los datos provienen de las olas de 2010 y 2017 de la Encuesta Europea de Internet para HSH. De 2010 a 2017 hubo un aumento en la proporción de quienes alguna vez se habían hecho una prueba de VIH (+ 11.2%), se habían hecho una prueba de VIH en el último año (+ 2.1%), alguna vez habían tomado terapia antirretroviral (TAR) (+ 31.9%), estaban tomando TAR actualmente (+ 31.5%) y tenían una carga viral indetectable (+ 19.4%). Estos resultados son alentadores, pero también revelan que una proporción sustancial de HSH experimenta considerables necesidades de prevención y tratamiento no satisfechas.

Non-beverage alcohol consumption in Russia: new evidence from Jewish Autonomous Oblast.

INTRODUCTION: Previous studies in Izhevsk, Novosibirsk, and Kazan have found that non-beverage alcohol is a large part of alcohol consumption in Russia. Whereas those places are relatively high-income cities, there are no studies about such a problem in low-income regions of Russia. The aim of this study is to investigate correlates and factors associated with non-beverage alcohol consumption in eastern regions of Russia, e.g. the Jewish Autonomous Oblast and to assess effectiveness of implementing Russian policies to restrict consumption of non-beverage alcohol. MATERIALS AND METHODS: A survey of adults in the Jewish Autonomous Oblast of Russia was performed on workdays to assess non-beverage drinking patterns in summer 2022. The questionnaire included questions about socio-demographic status and alcohol use, including non-beverage alcohol consumption and drinking patterns. We use logistic regression to identify risk factors of consuming non-beverages. RESULTS: First, ~30% of individuals suffering from alcohol problems drink non-beverage alcohol. Second, those who regularly consume non-beverage alcohol compared with those who chronically drink legal strong alcohol are on average more likely to experience the negative effects of alcohol consumption. Third, income and marriage are the main factors negatively associated with surrogate alcohol consumption. Besides, age shows a curvilinear relationship with that. CONCLUSIONS: We suggest that a modified anti-surrogate policy to increase the minimum price of pharmacy alcohol and to enforce restrictions on the sale of non-beverage alcohol is needed in Russia. Such measures could prevent an increase in non-beverage alcohol consumption in Russia against the backdrop of declining real incomes of the population.

Validity and reliability of the Russian version of the revised Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS-R).

OBJECTIVE: The aim of this study is to elaborate a valid and reliable Russian version of the ALSFRS-R. METHODS: Russian adaptation of the ALSFRS-R was applied twice in 50 ALS patients followed by the test-retest analysis with a 7-day interval between applications and internal consistency analysis. RESULTS: Test-retest analysis showed very strong correlation for all of the ALSFRS-R variables. The intra-class correlation coefficient was 0.83. CONCLUSION: The elaborated Russian version of the ALSFRS-R has shown to be comparable with the original English version of the scale.

Exploring audiovisual speech perception in monolingual and bilingual children in Uzbekistan.

This study aimed to investigate the development of audiovisual speech perception in monolingual Uzbek-speaking and bilingual Uzbek-Russian-speaking children, focusing on the impact of language experience on audiovisual speech perception and the role of visual phonetic (i.e., mouth movements corresponding to phonetic/lexical information) and temporal (i.e., timing of speech signals) cues. A total of 321 children aged 4 to 10 years in Tashkent, Uzbekistan, discriminated /ba/ and /da/ syllables across three conditions: auditory-only, audiovisual phonetic (i.e., sound accompanied by mouth movements), and audiovisual temporal (i.e., sound onset/offset accompanied by mouth opening/closing). Effects of modality (audiovisual phonetic, audiovisual temporal, or audio-only cues), age, group (monolingual or bilingual), and their interactions were tested using a Bayesian regression model. Overall, older participants performed better than younger participants. Participants performed better in the audiovisual phonetic modality compared with the auditory modality. However, no significant difference between monolingual and bilingual children was observed across all modalities. This finding stands in contrast to earlier studies. We attribute the contrasting findings of our study and the existing literature to the cross-linguistic similarity of the language pairs involved. When the languages spoken by bilinguals exhibit substantial linguistic similarity, there may be an increased necessity to disambiguate speech signals, leading to a greater reliance on audiovisual cues. The limited phonological similarity between Uzbek and Russian might have minimized bilinguals' need to rely on visual speech cues, contributing to the lack of group differences in our study.

Attention-language interface in Multilingual Assessment instrument for Narratives.

The current study employed the Multilingual Assessment Instrument for Narratives (MAIN) to test comprehension of narrative macrostructure in Russian in a visual world eye-tracking paradigm. The four MAIN visual narratives are structurally similar and question referents' goals and internal states (IS). Previous research revealed that children's MAIN comprehension differed among the four narratives in German, Swedish, Russian, and Turkish, but it is not clear why. We tested whether the difference in comprehension was (a) present, (b) caused by complicated inferences in understanding IS compared with goals, and (c) ameliorated by orienting visual attention to the referents whose IS was critical for accurate comprehension. Our findings confirmed (a) and (b) but found no effect of attentional cues on accuracy for (c). The multidimensional theory of narrative organization of children's knowledge of macrostructure needs to consider the type of inferences necessary for IS that are influenced by subjective interpretation and reasoning.

Mental Health and well-being During the COVID-19 Pandemic and After the Russian Invasion of Ukraine.

The study compared the mental health of university students during the COVID-19 pandemic and the Russian invasion of Ukraine. A repeated online cross-sectional study was performed twice among university students in Ukraine: in November 2020 (Pre-war sample, n = 752) and September-October 2022 (During-war sample, n = 862). The survey measured life satisfaction (SWLS), perceived stress (PSS-10), anxiety (GAD-7), and depression (PHQ-9). Stress, anxiety, and life satisfaction levels were similar during the war and pandemic, while symptoms of depression decreased during the war, compared to the pandemic. Network analysis showed that anxiety has a crucial effect on depression and stress, and stress is most closely related to life satisfaction. The association of life satisfaction with anxiety and depression disappeared in wartime, in contrast to the pandemic. The priority of prevention and intervention programs in wartime Ukraine should focus on anxiety as the most influential factor in other mental health and well-being problems. The results showed high resistance and adaptation to war conditions among university students in Ukraine.

The first study of the prevalence and genetic diversity of Theileria equi and Babesia caballi in horses in Russia.

Equine piroplasmosis (EP) is a global worldwide infection, which can lead to the death of animals. Despite the causative agents of EP being well studied, there are no data on the distribution and genetic characteristics of EP agents in any region of Russia. In this study, blood samples from 750 horses from Novosibirsk province, Irkutsk province, and Altai region of Russian Siberia were examined for the presence of EP agents. Theileria equi and Babesia caballi were detected in all examined regions, with mean prevalence rates of 60.4% and 7.2%, respectively. The identified pathogens were genetically characterized by the 18S rRNA gene. The determined T. equi sequences were highly conserved and belonged to genotypes A and E, with genotype E being found in 88.6% of genotyped samples. In contrast to T. equi, B. caballi sequences were genetically diverse. Seven sequence variants of B. caballi were identified, and only two of them matched known sequences from the GenBank database. The determined B. caballi sequences belonged to four distinct branches within genotype A. Mixed infections with several variants of B. caballi or with T. equi and B. caballi were common. The conducted phylogenetic analysis based on all available B. caballi sequences of the 18S rRNA gene (> 900 bp) from GenBank and from this study first demonstrated the presence of five monophyletic clusters within genotype A and three clusters within genotype B. Thus, the genetic study of B. caballi from Siberia has significantly expanded the data on the genetic diversity of this pathogen.

Evaluation of marketing authorization and labels of medicines in 2021 WHO Model List of Essential Medicines for Children in China, the Russian Federation and Brazil.

OBJECTIVE: This work compares the marketing authorization, labels and dosage forms of medicines in the WHO Model List of Essential Medicines for Children (EMLc) in China, the Russian Federation and Brazil to urge policymakers to pay more attention to paediatric medication. METHODS: Medicines were selected from the 8th EMLc. By searching relevant databases, which include different types of medical information in China, the Russian Federation and Brazil, the marketing authorization, labels and dosage forms of paediatric medicines in the three countries were evaluated. RESULTS: A total of 485 drug products containing 312 active pharmaceutical ingredients listed in the WHO EMLc were evaluated. Among them, 344 products were approved for use in China, 286 in the Russian Federation and 264 in Brazil. Out of the 344 approved medicines, 317 (92.15%) were authorized for paediatric use in China, 224 (78.32%) in the Russian Federation and 218 (82.58%) in Brazil. In terms of guidance information labelling on drug labels, 75.08%, 83.04% and 88.07% of paediatric drugs approved in China, the Russian Federation and Brazil, respectively, clearly indicated the usage and dosage for paediatric use. Additionally, injections and tablets were the most prevalent dosage forms in these three countries. CONCLUSION: There is still scope for enhancing the marketing authorization and development of dosage forms for paediatric medicines in the three countries. Furthermore, additional measures are being implemented to enhance the information provided on drug labels for children, particularly in China.

Interactions at the Oviposition Scar: Molecular and Metabolic Insights into Elaeagnus angustifolia's Resistance Response to Anoplophora glabripennis.

The Russian olive (Elaeagnus angustifolia), which functions as a "dead-end trap tree" for the Asian long-horned beetle (Anoplophora glabripennis) in mixed plantations, can successfully attract Asian long-horned beetles for oviposition and subsequently kill the eggs by gum. This study aimed to investigate gum secretion differences by comparing molecular and metabolic features across three conditions-an oviposition scar, a mechanical scar, and a healthy branch-using high-performance liquid chromatography and high-throughput RNA sequencing methods. Our findings indicated that the gum mass secreted by an oviposition scar was 1.65 times greater than that secreted by a mechanical scar. Significant differences in gene expression and metabolism were observed among the three comparison groups. A Kyoto Encyclopedia of Genes and Genomes annotation and enrichment analysis showed that an oviposition scar significantly affected starch and sucrose metabolism, leading to the discovery of 52 differentially expressed genes and 7 differentially accumulated metabolites. A network interaction analysis of differentially expressed metabolites and genes showed that EaSUS1, EaYfcE1, and EaPGM1 regulate sucrose, uridine diphosphate glucose, α-D-glucose-1P, and D-glucose-6P. Although the polysaccharide content in the OSs was 2.22 times higher than that in the MSs, the sucrose content was lower. The results indicated that the Asian long-horned beetle causes Russian olive sucrose degradation and D-glucose-6P formation. Therefore, we hypothesized that damage caused by the Asian long-horned beetle could enhance tree gum secretions through hydrolyzed sucrose and stimulate the Russian olive's specific immune response. Our study focused on the first pair of a dead-end trap tree and an invasive borer pest in forestry, potentially offering valuable insights into the ecological self-regulation of Asian long-horned beetle outbreaks.

The impact of economic development of primary and secondary industries on national CO2 emissions: The case of Russian regions.

In today's world, where economic development and environmental sustainability are becoming increasingly important aspects of national strategy, attention to the impact of different economic sectors on climate change is becoming an integral part of scientific research. This article focuses on analyzing the impact of primary and secondary economic sectors development on carbon dioxide (CO2) emissions at the sub-national level in Russia from 2005 to 2019. The aim of the study is to provide an in-depth understanding of the relationships between the dynamics of these sectors and CO2 emission levels in different regions of the country. Weighted regression and panel data methods were applied to better identify the patterns of the impact. The results show that the size of population and electricity consumption have the highest impact on CO2 emissions. So that, the expansion of nuclear and gas generation capacity, as well as significant improvement of energy efficiency, are of crucial importance to reduce the emissions. Other sectors have a heterogeneous impact and requires more differential approaches, considering the specifics of regions. Taking into account the significant differences between the Russian constituent entities, this paper emphasizes the low informativeness of assessments at the national level and their inadequacy in terms of improving the efficiency of domestic management, including decarbonization policies.

Global energy transition and foreign environmental regulations: Impacts on Russian regions' export volumes.

This paper analyses the impacts of trading partners' environmental regulation on the export volumes of the Russian regions, using panel data covering about 140,000 observations in 84 Russian regions and 204 countries for the period 2013-2020. We employ the Gravity Model of international trade and Heckman Sample Selection methodology, with the fixed effects and random effects Poisson Pseudo-Maximum Likelihood techniques to analyse two subsamples of the Russian regions with different shares of environmentally sensitive goods in regional exports. As a robustness check, we utilize the non-parametric Driscoll-Kraay approach. The results of the econometric estimation demonstrate that environmental regulations enhance the export of regions with a high share of environmentally sensitive goods in export structure, while for the rest of the regions the environmental regulations negatively affect export volumes. The promoting effect is associated with a higher level of innovativeness of the regions and the role of the global energy transition process. We conclude that the environmental agenda is a challenge for some Russian regional exporters due to the lack of own environmental regulation, and to the specific features of the commodity and geographic structure of exports. To transform the negative impact into the positive one for all Russian regions, policy measures are necessary on the federal, regional, and company levels, encompassing environmental regulations and green development strategies, along with innovation and cluster policies, and the development of human capital and infrastructure.

Parafoveal letter identification in Russian: Confusion matrices based on error rates.

In the present study, we introduce parafoveal letter confusion matrices for the Russian language, which uses the Cyrillic script. To ensure that our confusion rates reflect parafoveal processing and no other effects, we employed an adapted boundary paradigm (Rayner, 1975) that prevented the participants from directly fixating the letter stimuli. Additionally, we assessed confusability under isolated and word-like (crowded) conditions using two modern fonts, since previous research showed that letter recognition depended on crowding and font (Coates, 2015; Pelli et al., 2006). Our additional goal was to gain insight into what letter features or configurational patterns might be essential for letter recognition in Russian; thus, we conducted exploratory clustering analysis on visual confusion scores to identify groups of similar letters. To support this analysis, we conducted a comprehensive review of over 20 studies that proposed crucial properties of Latin letters relevant to character perception. The summary of this review is valuable not only for our current study but also for future research in the field.

Linguistic disfluencies in Russian-speaking typically and atypically developing children: individual variability in different contexts.

Disfluency in children and adults seems to occur like errors of speech but, at the same time, is an essential feature of spontaneous (unprepared) speech. The present study aimed to evaluate linguistic disfluencies in typically and atypically developing Russian-speaking children from the perspective of the dynamic adaptive model of self-monitoring in speech production. The study collected four language samples from 10 six-year-old children with developmental language disorder and 14 typically developing peers: two storytelling tasks, structured conversation, and a play argument. After transcribing audio-recordings and marking linguistic disfluencies, the authors conducted structured distributional analysis. The distribution of several indexes of disfluency was estimated to assess the prevalence and profiles of different (sub)types of disfluencies. The disfluency rate statistics were similar between the typically developing children and children with developmental language disorder. The distributional indexes score showed that tasks significantly impacted the rate of different (sub)types of disfluencies. Task-related patterns in a set of the distributional indexes significantly distinguished the groups. Thus, changes in the disfluency profile related to different external factors, as a sign of a flexibility of an adaptive self-monitoring system, may be limited in children with developmental language disorder.

Characteristics of the mental health of employees of healthcare facilities in the conditions of war.

OBJECTIVE: Aim: To study the state of mental health of staff of healthcare facilities (HCFs) of different categories (managers, doctors, nurses) 2 years after the beginning of the Russian invasion of Ukraine. PATIENTS AND METHODS: Materials and Methods: The study, using valid psycho-diagnostic methods, was conducted in 3 stages: studying the frequency of mental states, Mental Health Continuum, and occupational self-efficacy. Using descriptive and analytical statistics, we analyzed the results obtained from 114 respondents. RESULTS: Results: It was found that in the majority of the study group, regardless of the position held (manager, doctor, nurse), the levels of anxiety, frustration, aggressiveness, and rigidity were low (64.0%-50.9% of respondents); flourishing and high development of occupational self-efficacy were recorded in 59.6% and 61.0%, staff of HCFs respectively. A small proportion of specialists (10.5%-4.4%) revealed a high level of manifestation of mental states; languishing and a low level of professional self-efficacy were practically absent. In other study participants, all indicators were at the borderline level. CONCLUSION: Conclusions: Almost 2 years of functioning in the context of the war has led to the development of a certain adaptation and resilience in all categories of healthcare employees, which allows them to fulfill their professional duties. At the same time, there is a significant number of healthcare professionals who have moderate and high levels of mental stress, and problems with mental health stability, which requires systemic decisions to be made at the sectoral level to ensure the mental health of staff of healthcare facilities.

Superconscious processes as mental images of a higher order (in the context of telezombification).

OBJECTIVE: Aim: The paper aims to examine superconscious processes as mental images of a higher order in the context of telezombification. PATIENTS AND METHODS: Materials and Methods: The authors used interpretive research paradigm, psychoanalysis, basic principles of hermeneutics, phenomenological approach along with general scientific methods, such as induction, deduction, generalization, etc. CONCLUSION: Conclusions: With the beginning of the russian full-scale attack on Ukraine, russian atrocities in Bucha, Mariupol and other cities and villages of the country, many Ukrainian citizens asked about what has happened to the russian society, the state authorities, who set the goal of destroying Ukraine as a state and all its inhabitants as a nation. Then Ukrainians have labelled the invaders and the authorities of Russia as non-humans. And this is a fair name for them. The fact is that these occupiers and their neo-Nazi leaders have a destroyed, distorted consciousness as a result of which they became incapable of realizing their thought processes. The consciousness of such persons gradually degrades towards animal thinking, the so-called proto-thinking. This is one direction to not realizing one's intentions and actions at the level of both subconscious and partially conscious analysis of primary mental images (images of a first and second orders). The second direction is the role of superconscious processes, in particular mental images of a higher level, which also form the worldview positions of an individual in the process of viewing and listening to certain information, while remaining, at the same time, unconscious until a certain time. Together, these directions form a person's attitude to existing social and worldview problems.

1,3,5-2,4,6-Functionalized Benzene Molecular Cage: An Environmentally Responsive Scaffold that Supports Hierarchical Superstructures.

New stimulus-responsive scaffolds are of interest as constituents of hierarchical supramolecular ensembles. 1,3,5-2,4,6-Functionalized, facially segregated benzene moieties have a time-honored role as building blocks for host molecules. However, their user as switchable motifs in the construction of multi-component supramolecular structures remains poorly explored. Here, we report a molecular cage 1, which consists of a bent anthracene dimer 3 paired with 1,3,5-tris(aminomethyl)-2,4,6-triethylbenzene 2. As the result of the pH-induced ababab↔bababa isomerization of the constituent-functionalized benzene units derived from 2, this cage can reversibly convert between an open state and a closed form, both in solution and in the solid state. Cage 1 was used to create stimuli-responsive hierarchical superstructures, namely Russian doll-like complexes with [K⊂18-crown-6⊂1]+ and [K⊂cryptand-222⊂1]+. The reversible assembly and disassembly of these superstructures could be induced by switching cage 1 from its open to closed form. The present study thus provides an unusual example where pH-triggered conformation motion within a cage-like scaffold is used to control the formation and disassociation of hierarchical ensembles.

Russia Weaponization of Canada's Far Right and Far Left to Undermine Support for Ukraine.

This article details the Russian government's efforts to influence Canadians' perceptions of the war in Ukraine. Specifically, we examined Russian information campaigns tailored to Canadian audiences on X (formerly known as Twitter) and the supportive ecosystems of accounts that amplify those campaigns. By 2023, this ecosystem included at least 200,000 X accounts that have shared content with millions of Canadians. We identified ninety accounts with an outsized influence. The vast majority of the influential Canadian accounts were far right or far left in orientation. These networks were among Canada's most prolific and influential political communities online. We determined this by comparing these networks' potential influence to the online community engaging with Canada's 338 members of Parliament on X and a sample of twenty influential X accounts in Canada. The sophistication and proliferation of Canada-tailored narratives suggest a highly organized and well-funded effort to target Canadian support for Ukraine.

[The metamorphoses of denationalization of 1993. Report-I. The market fight for medications import].

In the history of the Russian pharmaceutical market the year of 1993 became the year of formation of rules of market relations and changing under them of market landscape. The significant segment of state-centralized purchases moved under responsibility of regional authorities and their health care authorities. At that, powers of three former state organizations being occupied with purchases of imported medications were distributed between new state companies of Ministry of Health and commercial organizations and firms that entered pharmaceutical market. This diversity rather soon gave rise to competitive fight for budget funds and experiments of Government with market regulation. The traces of these clashes and attempts to make market regulated can be found in Ministry of Health archives and journal publications. The Report I reveals circumstances of entrance of Ministry of Health into market relationships and its acquisition of market player identity.

[Russian Medical Academy of Continuing Professional Education - the leading educational institution in the country for the training of forensic medical personnel (for the 90th anniversary from the establishment of the department of forensic medicine)]. / Rossiiskaya meditsinskaya akademiya nepreryvnogo professional'nogo obrazovaniya ­ vedushchee obrazovatel'noe uchrezhdenie strany po podgotovke sudebno-meditsinskikh kadrov (k 90-letiyu so dnya obrazovaniya kafedry sudebnoi meditsiny).

The article presents a detailed analysis of the stages of formation, development and achievements of the forensic medicine department of the Russian Medical Academy of Continuing Professional Education of the Ministry of Health of the Russian Federation, established in 1933 yr. More than 100 resident doctors and 15 PhD students have been trained in the department for 90 years. As a part of additional professional education implementation, more than 800 cycles of training courses for forensic medical and forensic experts and more than 30 cycles of professional retraining for doctors of other specialties have been carried out. More than 160 thous. specialists have been trained at the department since its establishment. Many employees of the department were directly involved in the performance of the most complicated and socially significant forensic medical examinations. The article describes the main achievements and scientific directions of the department's staff activity, directions and prospects of improving the training of forensic medical personnel in the country.

[To assess Resilience of Russian cities under international sanctions and the consequences of COVID-19: a sociological study].

The paper presents the results of in-depth interviews and a questionnaire survey of the Russian cites administration representatives about cities resilience under the sanctions pressure and COVID-19. The survey was conducted by the Center for Territorial Changes and Urban Development of IPEI RANEPA in March-May 2023, it was attended by representatives of the administration of more than 50 cities of the Russian Federation. We found overall situation as stable: social programs are being implemented in full, unemployment is decreasing, construction of municipal facilities continues, problems with failures in the supply of spare parts, equipment and components are being solved. At the same time, the sanctions have affected the urban economy in completely different ways: while in some cities show significant negative effect, in others the impact of sanctions is insignificant. Cites face number of new challenges: disruption of supply chains, refusal to supply paid equipment, inability to find analogues of imported equipment with the necessary characteristics, rising prices for spare parts. components and construction materials, the rupture of established sales channels to unfriendly countries, a drop in municipal budget revenues, etc. The heads of the city administration work overtime to solve emerging problems, organize interaction between enterprises, establish and deepen business contacts with friendly countries, put forward proposals to improve the situation at the federal level. New tasks successfully solved, although it requires serious efforts. To respond to new challenges, we need a new, more decentralized and local-oriented style of public administration, a process of well-established feedback.