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Nutrients ; 13(3)2021 Mar 23.
Artigo em Inglês | MEDLINE | ID: mdl-33806781

RESUMO

Whey protein hydrolysates (WPHs) are one of the most promising sources of biofunctional peptides with such beneficial properties as antioxidant, antihypertensive, anti-inflammatory and others. WPHs also could be used as foaming agents for aerated products (e.g., milk shake type drinks). However, WPH alone has a bitter taste and foamed WPH should be stabilized by additional ingredients. Here, we present a composition including WPH and three polysaccharides-pumpkin pectin, sodium alginate and ι-carrageenan-used as foam stabilizers. Polysaccharide content was selected according to foaming, organoleptic antioxidant and angiotensin-I-converting enzyme inhibitory characteristics of the resulted composition. Further, the hypotensive, antioxidant and hepatoprotective properties of the composition were proved by in vivo tests performed in spontaneously hypertensive rats and Wistar rats with CCl4-induced hepatic injury.


Assuntos
Hipotensão/dietoterapia , Polissacarídeos/farmacologia , Proteínas do Soro do Leite/metabolismo , Alginatos , Inibidores da Enzima Conversora de Angiotensina/farmacologia , Animais , Anti-Inflamatórios/farmacologia , Anti-Hipertensivos/farmacologia , Antioxidantes/farmacologia , Cucurbita , Carboidratos da Dieta , Modelos Animais de Doenças , Masculino , Estresse Oxidativo/efeitos dos fármacos , Pectinas , Peptídeos , Peptidil Dipeptidase A , Hidrolisados de Proteína , Ratos , Ratos Wistar
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