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1.
J Med Virol ; 96(2): e29431, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-38293752

RESUMO

The aim of the study was to determine the presence of human papillomavirus (HPV) in patients with intractable plantar keratosis (IPK) by comparing the histopathological findings of biopsies. A prospective, observational, and concordance study was carried out. Three different specimens were taken from each IPK. A first punch was sent for histopathological examination, and a second punch and a superficial skin scraping were both sent for HPV  polymerase chain reaction (PCR) and type determination. A total of 51 patients were included. From the histopathological examination, it was determined that 35 (68.6%) samples were diagnosed as warts and 16 (31.3%) as keratosis. However, the presence of HPV was confirmed by PCR in 49 (96.1%) and in 42 (82.4%) samples obtained by punch and superficial scraping, respectively. In the 49 PCR-positive samples, the most common HPV types were HPV1, HPV2, HPV27, HPV57, and HPV65, accounting for 81.6% of the samples. In conclusion, this study demonstrates that HPV infection and IPK lesions are very closely related. Although we cannot confirm that HPV is the cause of the development of IPK, the high prevalence of HPV observed in these lesions calls for a change to the procedures for managing IPK.


Assuntos
Ceratose , Infecções por Papillomavirus , Verrugas , Humanos , Infecções por Papillomavirus/complicações , Infecções por Papillomavirus/epidemiologia , Papillomavirus Humano , Estudos Prospectivos , Verrugas/epidemiologia , Papillomaviridae/genética , DNA Viral/genética , DNA Viral/análise
2.
Skeletal Radiol ; 51(6): 1143-1151, 2022 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-34704114

RESUMO

Hallux pain is a common entity with a differential diagnoses including hallux valgus, hallux limitus/rigidus, and gout and specifically at the interphalangeal joint (IPJ), flexor hallucis longus (FHL) tenosynovitis, and joint arthrosis. An under-recognized source of pain is the os interphalangeus, an ossicle typically located at the plantar aspect of the hallucal interphalangeal joint. This ossicle is radiographically visible in its ossified form in 2-13% of individuals, but can also be present as an ossified or non-ossified nodule in patients. The os interphalangeus may be centrally or eccentrically located, and although originally believed to be a sesamoid bone in the FHL tendon, it is an ossicle located in the joint capsule of the IPJ and separated from the tendon by a bursa. When the ossicle is absent, the bursa is also absent and the tendon is attached to the joint capsule. Infrequently, the os may be located eccentrically under the first IPJ and reflect persistence of one of the distal phalanx. Rarely, the os interphalangeus may be dorsal to the IPJ. The os interphalangeus is best evaluated on radiographs, ultrasound, and MRI. Pain is a result of altered mechanics with arthrosis or frictional effects with bursitis, tenosynovitis, or intractable plantar keratosis (IPK). The ossicle may also displace into a dislocated IPJ, preventing reduction. The os interphalangeus may be centrally or eccentrically located, and although originally believed to be a sesamoid bone. This has been found within the plantar joint capsule of the distal hallucal interphalangeal joint and separated from the tendon by a bursa. Uncommonly, the location may be plantar eccentric and reflect persistence of one of the ossification centers of the distal phalanx. Although the ossicle can be imaged with standard AP and lateral radiographs in many cases, in those cases of unexplained pain with no radiographically visible ossicle, and the presence of friction blisters, intractable plantar keratosis (IPK), hyper-extension of the IPJ, hallux limitus/rigidus, or metatarsophalangeal joint (MTPJ) arthrodesis, an MRI or CT should be considered to identify a non-ossified fibrocartilaginous node. This is of particular concern in a patient with a history of underling diabetes mellitus or other metabolic disorders associated with diminished pedal sensation where neurotrophic changes place them most at risk for complications associated with excessive plantar pressure. Pain is a result of altered biomechanics with arthrosis, or frictional effects causing bursitis, tenosynovitis, or IPK. The ossicle may also displace into a dislocated IPJ, preventing reduction. In this article, we will describe the anatomy and imaging appearance of the common os interphalangeus variants and associated complications including frictional effects, arthrosis, and IPK and discuss conservative and surgical management of a symptomatic ossicle.


Assuntos
Bursite , Doenças do Pé , Hallux Limitus , Hallux , Artropatias , Luxações Articulares , Ceratose , Articulação Metatarsofalângica , Osteoartrite , Tenossinovite , Hallux/diagnóstico por imagem , Humanos , Articulação Metatarsofalângica/diagnóstico por imagem , Articulação Metatarsofalângica/cirurgia , Morbidade , Dor
3.
J Foot Ankle Surg ; 61(1): 175-180, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-34266722

RESUMO

In this retrospective case series, we aimed to study arthroscopic sesamoidectomy, including surgical methods, clinical outcomes, and complications. We retrospectively reviewed the medical records of patients with hallux sesamoid disorders who underwent arthroscopic sesamoidectomy from July 2015 to July 2017. The visual analog scale for rating pain, Japanese Society for Surgery of the Foot scale scores, number of days taken to return to normal daily living, number of months taken to return to playing sports, and complications were analyzed. The mean follow-up duration was 3.2 years. Among 14 patients, there were 8 females and 6 males (median age: 39 years). The mean visual analog scale score improved from 75.4 to 14.3 mm; the mean Japanese Society for Surgery of the Foot score improved from 55.2 to 88.0 points. The mean time to return to activities of daily living was 5.3 days. Among the 5 patients who played sports, 3 and 2 patients resumed playing sports at 3 and 12 postoperative months, respectively. Complications included wound pain (n = 4), discomfort in severe weather (n = 4), numbness (n = 3), pain in the sole other than in the ball of the foot (n = 2), pain during hallux dorsiflexion (n = 2), residual sesamoid discomfort (n = 1), swelling (n = 1), toe-in gait (n = 1), and metatarsal head bone marrow edema (n = 1). Despite good clinical outcomes of arthroscopic sesamoidectomy, patients should be made aware of the many potential complications of this procedure prior to surgery.


Assuntos
Hallux Valgus , Hallux , Articulação Metatarsofalângica , Procedimentos Ortopédicos , Ossos Sesamoides , Atividades Cotidianas , Adulto , Feminino , Hallux/cirurgia , Hallux Valgus/cirurgia , Humanos , Masculino , Estudos Retrospectivos , Ossos Sesamoides/diagnóstico por imagem , Ossos Sesamoides/cirurgia
4.
Foot (Edinb) ; 34: 23-27, 2018 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-29202430

RESUMO

AIM: The purpose of this study was to evaluate the treatment of plantar skin lesions by excision and rotation skin flap closure with reference to patient satisfaction; patient reported outcomes and complication rates. METHOD: A retrospective audit of 54 consecutive patients who had undergone plantar lesion excision with rotation skin flap between May 2011 and November 2015 under the care of experienced consultant podiatric surgeons. A total of 36 patients were included in this study, 16 were lost to follow up, 2 patients were excluded due to non-related pathology. Outcomes were reviewed retrospectively via data extracted from PASCOM-10. This included the MOXFQ and also the PSQ-10 patient satisfaction questionnaire. Data extracted was analysed. RESULTS: The mean MOXFQ scores improved across the three domains. Walking/standing improved from 68.75 (SD: 17.62) pre-operative to 41.38 (SD: 32.94) post-operative. Pain improved from 63.47 (SD: 19.41) pre-operative to 36.53 (SD: 25.51) post-operative and social interaction improved from 53.88 (SD: 20.33) pre-operative to 29.13 (SD: 26.56) post-operative. Similarly, the PSQ-10 scores have shown positive outcomes where 88.9% out of the cohort felt that their aims of surgery had been met. CONCLUSION: This audit has demonstrated that the Schrudde flap is an effective and alternative safe surgical procedure for the treatment of intractable plantar keratosis and viral warts.


Assuntos
Doenças do Pé/cirurgia , Ceratose/cirurgia , Satisfação do Paciente/estatística & dados numéricos , Placa Plantar/cirurgia , Retalhos Cirúrgicos/transplante , Adulto , Idoso , Feminino , Doenças do Pé/diagnóstico , Sobrevivência de Enxerto , Humanos , Ceratose/diagnóstico , Masculino , Auditoria Médica , Pessoa de Meia-Idade , Placa Plantar/fisiopatologia , Estudos Retrospectivos , Medição de Risco , Índice de Gravidade de Doença , Resultado do Tratamento , Reino Unido , Cicatrização/fisiologia
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