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Arh Hig Rada Toksikol ; 73(4): 256-259, 2022 Dec 01.
Artigo em Inglês | MEDLINE | ID: mdl-36607724

RESUMO

Cardiopulmonary bypass (CPB) is an essential technique in cardiac surgery but is also associated with adverse effects, including the systemic inflammatory response syndrome that manifests itself as ischaemia-reperfusion injury and multi-organ dysfunction. The aim of this mini review is to take a look at the current knowledge of resveratrol, a stilbenoid and natural antioxidant believed to have many cardioprotective effects including vasodilation, lowering of blood pressure and reactive oxygen species levels, suppression of low-density lipoprotein peroxidation, and mitigation of ischaemia/-reperfusion injury. We mostly focus on its cardioprotective potential in patients undergoing cardiac surgery supported by CPB. Current findings, however, are still inconclusive and call for further research, including clinical trials.


Assuntos
Antioxidantes , Procedimentos Cirúrgicos Cardíacos , Humanos , Antioxidantes/uso terapêutico , Resveratrol/uso terapêutico , Procedimentos Cirúrgicos Cardíacos/efeitos adversos , Ponte Cardiopulmonar/efeitos adversos , Ponte Cardiopulmonar/métodos , Espécies Reativas de Oxigênio
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