Reduced glutathione accelerates the oxidative damage produced by sodium n-propylthiosulfate, one of the causative agents of onion-induced hemolytic anemia in dogs.

Yamato, O; Hayashi, M; Kasai, E; Tajima, M; Yamasaki, M; Maede, Y

Yamato, O; Hayashi, M; Kasai, E; Tajima, M; Yamasaki, M; Maede, Y.

Affiliation

Yamato O; Laboratory of Internal Medicine, Department of Veterinary Clinical Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo 060-0818, Japan.

Biochim Biophys Acta ; 1427(2): 175-82, 1999 Apr 19.

Article in En | MEDLINE | ID: mdl-10216234

Subject(s)

Erythrocytes/drug effects; Glutathione/deficiency; Onions/toxicity; Oxidants/toxicity; Thiosulfates/toxicity; Anemia, Hemolytic/chemically induced; Animals; Cells, Cultured; Dinitrochlorobenzene/pharmacology; Dogs; Erythrocytes/metabolism; Glutathione/blood; Methemoglobin/analysis; Onions/chemistry; Oxidative Stress; Potassium/blood; Thiosulfates/analysis

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Collection: 01-internacional Database: MEDLINE Main subject: Thiosulfates / Oxidants / Onions / Erythrocytes / Glutathione Limits: Animals Language: En Journal: Biochim Biophys Acta Year: 1999 Type: Article Affiliation country: Japan

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