Glucose metabolism and insulin sensitivity in transgenic mice overexpressing leptin with lethal yellow agouti mutation: usefulness of leptin for the treatment of obesity-associated diabetes.

Masuzaki, H; Ogawa, Y; Aizawa-Abe, M; Hosoda, K; Suga, J; Ebihara, K; Satoh, N; Iwai, H; Inoue, G; Nishimura, H; Yoshimasa, Y; Nakao, K

Masuzaki, H; Ogawa, Y; Aizawa-Abe, M; Hosoda, K; Suga, J; Ebihara, K; Satoh, N; Iwai, H; Inoue, G; Nishimura, H; Yoshimasa, Y; Nakao, K.

Affiliation

Masuzaki H; Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Japan.

Diabetes ; 48(8): 1615-22, 1999 Aug.

Article in En | MEDLINE | ID: mdl-10426381

Subject(s)

Diabetes Mellitus/metabolism; Glucose/metabolism; Insulin/physiology; Mutation/physiology; Obesity; Proteins/metabolism; Aging/physiology; Animals; Body Weight/physiology; Diabetes Mellitus/genetics; Diabetes Mellitus/physiopathology; Eating/physiology; Female; Food Deprivation/physiology; Leptin; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains/genetics; Mice, Transgenic/genetics; Proteins/therapeutic use

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Collection: 01-internacional Database: MEDLINE Main subject: Proteins / Diabetes Mellitus / Glucose / Insulin / Mutation / Obesity Type of study: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: Diabetes Year: 1999 Type: Article Affiliation country: Japan

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