Diltiazem enhances the analgesic but not the respiratory depressant effects of morphine in rhesus monkeys.

Kishioka, S; Ko, M C; Woods, J H

Kishioka, S; Ko, M C; Woods, J H.

Affiliation

Kishioka S; Department of Pharmacology, The University of Michigan, Ann Arbor, MI 48109, USA.

Eur J Pharmacol ; 397(1): 85-92, 2000 May 26.

Article in En | MEDLINE | ID: mdl-10844102

Subject(s)

Analgesics, Opioid/pharmacology; Calcium Channel Blockers/pharmacology; Diltiazem/pharmacology; Morphine/pharmacology; Respiration/drug effects; 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer/pharmacology; Analgesics, Non-Narcotic/pharmacology; Animals; Benzimidazoles/pharmacology; Clonidine/pharmacology; Dose-Response Relationship, Drug; Drug Synergism; Female; Fentanyl/pharmacology; Heroin/pharmacology; Macaca mulatta; Male; Nalbuphine/pharmacology; Pain Measurement/methods; Receptors, Opioid/agonists; Time Factors

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Collection: 01-internacional Database: MEDLINE Main subject: Respiration / Calcium Channel Blockers / Diltiazem / Analgesics, Opioid / Morphine Limits: Animals Language: En Journal: Eur J Pharmacol Year: 2000 Type: Article Affiliation country: United States

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