Involvement of mGluR(5) on acute nociceptive transmission.

Bordi, F; Ugolini, A

Bordi, F; Ugolini, A.

Affiliation

Bordi F; Pharmacology Department, GlaxoWellcome Medicine Research Centre, Via Fleming 4, 37100, Verona, Italy. fb23261@glaxowellcome.co.uk

Brain Res ; 871(2): 223-33, 2000 Jul 21.

Article in En | MEDLINE | ID: mdl-10899289

Subject(s)

Excitatory Amino Acid Antagonists/pharmacology; Nociceptors/drug effects; Receptors, Metabotropic Glutamate/drug effects; Receptors, Metabotropic Glutamate/metabolism; Synaptic Transmission/drug effects; Animals; Electric Stimulation; In Vitro Techniques; Indans/pharmacology; Injections, Intravenous; Male; Neurons/cytology; Neurons/drug effects; Neurons/metabolism; Nociceptors/metabolism; Pain/drug therapy; Pain/physiopathology; Pyridines/pharmacology; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate/antagonists & inhibitors; Receptors, N-Methyl-D-Aspartate/antagonists & inhibitors; Receptors, N-Methyl-D-Aspartate/drug effects; Receptors, N-Methyl-D-Aspartate/metabolism; Spinal Cord/cytology; Spinal Cord/drug effects; Spinal Cord/metabolism; Synaptic Transmission/physiology; Ventral Thalamic Nuclei/cytology; Ventral Thalamic Nuclei/drug effects; Ventral Thalamic Nuclei/physiopathology

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Collection: 01-internacional Database: MEDLINE Main subject: Nociceptors / Receptors, Metabotropic Glutamate / Synaptic Transmission / Excitatory Amino Acid Antagonists Type of study: Prognostic_studies Limits: Animals Language: En Journal: Brain Res Year: 2000 Type: Article Affiliation country: Italy

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