Role of the proteasome in Alzheimer's disease.

Checler, F; da Costa, C A; Ancolio, K; Chevallier, N; Lopez-Perez, E; Marambaud, P

Checler, F; da Costa, C A; Ancolio, K; Chevallier, N; Lopez-Perez, E; Marambaud, P.

Affiliation

Checler F; Institut de Pharmacologie Moléculaire et Cellulaire, UPR411 du CNRS, Sophia Antipolis, Valbonne, France. checler@ipmc.cnrs.fr

Biochim Biophys Acta ; 1502(1): 133-8, 2000 Jul 26.

Article in En | MEDLINE | ID: mdl-10899438

Subject(s)

Alzheimer Disease/pathology; Cysteine Endopeptidases/metabolism; Multienzyme Complexes/metabolism; Alzheimer Disease/enzymology; Alzheimer Disease/genetics; Amyloid Precursor Protein Secretases; Amyloid beta-Protein Precursor/metabolism; Aspartic Acid Endopeptidases; Cells, Cultured; Cysteine Endopeptidases/genetics; Drug Design; Endopeptidases/metabolism; Enzyme Activation/drug effects; Gene Targeting; Humans; Membrane Proteins/genetics; Membrane Proteins/metabolism; Multienzyme Complexes/antagonists & inhibitors; Multienzyme Complexes/genetics; Mutation; Plaque, Amyloid/metabolism; Presenilin-1; Presenilin-2; Proteasome Endopeptidase Complex; Ubiquitins/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Cysteine Endopeptidases / Alzheimer Disease / Multienzyme Complexes Limits: Humans Language: En Journal: Biochim Biophys Acta Year: 2000 Type: Article Affiliation country: France

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