Dose and time dependencies of 5-fluorouracil pharmacokinetics.

Terret, C; Erdociain, E; Guimbaud, R; Boisdron-Celle, M; McLeod, H L; Féty-Deporte, R; Lafont, T; Gamelin, E; Bugat, R; Canal, P; Chatelut, E

Terret, C; Erdociain, E; Guimbaud, R; Boisdron-Celle, M; McLeod, H L; Féty-Deporte, R; Lafont, T; Gamelin, E; Bugat, R; Canal, P; Chatelut, E.

Affiliation

Terret C; Institut Claudius-Regaud and Université Paul-Sabatier, Toulouse, France.

Clin Pharmacol Ther ; 68(3): 270-9, 2000 Sep.

Article in En | MEDLINE | ID: mdl-11014408

Subject(s)

Antimetabolites, Antineoplastic/pharmacokinetics; Colorectal Neoplasms/metabolism; Fluorouracil/pharmacokinetics; Adult; Aged; Antimetabolites, Antineoplastic/administration & dosage; Antimetabolites, Antineoplastic/blood; Colorectal Neoplasms/pathology; Drug Administration Schedule; Drug Interactions; Female; Fluorouracil/administration & dosage; Fluorouracil/blood; Humans; Infusions, Intravenous; Leucovorin/administration & dosage; Leucovorin/pharmacology; Liver Neoplasms/secondary; Male; Middle Aged; Models, Theoretical; Time Factors

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Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / Fluorouracil / Antimetabolites, Antineoplastic Type of study: Prognostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Clin Pharmacol Ther Year: 2000 Type: Article Affiliation country: France

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