Suppression of tumor cell growth both in nude mice and in culture by n-3 polyunsaturated fatty acids: mediation through cyclooxygenase-independent pathways.

Boudreau, M D; Sohn, K H; Rhee, S H; Lee, S W; Hunt, J D; Hwang, D H

Suppression of tumor cell growth both in nude mice and in culture by n-3 polyunsaturated fatty acids: mediation through cyclooxygenase-independent pathways.

Boudreau, M D; Sohn, K H; Rhee, S H; Lee, S W; Hunt, J D; Hwang, D H.

Affiliation

Boudreau MD; Pennington, Biomedical Research Center, Louisiana State University, Baton Rouge 70808, USA.

Cancer Res ; 61(4): 1386-91, 2001 Feb 15.

Article in En | MEDLINE | ID: mdl-11245439

Subject(s)

Colonic Neoplasms/pathology; Fatty Acids, Unsaturated/pharmacology; Isoenzymes/biosynthesis; Prostaglandin-Endoperoxide Synthases/biosynthesis; Triglycerides/pharmacology; Animals; Cell Adhesion/physiology; Cell Division/drug effects; Colonic Neoplasms/drug therapy; Colonic Neoplasms/enzymology; Cyclooxygenase 1; Cyclooxygenase 2; DNA, Complementary/genetics; Diet; Fatty Acids, Omega-3; Female; Growth Inhibitors/pharmacology; Humans; Isoenzymes/antagonists & inhibitors; Isoenzymes/genetics; Linoleic Acid/pharmacology; Membrane Proteins; Mice; Mice, Nude; Prostaglandin-Endoperoxide Synthases/genetics; Safflower Oil/pharmacology; Transfection

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Collection: 01-internacional Database: MEDLINE Main subject: Triglycerides / Prostaglandin-Endoperoxide Synthases / Colonic Neoplasms / Fatty Acids, Unsaturated / Isoenzymes Limits: Animals / Female / Humans Language: En Journal: Cancer Res Year: 2001 Type: Article Affiliation country: United States

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