Adenovirus-mediated wild-type p53 gene transfer in patients receiving chemotherapy for advanced non-small-cell lung cancer: results of a multicenter phase II study.

Schuler, M; Herrmann, R; De Greve, J L; Stewart, A K; Gatzemeier, U; Stewart, D J; Laufman, L; Gralla, R; Kuball, J; Buhl, R; Heussel, C P; Kommoss, F; Perruchoud, A P; Shepherd, F A; Fritz, M A; Horowitz, J A; Huber, C; Rochlitz, C

Schuler, M; Herrmann, R; De Greve, J L; Stewart, A K; Gatzemeier, U; Stewart, D J; Laufman, L; Gralla, R; Kuball, J; Buhl, R; Heussel, C P; Kommoss, F; Perruchoud, A P; Shepherd, F A; Fritz, M A; Horowitz, J A; Huber, C; Rochlitz, C.

Affiliation

Schuler M; Department of Medicine III, Johannes Gutenberg University, Mainz, Germany.

J Clin Oncol ; 19(6): 1750-8, 2001 Mar 15.

Article in En | MEDLINE | ID: mdl-11251006

Subject(s)

Antineoplastic Combined Chemotherapy Protocols/therapeutic use; Carcinoma, Non-Small-Cell Lung/drug therapy; Carcinoma, Non-Small-Cell Lung/genetics; Genes, p53/genetics; Genetic Therapy; Lung Neoplasms/drug therapy; Lung Neoplasms/genetics; Adenoviridae/genetics; Adult; Aged; Carboplatin/administration & dosage; Carcinoma, Non-Small-Cell Lung/pathology; Cisplatin/administration & dosage; Disease Progression; Female; Genetic Vectors; Humans; Lung Neoplasms/pathology; Male; Middle Aged; Paclitaxel/administration & dosage; Survival Analysis; Treatment Outcome

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Collection: 01-internacional Database: MEDLINE Main subject: Genetic Therapy / Antineoplastic Combined Chemotherapy Protocols / Genes, p53 / Carcinoma, Non-Small-Cell Lung / Lung Neoplasms Type of study: Clinical_trials / Prognostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: J Clin Oncol Year: 2001 Type: Article Affiliation country: Germany

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