Antiplatelet and antithrombotic activity of SL65.0472, a mixed 5-HT1B/5-HT2A receptor antagonist.

Berry, C N; Lorrain, J; Lochot, S; Delahaye, M; Lalé, A; Savi, P; Lechaire, I; Ferrari, P; Bernat, A; Schaeffer, P; Janiak, P; Duval, N; Grosset, A; Herbert, J M; O'Connor, S E

Berry, C N; Lorrain, J; Lochot, S; Delahaye, M; Lalé, A; Savi, P; Lechaire, I; Ferrari, P; Bernat, A; Schaeffer, P; Janiak, P; Duval, N; Grosset, A; Herbert, J M; O'Connor, S E.

Affiliation

Berry CN; Cardiovascular/Thrombosis Department, Sanofi-Synthélabo, Chilly Mazarin, France. christopher.berry@sanofi-synthelabo.com

Thromb Haemost ; 85(3): 521-8, 2001 Mar.

Article in En | MEDLINE | ID: mdl-11307825

Subject(s)

Piperazines/pharmacology; Platelet Activation/drug effects; Quinolines/pharmacology; Receptors, Serotonin/drug effects; Serotonin Antagonists/pharmacology; Thrombosis/drug therapy; Animals; Arteriovenous Shunt, Surgical; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Female; Fibrinolytic Agents/administration & dosage; Fibrinolytic Agents/pharmacology; Humans; Male; Piperazines/administration & dosage; Platelet Aggregation Inhibitors/administration & dosage; Platelet Aggregation Inhibitors/pharmacology; Quinolines/administration & dosage; Rabbits; Rats; Rats, Inbred Strains; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT2A; Serotonin Antagonists/administration & dosage; Thrombosis/prevention & control

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Collection: 01-internacional Database: MEDLINE Main subject: Piperazines / Quinolines / Serotonin Antagonists / Thrombosis / Platelet Activation / Receptors, Serotonin Limits: Animals / Female / Humans / Male Language: En Journal: Thromb Haemost Year: 2001 Type: Article Affiliation country: France

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