Inflammatory genes are upregulated in expanded ataxin-3-expressing cell lines and spinocerebellar ataxia type 3 brains.

Evert, B O; Vogt, I R; Kindermann, C; Ozimek, L; de Vos, R A; Brunt, E R; Schmitt, I; Klockgether, T; Wüllner, U

Evert, B O; Vogt, I R; Kindermann, C; Ozimek, L; de Vos, R A; Brunt, E R; Schmitt, I; Klockgether, T; Wüllner, U.

Affiliation

Evert BO; Department of Neurology, University of Bonn, 53105 Bonn, Germany. b.evert@uni-bonn.de

J Neurosci ; 21(15): 5389-96, 2001 Aug 01.

Article in En | MEDLINE | ID: mdl-11466410

Subject(s)

Brain/metabolism; Inflammation/metabolism; Machado-Joseph Disease/metabolism; Membrane Proteins; Nerve Tissue Proteins/biosynthesis; Up-Regulation; Amyloid beta-Protein Precursor/genetics; Amyloid beta-Protein Precursor/metabolism; Animals; Ataxin-3; Brain/pathology; Cells, Cultured; Chemokine CXCL12; Chemokines, CXC/genetics; Chemokines, CXC/metabolism; Gene Expression Profiling; Humans; Immunohistochemistry; Inflammation/genetics; Interleukin-1 Receptor-Like 1 Protein; Interleukin-18 Receptor alpha Subunit; Machado-Joseph Disease/pathology; Matrix Metalloproteinase 2/genetics; Matrix Metalloproteinase 2/metabolism; Nerve Tissue Proteins/genetics; Neurons/metabolism; Neurons/pathology; Nuclear Proteins; Pons/metabolism; Pons/pathology; Proteins/genetics; Proteins/metabolism; RNA, Messenger/metabolism; Rats; Receptors, Cell Surface; Receptors, Interleukin; Receptors, Interleukin-18; Repressor Proteins; Transcription Factors; Trinucleotide Repeat Expansion/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain / Up-Regulation / Machado-Joseph Disease / Inflammation / Membrane Proteins / Nerve Tissue Proteins Type of study: Prognostic_studies Language: En Journal: J Neurosci Year: 2001 Type: Article Affiliation country: Germany

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