Megestrol acetate for estrus postponement in the bitch.
J Am Vet Med Assoc
; 167(4): 285-7, 1975 Aug 15.
Article
in En
| MEDLINE
| ID: mdl-1150522
ABSTRACT
PIP: The postponement of estrus by megestrol acetate (MA) was evaluated in 389 female dogs. MA was administered for 8 days in a daily dose of 2.2 mg/kg body weight, beginning in early proestrus. Estrus was suppressed in 357 of these animals (92%). An additional 119 bitches in anestrus received MA in a daily dose of .55 mg/kg body weight for 32 days. Estrus was suppressed in 115 of these animals (97%). Pyometra was observed in 3 of 389 animals (.8%); other adverse affects were minimal. 19 animals received MA in a daily dose of .55 mg/kg body weight for 32 days, regardless of the stage of the estrous cycle. 15 of these bitches whelped normal litters after the 1st posttreatment estrus, and 4 after mating at the 2nd posttreatment estrus. Litter characteristics were similar to those observed in controls.
Key words
Animals, Laboratory; Clinical Research; Comparative Studies; Contraception; Contraceptive Agents, Female--administraction and dosage; Contraceptive Agents, Female--side effects; Contraceptive Agents, Progestin--administraction and dosage; Contraceptive Agents, Progestin--side effects; Contraceptive Agents--administraction and dosage; Contraceptive Agents--side effects; Contraceptive Mode Of Action; Family Planning; Megestrol Acetate--administraction and dosage; Megestrol Acetate--side effects; Oral Contraceptives; Ovulation Suppression; Research Methodology; Reversibility; Studies
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Estrus
/
Dogs
/
Megestrol
Limits:
Animals
/
Pregnancy
Language:
En
Journal:
J Am Vet Med Assoc
Year:
1975
Type:
Article