Catechol-O-methyltransferase (COMT)-mediated metabolism of catechol estrogens: comparison of wild-type and variant COMT isoforms.

Dawling, S; Roodi, N; Mernaugh, R L; Wang, X; Parl, F F

Dawling, S; Roodi, N; Mernaugh, R L; Wang, X; Parl, F F.

Affiliation

Dawling S; Department of Pathology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA.

Cancer Res ; 61(18): 6716-22, 2001 Sep 15.

Article in En | MEDLINE | ID: mdl-11559542

Subject(s)

Catechol O-Methyltransferase/metabolism; Estrogens, Catechol/metabolism; Alleles; Breast Neoplasms/enzymology; Breast Neoplasms/genetics; Catechol O-Methyltransferase/genetics; Cloning, Molecular; Enzyme Activation; Enzyme Stability; Enzyme-Linked Immunosorbent Assay; Gas Chromatography-Mass Spectrometry; Humans; Isoenzymes/genetics; Isoenzymes/metabolism; Methylation; Polymerase Chain Reaction; Recombinant Proteins/genetics; Recombinant Proteins/metabolism; Tumor Cells, Cultured

Search on Google

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Catechol O-Methyltransferase / Estrogens, Catechol Limits: Humans Language: En Journal: Cancer Res Year: 2001 Type: Article Affiliation country: United States

Search on Google

XML

PubMed Links