Evidence that a burst of DNA depurination in SENCAR mouse skin induces error-prone repair and forms mutations in the H-ras gene.

Chakravarti, D; Mailander, P C; Li, K M; Higginbotham, S; Zhang, H L; Gross, M L; Meza, J L; Cavalieri, E L; Rogan, E G

Chakravarti, D; Mailander, P C; Li, K M; Higginbotham, S; Zhang, H L; Gross, M L; Meza, J L; Cavalieri, E L; Rogan, E G.

Affiliation

Chakravarti D; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, 986805 Nebraska Medical Center, Omaha, Nebraska 68198-6805, USA. dchakrav@unmc.edu

Oncogene ; 20(55): 7945-53, 2001 Nov 29.

Article in En | MEDLINE | ID: mdl-11753677

Subject(s)

DNA Adducts/genetics; DNA Damage/genetics; DNA Repair/genetics; Estradiol/analogs & derivatives; Genes, ras/genetics; Mutagenesis/genetics; Skin/metabolism; Animals; Artifacts; Base Sequence; DNA Adducts/chemistry; DNA Adducts/drug effects; DNA Damage/drug effects; DNA Mutational Analysis; DNA Repair/drug effects; Estradiol/chemistry; Estradiol/pharmacology; Female; Mice; Mice, Inbred SENCAR; Mutagens/chemistry; Mutagens/pharmacology; Nucleic Acid Heteroduplexes/drug effects; Nucleic Acid Heteroduplexes/genetics; Point Mutation/genetics; Polymerase Chain Reaction; Skin/drug effects

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Collection: 01-internacional Database: MEDLINE Main subject: Skin / DNA Damage / Mutagenesis / Genes, ras / DNA Adducts / DNA Repair / Estradiol Limits: Animals Language: En Journal: Oncogene Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2001 Type: Article Affiliation country: United States

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